(26 nodes) Regulation of fibroblast migration network (Bos mutus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	ENSBMUP00000006201	annotation not available (95 aa)
	AQP1	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	PRR5L	Proline rich 5 like. (368 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (204 aa)
	APPL2	DCC-interacting protein 13-beta. (664 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
	ITGB1BP1	Integrin beta-1-binding protein 1. (200 aa)
	RCC2	Protein RCC2. (522 aa)
	CLN3	Battenin. (438 aa)
	THBS1	Thrombospondin-1. (1204 aa)
	DMTN	Dematin. (405 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	BRAF	Serine/threonine-protein kinase B-raf. (790 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (814 aa)
	GNA12	Guanine nucleotide-binding protein subunit alpha-12. (291 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (513 aa)
	HYAL2	Hyaluronidase. (473 aa)
	WDPCP	WD repeat-containing and planar cell polarity effector protein. (100 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ITGB3	Integrin beta. (788 aa)
	GNA13	Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
	ENSBMUP00000034400	annotation not available (112 aa)
	AKT1	RAC serine/threonine-protein kinase. (421 aa)
	APPL1	DCC-interacting protein 13-alpha. (708 aa)
	DDR2	Discoidin domain-containing receptor 2. (855 aa)
	BAG4	BAG family molecular chaperone regulator 4. (416 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	APPL1	ENSBMUP00000035432	ENSBMUP00000017333	RAC serine/threonine-protein kinase.	DCC-interacting protein 13-alpha.	0.807
AKT1	APPL2	ENSBMUP00000035432	ENSBMUP00000009727	RAC serine/threonine-protein kinase.	DCC-interacting protein 13-beta.	0.799
AKT1	FGF2	ENSBMUP00000035432	ENSBMUP00000018775	RAC serine/threonine-protein kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.474
AKT1	TGFB1	ENSBMUP00000035432	ENSBMUP00000031280	RAC serine/threonine-protein kinase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.608
APPL1	AKT1	ENSBMUP00000017333	ENSBMUP00000035432	DCC-interacting protein 13-alpha.	RAC serine/threonine-protein kinase.	0.807
APPL1	APPL2	ENSBMUP00000017333	ENSBMUP00000009727	DCC-interacting protein 13-alpha.	DCC-interacting protein 13-beta.	0.999
APPL2	AKT1	ENSBMUP00000009727	ENSBMUP00000035432	DCC-interacting protein 13-beta.	RAC serine/threonine-protein kinase.	0.799
APPL2	APPL1	ENSBMUP00000009727	ENSBMUP00000017333	DCC-interacting protein 13-beta.	DCC-interacting protein 13-alpha.	0.999
BRAF	ITGB3	ENSBMUP00000019105	ENSBMUP00000033383	Serine/threonine-protein kinase B-raf.	Integrin beta.	0.546
CORO1C	RCC2	ENSBMUP00000028097	ENSBMUP00000004308	Coronin; Belongs to the WD repeat coronin family.	Protein RCC2.	0.601
ENSBMUP00000034400	GNA12	ENSBMUP00000034400	ENSBMUP00000026371	annotation not available	Guanine nucleotide-binding protein subunit alpha-12.	0.848
FGF2	AKT1	ENSBMUP00000018775	ENSBMUP00000035432	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	RAC serine/threonine-protein kinase.	0.474
FGF2	HYAL2	ENSBMUP00000018775	ENSBMUP00000029097	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hyaluronidase.	0.470
FGF2	ITGB1	ENSBMUP00000018775	ENSBMUP00000020772	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Integrin beta; Belongs to the integrin beta chain family.	0.576
FGF2	TGFB1	ENSBMUP00000018775	ENSBMUP00000031280	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.775
FGF2	THBS1	ENSBMUP00000018775	ENSBMUP00000000400	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Thrombospondin-1.	0.656
GNA12	ENSBMUP00000034400	ENSBMUP00000026371	ENSBMUP00000034400	Guanine nucleotide-binding protein subunit alpha-12.	annotation not available	0.848
GNA12	GNA13	ENSBMUP00000026371	ENSBMUP00000034389	Guanine nucleotide-binding protein subunit alpha-12.	Guanine nucleotide-binding protein subunit alpha-13.	0.981
GNA13	GNA12	ENSBMUP00000034389	ENSBMUP00000026371	Guanine nucleotide-binding protein subunit alpha-13.	Guanine nucleotide-binding protein subunit alpha-12.	0.981
GNA13	ITGB3	ENSBMUP00000034389	ENSBMUP00000033383	Guanine nucleotide-binding protein subunit alpha-13.	Integrin beta.	0.929