47 items (Bos mutus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMPD1	Sphingomyelin phosphodiesterase. (625 aa)
	NPPA	Atrial natriuretic factor. (188 aa)
	GBA	Glucosylceramidase. (536 aa)
	STK38	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
	DAB2IP	DAB2 interacting protein. (1119 aa)
	NUP62	Nucleoporin 62. (448 aa)
	DUSP10	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
	LAX1	Lymphocyte transmembrane adapter 1. (387 aa)
	CD300A	CD300a molecule. (165 aa)
	HYAL2	Hyaluronidase. (473 aa)
	SH2B3	SH2B adapter protein 3. (568 aa)
	SFRP1	Secreted frizzled-related protein 1. (314 aa)
	APOE	Apolipoprotein E. (326 aa)
	ENSBMUP00000026412	annotation not available (249 aa)
	CBLC	Signal transduction protein CBL-C. (488 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (456 aa)
	AIDA	Axin interactor, dorsalization-associated protein. (306 aa)
	SPRY4	Protein sprouty-like protein 4. (321 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta. (1220 aa)
	ADIPOQ	Adiponectin. (246 aa)
	DNAJA1	DnaJ-like protein subfamily A member 1. (397 aa)
	SPRY2	Protein sprouty-like protein 2. (315 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	PAQR3	Progestin and adipoQ receptor family member 3. (311 aa)
	RGS14	Regulator of G-protein signaling 14. (564 aa)
	SFRP2	Secreted frizzled-related protein 2. (294 aa)
	DUSP16	Dual specificity phosphatase 16. (661 aa)
	SORL1	Sortilin related receptor 1. (2123 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type 6. (597 aa)
	SPRY3	Protein sprouty-like protein 3. (288 aa)
	INPP5K	Inositol polyphosphate 5-phosphatase K. (489 aa)
	NF1	Neurofibromin. (2848 aa)
	IRAK3	Interleukin 1 receptor associated kinase 3. (580 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type 1. (429 aa)
	DEFB114	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (65 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
	BMP2	Bone morphogenetic protein 2. (380 aa)
	TMEM130	Transmembrane protein 130. (410 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SPRY1	Protein sprouty-like protein 1. (319 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	DUSP7	Dual specificity protein phosphatase 7. (381 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
	CDK5RAP3	CDK5 regulatory subunit associated protein 3. (505 aa)
	DUSP1	Dual specificity protein phosphatase 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (348 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	APOE	ENSBMUP00000024103	ENSBMUP00000026490	Adiponectin.	Apolipoprotein E.	0.469
ADIPOQ	CAV1	ENSBMUP00000024103	ENSBMUP00000018309	Adiponectin.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.439
ADIPOQ	PAQR3	ENSBMUP00000024103	ENSBMUP00000021984	Adiponectin.	Progestin and adipoQ receptor family member 3.	0.535
AGT	APOE	ENSBMUP00000009074	ENSBMUP00000026490	Angiotensinogen; Belongs to the serpin family.	Apolipoprotein E.	0.468
AGT	NPPA	ENSBMUP00000009074	ENSBMUP00000016910	Angiotensinogen; Belongs to the serpin family.	Atrial natriuretic factor.	0.626
APOE	ADIPOQ	ENSBMUP00000026490	ENSBMUP00000024103	Apolipoprotein E.	Adiponectin.	0.469
APOE	AGT	ENSBMUP00000026490	ENSBMUP00000009074	Apolipoprotein E.	Angiotensinogen; Belongs to the serpin family.	0.468
APOE	CAV1	ENSBMUP00000026490	ENSBMUP00000018309	Apolipoprotein E.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.615
APOE	HMGCR	ENSBMUP00000026490	ENSBMUP00000015988	Apolipoprotein E.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.531
APOE	SORL1	ENSBMUP00000026490	ENSBMUP00000012464	Apolipoprotein E.	Sortilin related receptor 1.	0.655
BMP2	BMP4	ENSBMUP00000020594	ENSBMUP00000019052	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.929
BMP2	BMP7	ENSBMUP00000020594	ENSBMUP00000022105	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.664
BMP4	BMP2	ENSBMUP00000019052	ENSBMUP00000020594	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.929
BMP4	BMP7	ENSBMUP00000019052	ENSBMUP00000022105	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.803
BMP4	SPRY2	ENSBMUP00000019052	ENSBMUP00000022253	Bone morphogenetic protein 4.	Protein sprouty-like protein 2.	0.440
BMP7	BMP2	ENSBMUP00000022105	ENSBMUP00000020594	Bone morphogenetic protein 7.	Bone morphogenetic protein 2.	0.664
BMP7	BMP4	ENSBMUP00000022105	ENSBMUP00000019052	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.803
CAV1	ADIPOQ	ENSBMUP00000018309	ENSBMUP00000024103	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Adiponectin.	0.439
CAV1	APOE	ENSBMUP00000018309	ENSBMUP00000026490	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein E.	0.615
CAV1	CAV3	ENSBMUP00000018309	ENSBMUP00000015905	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.959