STRINGSTRING
CDH23 CDH23 OTOG OTOG TECTB TECTB USH1C USH1C TMTC4 TMTC4 FZD4 FZD4 GJB2 GJB2 GJB6 GJB6 CFAP57 CFAP57 CEACAM16 CEACAM16 WFS1 WFS1 CCDC50 CCDC50 STRC STRC KIT KIT CLRN1 CLRN1 SRRM4 SRRM4 CABP2 CABP2 P2RX2 P2RX2 COL1A1 COL1A1 SPTBN4 SPTBN4 USH2A USH2A FAM107B FAM107B CDC14A CDC14A MYO7B MYO7B MARVELD2 MARVELD2 MYO7A MYO7A KCNQ1 KCNQ1 AXIN1 AXIN1 OTOA OTOA MKKS MKKS GABRB2 GABRB2 CACNA1D CACNA1D ENSBMUP00000033803 ENSBMUP00000033803 SIX1 SIX1 DCDC2 DCDC2 ENSBMUP00000034348 ENSBMUP00000034348 ATP6V0A4 ATP6V0A4 DDIT3 DDIT3 RPL38 RPL38 MYO1A MYO1A TPRN TPRN COL11A1 COL11A1 GABRA5 GABRA5 CEMIP CEMIP PCDH15 PCDH15 EPYC EPYC LRP2 LRP2 TFAP2A TFAP2A PDZD7 PDZD7 MYO3B MYO3B BARHL1 BARHL1 TMIE TMIE LRIG2 LRIG2 MYO3A MYO3A LHFPL5 LHFPL5 COL2A1 COL2A1 GRM7 GRM7 ATP8B1 ATP8B1 CASP3 CASP3 ATP6V1B1 ATP6V1B1 PKHD1L1 PKHD1L1 KCNQ4 KCNQ4 USP53 USP53 NIPBL NIPBL SLC1A3 SLC1A3 CDKN2D CDKN2D ENSBMUP00000006145 ENSBMUP00000006145 ATP6V0A4-2 ATP6V0A4-2 POU4F2 POU4F2 FBXO11 FBXO11 HPN HPN EPS8L2 EPS8L2 MYH14 MYH14 NAV2 NAV2 TBL1X TBL1X HOMER2 HOMER2 CNTN5 CNTN5 KCNMA1 KCNMA1 ATP2B2 ATP2B2 TSPEAR TSPEAR HEXA HEXA SLC9A3R1 SLC9A3R1 POU4F3 POU4F3 USH1G USH1G EYA4 EYA4 GRXCR2 GRXCR2 COL11A2 COL11A2 ROR1 ROR1 LHFPL3 LHFPL3 CDKN1B CDKN1B LOXHD1 LOXHD1 M91_03329 M91_03329 M91_03330 M91_03330 CLRN2 CLRN2 OTOS OTOS TECTA TECTA C2orf66 C2orf66 PGAP1 PGAP1 ASIC2 ASIC2 SOBP SOBP SPNS2 SPNS2 PJVK PJVK SLC26A5 SLC26A5 CLIC5 CLIC5 LRIG1 LRIG1 TMC1 TMC1 CLRN3 CLRN3 SNAI2 SNAI2 ADGRV1 ADGRV1 LHFPL4 LHFPL4 ENSBMUP00000016022 ENSBMUP00000016022 CHD7 CHD7 ENSBMUP00000016101 ENSBMUP00000016101 TMPRSS3 TMPRSS3 THRB THRB COCH COCH RIPOR2 RIPOR2 GPX1 GPX1 SCARB2 SCARB2 MYO6 MYO6 TUB TUB LOC102271469 LOC102271469 WHRN WHRN SLC52A3 SLC52A3 OTOGL OTOGL CHRNA9 CHRNA9 SPRY2 SPRY2 MYO15A MYO15A LOC102277953 LOC102277953
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDH23Cadherin-23. (3305 aa)
OTOGOtogelin. (2920 aa)
TECTBBeta-tectorin. (342 aa)
USH1CUSH1 protein network component harmonin. (551 aa)
TMTC4Transmembrane and TPR repeat-containing protein 4. (667 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
CFAP57WD repeat-containing protein 65. (1137 aa)
CEACAM16Carcinoembryonic antigen-related cell adhesion molecule 16. (424 aa)
WFS1Wolframin. (871 aa)
CCDC50Coiled-coil domain-containing protein 50. (481 aa)
STRCStereocilin. (1763 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
CLRN1Clarin-1. (232 aa)
SRRM4Serine/arginine repetitive matrix protein 4. (356 aa)
CABP2Calcium-binding protein 2. (222 aa)
P2RX2Purinergic receptor P2X 2. (406 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2477 aa)
USH2AUsherin. (5202 aa)
FAM107BProtein FAM107B. (307 aa)
CDC14ADual specificity protein phosphatase CDC14A. (625 aa)
MYO7BMyosin-VIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2114 aa)
MARVELD2MARVEL domain-containing protein 2. (559 aa)
MYO7AMyosin-VIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2177 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (676 aa)
AXIN1Axin-1. (865 aa)
OTOAOtoancorin. (1115 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
ENSBMUP00000033803annotation not available (230 aa)
SIX1Homeobox protein SIX1. (284 aa)
DCDC2Doublecortin domain-containing protein 2. (435 aa)
ENSBMUP00000034348annotation not available (70 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (792 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
RPL3860S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
MYO1AMyosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
TPRNTaperin. (466 aa)
COL11A1Collagen alpha-1(XI) chain. (1799 aa)
GABRA5Gamma-aminobutyric acid receptor subunit alpha-5. (312 aa)
CEMIPProtein KIAA1199. (1358 aa)
PCDH15Protocadherin-15-like. (1147 aa)
EPYCEpiphycan. (321 aa)
LRP2Low density lipoprotein-related protein 2. (4641 aa)
TFAP2ATranscription factor AP-2 alpha/beta. (189 aa)
PDZD7PDZ domain-containing protein 7. (1022 aa)
MYO3BMyosin IIIB. (1340 aa)
BARHL1BarH-like 1 homeobox protein. (328 aa)
TMIETransmembrane inner ear expressed protein. (155 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (962 aa)
