STRINGSTRING
GPR143 GPR143 PLCH1 PLCH1 EXOC1 EXOC1 INPP5F INPP5F PIK3CG PIK3CG PRR5L PRR5L KBTBD2 KBTBD2 PIK3R1 PIK3R1 IGF1 IGF1 PIK3C2A PIK3C2A CD28 CD28 PI4KA PI4KA PIRT PIRT PLCL2 PLCL2 PLCB1 PLCB1 PIK3C3 PIK3C3 PREX2 PREX2 PLCH2 PLCH2 PI4KB PI4KB OGT OGT PIK3R2 PIK3R2 PLCD4 PLCD4 HTR2B HTR2B AKT1 AKT1 RPS6KB1 RPS6KB1 PIK3C2G PIK3C2G PLCZ1 PLCZ1 IGF1R IGF1R EDN1 EDN1 PPARD PPARD ERBB2 ERBB2 EZR EZR PIK3CD PIK3CD PLCD3 PLCD3 PLCL1 PLCL1 PLCB2 PLCB2 GATA3 GATA3 NYAP1 NYAP1 PRR5 PRR5 ARHGAP8 ARHGAP8 C1QBP C1QBP KCNH1 KCNH1 PTEN PTEN PIK3CB PIK3CB ENSBMUP00000013218 ENSBMUP00000013218 PITPNM3 PITPNM3 PLCB4 PLCB4 NF1 NF1 CA8 CA8 PDGFRB PDGFRB ZFP36L1 ZFP36L1 HTR2A HTR2A IRS1 IRS1 PITPNM2 PITPNM2 PLEKHA1 PLEKHA1 SIRT2 SIRT2 PLCB3 PLCB3 CSF1R CSF1R PDGFRA PDGFRA PEAR1 PEAR1 PIK3CA PIK3CA SERPINA12 SERPINA12 ERBB3 ERBB3 PTAFR PTAFR LOC102284058 LOC102284058 PLCE1 PLCE1 PIK3C2B PIK3C2B LOC102287125 LOC102287125 ENSBMUP00000024422 ENSBMUP00000024422 PLCD1 PLCD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR143G-protein coupled receptor 143. (304 aa)
PLCH1Phosphatidylinositol phospholipase C, eta. (1688 aa)
EXOC1Exocyst complex component 1. (894 aa)
INPP5FPhosphatidylinositide phosphatase SAC2. (1133 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1104 aa)
PRR5LProline rich 5 like. (368 aa)
KBTBD2Kelch repeat and BTB domain-containing protein 2. (623 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
IGF1Insulin-like growth factor I. (194 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha. (1688 aa)
CD28T-cell-specific surface glycoprotein CD28. (265 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2102 aa)
PIRTPhosphoinositide-interacting protein. (138 aa)
PLCL2Phosphoinositide phospholipase C. (1001 aa)
PLCB1Phosphoinositide phospholipase C. (1183 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
PREX2Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein. (1604 aa)
PLCH2Phosphatidylinositol phospholipase C, eta. (1456 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (801 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1046 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
PLCD4Phosphoinositide phospholipase C. (791 aa)
HTR2B5-hydroxytryptamine receptor 2B. (538 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1; Belongs to the protein kinase superfamily. (525 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma. (230 aa)
PLCZ1Phosphoinositide phospholipase C. (637 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
EDN1Endothelin-1. (202 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
ERBB2Erb-b2 receptor tyrosine kinase 2. (1379 aa)
EZREzrin. (659 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta. (1044 aa)
PLCD3Phosphoinositide phospholipase C. (783 aa)
PLCL1Phosphoinositide phospholipase C. (1018 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
NYAP1Uncharacterized protein. (607 aa)
PRR5Proline rich 5. (348 aa)
ARHGAP8Rho GTPase-activating protein 8. (306 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (177 aa)
KCNH1Potassium voltage-gated channel subfamily H member 1. (987 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
ENSBMUP00000013218annotation not available (92 aa)
PITPNM3Membrane-associated phosphatidylinositol transfer protein 3. (1153 aa)
PLCB4Phosphoinositide phospholipase C. (1075 aa)
NF1Neurofibromin. (2848 aa)
CA8Carbonic anhydrase-related protein; Belongs to the alpha-carbonic anhydrase family. (290 aa)
PDGFRBBeta-type platelet-derived growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1103 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1. (338 aa)
HTR2A5-hydroxytryptamine receptor 2A. (493 aa)
IRS1Insulin receptor substrate 1. (1237 aa)
PITPNM2Membrane-associated phosphatidylinositol transfer protein 2. (1297 aa)
PLEKHA1Pleckstrin-like protein domain-containing family A member 1. (404 aa)
SIRT2NAD-dependent deacetylase sirtuin-2. (353 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (958 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1040 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
SERPINA12Serpin A12; Belongs to the serpin family. (412 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1336 aa)
PTAFRPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LOC102284058Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2. (409 aa)
PLCE1Phosphoinositide phospholipase C. (1785 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
LOC102287125Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (585 aa)
ENSBMUP00000024422annotation not available (88 aa)
PLCD1Phosphoinositide phospholipase C. (663 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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