(9 nodes) Adenylate cyclase-activating dopamine receptor signaling pathway network (Bos mutus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DRD3	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (395 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	GNAL	Guanine nucleotide-binding protein G(olf) subunit alpha. (135 aa)
	LOC102266153	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (394 aa)
	DRD5	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (473 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
	DRD1	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (204 aa)
	ADCY5	Adenylate cyclase type 5. (1073 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GNAL	ENSBMUP00000017252	ENSBMUP00000021662	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(olf) subunit alpha.	0.776
ADCY5	GNB1	ENSBMUP00000017252	ENSBMUP00000031711	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.461
ADCY5	GNG2	ENSBMUP00000017252	ENSBMUP00000006501	Adenylate cyclase type 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.576
ADCY5	LOC102266153	ENSBMUP00000017252	ENSBMUP00000026048	Adenylate cyclase type 5.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas.	0.988
DRD1	DRD5	ENSBMUP00000009313	ENSBMUP00000003325	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.911
DRD1	GNAL	ENSBMUP00000009313	ENSBMUP00000021662	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(olf) subunit alpha.	0.970
DRD1	GNB1	ENSBMUP00000009313	ENSBMUP00000031711	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.587
DRD1	GNG2	ENSBMUP00000009313	ENSBMUP00000006501	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.426
DRD1	LOC102266153	ENSBMUP00000009313	ENSBMUP00000026048	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas.	0.970
DRD3	GNAL	ENSBMUP00000021286	ENSBMUP00000021662	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(olf) subunit alpha.	0.540
DRD3	GNB1	ENSBMUP00000021286	ENSBMUP00000031711	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.675
DRD3	GNG2	ENSBMUP00000021286	ENSBMUP00000006501	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.547
DRD3	LOC102266153	ENSBMUP00000021286	ENSBMUP00000026048	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas.	0.540
DRD5	DRD1	ENSBMUP00000003325	ENSBMUP00000009313	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.911
DRD5	GNAL	ENSBMUP00000003325	ENSBMUP00000021662	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(olf) subunit alpha.	0.970
DRD5	GNB1	ENSBMUP00000003325	ENSBMUP00000031711	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.587
DRD5	GNG2	ENSBMUP00000003325	ENSBMUP00000006501	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.426
DRD5	LOC102266153	ENSBMUP00000003325	ENSBMUP00000026048	D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas.	0.970
GNAL	ADCY5	ENSBMUP00000021662	ENSBMUP00000017252	Guanine nucleotide-binding protein G(olf) subunit alpha.	Adenylate cyclase type 5.	0.776
GNAL	DRD1	ENSBMUP00000021662	ENSBMUP00000009313	Guanine nucleotide-binding protein G(olf) subunit alpha.	D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.970