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CXCL10 CXCL10 GNAQ GNAQ ADRA1A ADRA1A ADM2 ADM2 MC3R MC3R GNAL GNAL DRD3 DRD3 RXFP1 RXFP1 RAMP2 RAMP2 CHGA CHGA CXCL11 CXCL11 ADORA2B ADORA2B GPHB5 GPHB5 GPR119 GPR119 S1PR1 S1PR1 ADCY5 ADCY5 S1PR4 S1PR4 RXFP2 RXFP2 ADCY2 ADCY2 DRD2 DRD2 UCN2 UCN2 LOC102269605 LOC102269605 LOC102285011 LOC102285011 LHCGR LHCGR MC1R MC1R ADGRB1 ADGRB1 GHRHR GHRHR LPAR3 LPAR3 GPR65 GPR65 ADGRG7 ADGRG7 MC5R MC5R MC2R MC2R PTHLH PTHLH PTH PTH ADGRL4 ADGRL4 PTGFR PTGFR M91_20249 M91_20249 CHRM3 CHRM3 ADCY4 ADCY4 SLC9A3R1 SLC9A3R1 TMEM116 TMEM116 GPHA2 GPHA2 DRD1 DRD1 UCN3 UCN3 ADGRF3 ADGRF3 GPR101 GPR101 ADCY3 ADCY3 PTRHD1 PTRHD1 RAMP3 RAMP3 ADCY1 ADCY1 ENSBMUP00000008211 ENSBMUP00000008211 ADRB3 ADRB3 ADCY8 ADCY8 PTGIR PTGIR GNG2 GNG2 GPR161 GPR161 ADGRF1 ADGRF1 S1PR5 S1PR5 GPR26 GPR26 GPR4 GPR4 PTGER2 PTGER2 M91_16327 M91_16327 CALCR CALCR PTGER3 PTGER3 ADRA1B ADRA1B ADCY9 ADCY9 DRD5 DRD5 ADGRF5 ADGRF5 LOC102268959 LOC102268959 PPBP PPBP ADGRB3 ADGRB3 GPR157 GPR157 RAPGEF4 RAPGEF4 ADGRG3 ADGRG3 ADGRG1 ADGRG1 ADGRG5 ADGRG5 ABCA2 ABCA2 GHRH GHRH GIP GIP ADGRD1 ADGRD1 GCGR GCGR S1PR3 S1PR3 GPR6 GPR6 PTH1R PTH1R GCG GCG ADGRE3 ADGRE3 ABCA1 ABCA1 ADRB2 ADRB2 TBXA2R TBXA2R ADGRE5 ADGRE5 LOC102266153 LOC102266153 LPAR2 LPAR2 ADM5 ADM5 GIPR GIPR S1PR2 S1PR2 TSHR TSHR ADRA1D ADRA1D ADCYAP1 ADCYAP1 M91_02589 M91_02589 HTR5A HTR5A ADORA2A ADORA2A ADGRG2 ADGRG2 ADCY6 ADCY6 CALCRL CALCRL GPR12 GPR12 LPAR1 LPAR1 VIP VIP GNB1 GNB1 GLP1R GLP1R ADGRF4 ADGRF4 ADGRF2 ADGRF2 RAPGEF2 RAPGEF2 ADRA2B ADRA2B CRHR1 CRHR1 ADGRE1 ADGRE1 GNA13 GNA13 ENSBMUP00000034400 ENSBMUP00000034400 LOC102277268 LOC102277268 M91_08685 M91_08685 ADCY7 ADCY7 ADM ADM PTGER4 PTGER4 GPR3 GPR3 MC4R MC4R LOC102268826 LOC102268826 LOC102268273 LOC102268273 M91_20034 M91_20034 CXCL9 CXCL9 PLN PLN ADGRG6 ADGRG6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCL10C-X-C motif chemokine. (101 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
ADRA1AAlpha-1A adrenergic receptor. (455 aa)
ADM2ADM2 protein. (174 aa)
MC3RMelanocortin receptor 3. (323 aa)
GNALGuanine nucleotide-binding protein G(olf) subunit alpha. (135 aa)
DRD3D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (395 aa)
RXFP1Relaxin receptor 1. (762 aa)
RAMP2Receptor activity-modifying protein 2. (207 aa)
CHGAChromogranin-A. (449 aa)
CXCL11C-X-C motif chemokine. (95 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (324 aa)
GPHB5Glycoprotein hormone beta-5. (130 aa)
GPR119Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (335 aa)
S1PR1Sphingosine 1-phosphate receptor 1. (382 aa)
ADCY5Adenylate cyclase type 5. (1073 aa)
S1PR4Sphingosine 1-phosphate receptor 4. (385 aa)
RXFP2Relaxin receptor 2. (753 aa)
ADCY2Adenylate cyclase type 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (873 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
UCN2Urocortin-2. (112 aa)
LOC102269605ATP-binding cassette sub-family A member 1-like. (159 aa)
LOC102285011Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (644 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
MC1RMelanocortin 1 receptor. (317 aa)
ADGRB1Brain-specific angiogenesis inhibitor 1; Belongs to the G-protein coupled receptor 2 family. (1577 aa)
GHRHRGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
GPR65Psychosine receptor; Belongs to the G-protein coupled receptor 1 family. (334 aa)
ADGRG7Putative G-protein coupled receptor 128; Belongs to the G-protein coupled receptor 2 family. (795 aa)
MC5RMelanocortin receptor 5. (325 aa)
MC2RAdrenocorticotropic hormone receptor. (297 aa)
PTHLHParathyroid hormone-related protein. (164 aa)
PTHParathyroid hormone. (111 aa)
ADGRL4EGF, latrophilin and seven transmembrane domain-containing protein 1; Belongs to the G-protein coupled receptor 2 family. (689 aa)
PTGFRProstaglandin F2-alpha receptor. (362 aa)
M91_20249EGF-like module-containing mucin-like hormone receptor-like 2; Belongs to the G-protein coupled receptor 2 family. (795 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (204 aa)
TMEM116Transmembrane protein 116. (344 aa)
GPHA2Glycoprotein hormone alpha-2. (129 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
UCN3Urocortin-3. (166 aa)
ADGRF3Putative G-protein coupled receptor 113; Belongs to the G-protein coupled receptor 2 family. (961 aa)
GPR101Putative G-protein coupled receptor 101; Belongs to the G-protein coupled receptor 1 family. (503 aa)
ADCY3Adenylate cyclase type 3. (1145 aa)
PTRHD1Uncharacterized protein. (147 aa)
RAMP3Receptor activity-modifying protein 3. (150 aa)
ADCY1Adenylate cyclase 1. (310 aa)
ENSBMUP00000008211annotation not available (284 aa)