MYO3AMyosin-IIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (248 aa)
LHFPL5Tetraspan membrane protein of hair cell stereocilia. (205 aa)
COL2A1Collagen alpha-1(II) chain. (1486 aa)
GRM7Metabotropic glutamate receptor 7. (915 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
CASP3Caspase 3. (276 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
PKHD1L1Fibrocystin-L. (4245 aa)
KCNQ4Potassium voltage-gated channel subfamily KQT member 4; Belongs to the potassium channel family. (695 aa)
USP53Ubiquitin specific peptidase 53. (1112 aa)
NIPBLCohesin loading factor subunit SCC2. (2804 aa)
SLC1A3Amino acid transporter. (542 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (151 aa)
ENSBMUP00000006145annotation not available (102 aa)
ATP6V0A4-2V-type H+-transporting ATPase subunit a. (135 aa)
POU4F2POU domain protein. (408 aa)
FBXO11F-box only protein 11. (928 aa)
HPNSerine protease hepsin; Belongs to the peptidase S1 family. (417 aa)
EPS8L2EPS8 like 2. (561 aa)
MYH14Myosin-14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2039 aa)
NAV2Neuron navigator 2. (2430 aa)
TBL1XF-box-like/WD repeat-containing protein TBL1X. (526 aa)
HOMER2Homer protein-like protein 2. (344 aa)
CNTN5Contactin-5. (1032 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1. (1282 aa)
ATP2B2Plasma membrane calcium-transporting ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1246 aa)
TSPEARProtein TSPEAR. (608 aa)
HEXABeta-hexosaminidase. (529 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (204 aa)
POU4F3POU domain protein. (338 aa)
USH1GUsher syndrome type-1G protein-like protein. (462 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (639 aa)
GRXCR2Glutaredoxin domain-containing cysteine-rich protein 2. (246 aa)
COL11A2Collagen type XI alpha 2 chain. (1736 aa)
ROR1Tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (874 aa)
LHFPL3LHFPL tetraspan subfamily member protein. (222 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
LOXHD1Lipoxygenase-like protein domain-containing protein 1. (1115 aa)
M91_03329Putative myosin-XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1430 aa)
M91_03330Uncharacterized protein. (414 aa)
CLRN2Clarin-2. (232 aa)
OTOSOtospiralin. (89 aa)
TECTAAlpha-tectorin. (2155 aa)
C2orf66Uncharacterized protein. (141 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
ASIC2Amiloride-sensitive cation channel 1, neuronal; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (341 aa)
SOBPSine oculis-binding protein-like protein. (873 aa)
SPNS2Protein spinster-like protein 2. (549 aa)
PJVKPejvakin. (352 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (231 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1064 aa)
TMC1Transmembrane channel-like protein. (759 aa)
CLRN3Clarin 3. (226 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
ADGRV1Adhesion G protein-coupled receptor V1. (6294 aa)
LHFPL4Lipoma HMGIC fusion partner-like 4 protein. (251 aa)
ENSBMUP00000016022annotation not available (1142 aa)
CHD7Chromodomain helicase DNA binding protein 7. (104 aa)
ENSBMUP00000016101annotation not available (925 aa)
TMPRSS3Transmembrane protease serine 3; Belongs to the peptidase S1 family. (454 aa)
THRBThyroid hormone receptor beta. (476 aa)
COCHCochlin. (550 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1045 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (155 aa)
SCARB2Lysosome membrane protein 2; Belongs to the CD36 family. (478 aa)
MYO6Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (790 aa)
TUBTubby bipartite transcription factor. (561 aa)
LOC102271469GRB2-related adapter protein. (219 aa)
WHRNWhirlin. (907 aa)
SLC52A3Riboflavin transporter 2. (467 aa)
OTOGLUncharacterized protein. (1494 aa)
CHRNA9Neuronal acetylcholine receptor subunit alpha-9. (479 aa)
SPRY2Protein sprouty-like protein 2. (315 aa)
MYO15AMyosin XVA. (792 aa)
LOC102277953Transmembrane O-methyltransferase. (258 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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