STRINGSTRING
APC APC KCNAB2 KCNAB2 GNGT2 GNGT2 SRC SRC GNAT3 GNAT3 GNAI1 GNAI1 FCN1 FCN1 ERRFI1 ERRFI1 GNB2 GNB2 ENSBMUP00000002129 ENSBMUP00000002129 SNX9 SNX9 STAC2 STAC2 GNAZ GNAZ CDH1 CDH1 CDH3 CDH3 BLK BLK CDH17 CDH17 LOC102269855 LOC102269855 SYTL3 SYTL3 PLG PLG GNAT2 GNAT2 GNAI3 GNAI3 APC2 APC2 GNGT1 GNGT1 GNG11 GNG11 CTNNA2 CTNNA2 SCUBE1 SCUBE1 MFGE8 MFGE8 KCNIP1 KCNIP1 DLG4 DLG4 FRK FRK SNX5 SNX5 ALOX15 ALOX15 CDH16 CDH16 CDH19 CDH19 ENSBMUP00000006446 ENSBMUP00000006446 GNG2 GNG2 GNG8 GNG8 TF TF CDH5 CDH5 FER FER CDH10 CDH10 CDH22 CDH22 GRAMD1A GRAMD1A CDH11 CDH11 TNK1 TNK1 KCNAB1 KCNAB1 ESYT3 ESYT3 M91_02967 M91_02967 M91_13582 M91_13582 IQGAP1 IQGAP1 GRAMD2A GRAMD2A FES FES HIP1 HIP1 MYZAP MYZAP CDH4 CDH4 ENSBMUP00000011477 ENSBMUP00000011477 KPNA2 KPNA2 LCK LCK RS1 RS1 GNG4 GNG4 CDH20 CDH20 GNB3 GNB3 NUMB NUMB SYK SYK GNB5 GNB5 CDH8 CDH8 GNG12 GNG12 LOC102270606 LOC102270606 SNAP91 SNAP91 USP50 USP50 ANXA1 ANXA1 ENSBMUP00000014874 ENSBMUP00000014874 LYN LYN SERPINE2 SERPINE2 LOC102271265 LOC102271265 CDH6 CDH6 DCHS1 DCHS1 CDH15 CDH15 PTK2 PTK2 GNA15 GNA15 GNA11 GNA11 GNG7 GNG7 CDH18 CDH18 CAV2 CAV2 CTNNA1 CTNNA1 CYTH3 CYTH3 WNT2 WNT2 RHOA RHOA NPTX2 NPTX2 HCK HCK CBY3 CBY3 CDH9 CDH9 PLEKHA4 PLEKHA4 GNAL GNAL GNA14 GNA14 GNAQ GNAQ GNB4 GNB4 PTK2B PTK2B FYN FYN CTNNB1 CTNNB1 ESYT1 ESYT1 PTK6 PTK6 SRMS SRMS FGR FGR JUP JUP CDH24 CDH24 SYAP1 SYAP1 CDH26 CDH26 CRKL CRKL PICALM PICALM CTNND1 CTNND1 CDHR2 CDHR2 LOC102266153 LOC102266153 TGM3 TGM3 ENSBMUP00000026331 ENSBMUP00000026331 GNA12 GNA12 KRAS KRAS ESYT2 ESYT2 AAK1 AAK1 RGS1 RGS1 TNK2 TNK2 FERMT2 FERMT2 GNAT1 GNAT1 GNAI2 GNAI2 EPN3 EPN3 GNAO1 GNAO1 YES1 YES1 USP8 USP8 SLA SLA SNX18 SNX18 GNG3 GNG3 STOML2 STOML2 GNG13 GNG13 GNB1 GNB1 RACGAP1 RACGAP1 OSBPL2 OSBPL2 GNG5 GNG5 ENSBMUP00000032610 ENSBMUP00000032610 SNAP25 SNAP25 S100A10 S100A10 CDH2 CDH2 CDH12 CDH12 ZAP70 ZAP70 ST14 ST14 GNA13 GNA13 ENSBMUP00000034400 ENSBMUP00000034400 CDH13 CDH13 CYLD CYLD CDK16 CDK16 NUMA1 NUMA1 S100A6 S100A6 STYK1 STYK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APCAdenomatous polyposis coli protein. (2879 aa)
KCNAB2Voltage-gated potassium channel subunit beta-2. (415 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
SRCTyrosine-protein kinase. (559 aa)
GNAT3Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
GNAI1Guanine nucleotide-binding protein G(i) subunit alpha. (354 aa)
FCN1Ficolin-2. (329 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (460 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (296 aa)
ENSBMUP00000002129annotation not available (169 aa)
SNX9Sorting nexin-9. (600 aa)
STAC2SH3 and cysteine-rich domain-containing protein 2. (411 aa)
GNAZGuanine nucleotide-binding protein G(z) subunit alpha. (350 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)
CDH3Cadherin 3. (785 aa)
BLKTyrosine-protein kinase. (524 aa)
CDH17Cadherin-17. (832 aa)
LOC102269855Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
SYTL3Synaptotagmin-like protein 3. (609 aa)
PLGPlasminogen; Belongs to the peptidase S1 family. (805 aa)
GNAT2Guanine nucleotide-binding protein G(T) subunit alpha-2. (354 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
APC2Adenomatous polyposis coli protein 2. (2316 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11. (73 aa)
CTNNA2Catenin alpha-2. (953 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (941 aa)
MFGE8Lactadherin. (430 aa)
KCNIP1Kv channel-interacting protein 1. (207 aa)
DLG4Discs large MAGUK scaffold protein 4. (769 aa)
FRKTyrosine-protein kinase. (515 aa)
SNX5Sorting nexin-5/6/32. (401 aa)
ALOX15Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
CDH16Cadherin-16. (829 aa)
CDH19Cadherin-19; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
ENSBMUP00000006446annotation not available (314 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
TFTransferrin isoform X1; Belongs to the transferrin family. (704 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
CDH10Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
CDH22Cadherin 22. (773 aa)
GRAMD1AGRAM domain-containing protein 1A. (808 aa)
CDH11Cadherin-11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (659 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
ESYT3Extended synaptotagmin-3. (870 aa)
M91_02967Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
M91_13582Phosphatidylinositol-binding clathrin assembly protein. (275 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1627 aa)
GRAMD2AGRAM domain containing 2. (348 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (814 aa)
HIP1Huntingtin-interacting protein 1. (1037 aa)
MYZAPUncharacterized protein. (463 aa)