ADRB3Beta-3 adrenergic receptor. (396 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1251 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (548 aa)
ADGRF1Putative G-protein coupled receptor 110; Belongs to the G-protein coupled receptor 2 family. (907 aa)
S1PR5Sphingosine 1-phosphate receptor 5. (403 aa)
GPR26G-protein coupled receptor 26. (335 aa)
GPR4G-protein coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (352 aa)
M91_16327EGF-like module-containing mucin-like hormone receptor-like 2; Belongs to the G-protein coupled receptor 2 family. (435 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (478 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype. (387 aa)
ADRA1BAlpha-1B adrenergic receptor. (521 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (473 aa)
ADGRF5Putative G-protein coupled receptor 116; Belongs to the G-protein coupled receptor 2 family. (983 aa)
LOC102268959C-X-C motif chemokine. (104 aa)
PPBPC-X-C motif chemokine. (119 aa)
ADGRB3Brain-specific angiogenesis inhibitor 3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
GPR157Putative G-protein coupled receptor 157. (327 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1007 aa)
ADGRG3Putative G-protein coupled receptor 97; Belongs to the G-protein coupled receptor 2 family. (550 aa)
ADGRG1G-protein coupled receptor 56; Belongs to the G-protein coupled receptor 2 family. (695 aa)
ADGRG5Adhesion G protein-coupled receptor G5. (517 aa)
ABCA2ATP binding cassette subfamily A member 2. (2264 aa)
GHRHSomatoliberin. (106 aa)
GIPGastric inhibitory polypeptide. (155 aa)
ADGRD1Putative G-protein coupled receptor 133; Belongs to the G-protein coupled receptor 2 family. (902 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
GPR6G-protein coupled receptor 6; Belongs to the G-protein coupled receptor 1 family. (365 aa)
PTH1RParathyroid hormone 1 receptor. (575 aa)
GCGGlucagon. (180 aa)
ADGRE3EGF-like module-containing mucin-like hormone receptor-like 3; Belongs to the G-protein coupled receptor 2 family. (645 aa)
ABCA1ATP-binding cassette sub-family A member 1. (2120 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
ADGRE5CD97 antigen; Belongs to the G-protein coupled receptor 2 family. (827 aa)
LOC102266153Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (394 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
ADM5Adrenomedullin 5 (putative). (113 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
S1PR2Sphingosine 1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (697 aa)
ADRA1DAlpha-1D adrenergic receptor. (528 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
M91_02589Calcitonin receptor-stimulating peptide 2. (167 aa)
HTR5A5-hydroxytryptamine receptor 5A. (359 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (504 aa)
ADGRG2Adhesion G protein-coupled receptor G2. (1018 aa)
ADCY6Adenylate cyclase 6. (1163 aa)
CALCRLCalcitonin related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
GPR12G-protein coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
VIPVIP peptide. (170 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GLP1RGlucagon like peptide 1 receptor. (456 aa)
ADGRF4Putative G-protein coupled receptor 115; Belongs to the G-protein coupled receptor 2 family. (694 aa)
ADGRF2Putative G-protein coupled receptor 111; Belongs to the G-protein coupled receptor 2 family. (643 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1676 aa)
ADRA2BAlpha-2B adrenergic receptor. (447 aa)
CRHR1Corticotropin releasing hormone receptor 1. (415 aa)
ADGRE1EGF-like module-containing mucin-like hormone receptor-like 1; Belongs to the G-protein coupled receptor 2 family. (1249 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
ENSBMUP00000034400annotation not available (112 aa)
LOC102277268EGF-like module-containing mucin-like hormone receptor-like 4; Belongs to the G-protein coupled receptor 2 family. (645 aa)
M91_08685Putative EGF-like module-containing mucin-like hormone receptor-like 4; Belongs to the G-protein coupled receptor 2 family. (545 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1097 aa)
ADMADM protein. (457 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (487 aa)
GPR3G-protein coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (322 aa)
MC4RMelanocortin receptor 4. (333 aa)
LOC102268826Calcitonin receptor-stimulating peptide 1. (125 aa)
LOC102268273Calcitonin. (120 aa)
M91_20034Calcitonin. (133 aa)
CXCL9C-X-C motif chemokine. (125 aa)
PLNPhospholamban. (52 aa)
ADGRG6G-protein coupled receptor 126; Belongs to the G-protein coupled receptor 2 family. (1258 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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