CDH4Cadherin-4; Cadherins are calcium-dependent cell adhesion proteins. (879 aa)
ENSBMUP00000011477annotation not available (366 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (539 aa)
RS1Retinoschisin. (224 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CDH20Cadherin-20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (356 aa)
NUMBProtein numb-like protein. (653 aa)
SYKNon-specific protein-tyrosine kinase. (629 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (353 aa)
CDH8Cadherin-8; Cadherins are calcium-dependent cell adhesion proteins. (659 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102270606Cadherin-7. (340 aa)
SNAP91Clathrin coat assembly protein AP180. (905 aa)
USP50Putative ubiquitin carboxyl-terminal hydrolase 50; Belongs to the peptidase C19 family. (310 aa)
ANXA1Annexin. (346 aa)
ENSBMUP00000014874annotation not available (279 aa)
LYNTyrosine-protein kinase. (512 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (404 aa)
LOC102271265Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CDH6Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
DCHS1Protocadherin-16. (3296 aa)
CDH15Cadherin 15. (660 aa)
PTK2Focal adhesion kinase 1. (1065 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (369 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CDH18Cadherin-18; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CTNNA1Catenin alpha-1. (906 aa)
CYTH3Cytohesin-3. (399 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
RHOATransforming protein RhoA. (193 aa)
NPTX2Neuronal pentraxin-2. (431 aa)
HCKTyrosine-protein kinase. (524 aa)
CBY3Protein chibby-like protein 3. (149 aa)
CDH9Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
PLEKHA4Pleckstrin-like protein domain-containing family A member 4. (780 aa)
GNALGuanine nucleotide-binding protein G(olf) subunit alpha. (135 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (355 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PTK2BProtein-tyrosine kinase 2-beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FYNTyrosine-protein kinase. (537 aa)
CTNNB1Catenin beta-1. (781 aa)
ESYT1Extended synaptotagmin-1. (1116 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SRMSTyrosine-protein kinase. (497 aa)
FGRTyrosine-protein kinase. (527 aa)
JUPJunction plakoglobin. (745 aa)
CDH24Cadherin-24; Cadherins are calcium-dependent cell adhesion proteins. (781 aa)
SYAP1Synapse-associated protein 1. (358 aa)
CDH26Cadherin-like protein 26. (805 aa)
CRKLCrk-like protein. (302 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein. (653 aa)
CTNND1Catenin delta-1. (998 aa)
CDHR2Cadherin-related family member 2. (1310 aa)
LOC102266153Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (394 aa)
TGM3Protein-glutamine gamma-glutamyltransferase E. (690 aa)
ENSBMUP00000026331annotation not available (63 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (291 aa)
KRASGTPase KRas. (189 aa)
ESYT2Extended synaptotagmin-2. (897 aa)
AAK1AP2-associated protein kinase 1. (1297 aa)
RGS1Regulator of G-protein signaling 1. (209 aa)
TNK2Activated CDC42 kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1034 aa)
FERMT2Fermitin family-like protein 2. (727 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
EPN3Epsin 3. (609 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
YES1Tyrosine-protein kinase. (543 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8. (1083 aa)
SLASrc like adaptor. (276 aa)
SNX18Sorting nexin-18. (678 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
STOML2Stomatin-like protein 2. (356 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
RACGAP1Rac GTPase-activating protein 1. (632 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (480 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSBMUP00000032610annotation not available (66 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (97 aa)
CDH2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (821 aa)
CDH12Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
ZAP70Non-specific protein-tyrosine kinase. (617 aa)
ST14Suppressor of tumorigenicity 14 protein-like protein. (855 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
ENSBMUP00000034400annotation not available (112 aa)
CDH13Cadherin 13, H-cadherin. (660 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD. (956 aa)
CDK16Cell division protein kinase 16; Belongs to the protein kinase superfamily. (570 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2114 aa)
S100A6Protein S100; Belongs to the S-100 family. (96 aa)
STYK1Tyrosine-protein kinase STYK1. (427 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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