(16 nodes) Protein localization to chromosome, telomeric region network (Bos mutus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TERF2IP	Telomeric repeat-binding factor 2-interacting protein 1. (399 aa)
	LOC102280639	Zinc finger protein 827. (755 aa)
	TINF2	TERF1-interacting nuclear factor 2. (463 aa)
	TNKS2	Poly [ADP-ribose] polymerase. (1166 aa)
	ATR	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2644 aa)
	M91_06823	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1232 aa)
	NABP2	Nucleic acid binding protein 2. (252 aa)
	ATRX	Transcriptional regulator ATRX. (2479 aa)
	POT1	Protection of telomeres protein 1. (473 aa)
	BRCA2	Breast cancer 2 susceptibility protein. (3374 aa)
	TPP1	Tripeptidyl-peptidase 1. (572 aa)
	TNKS	Poly [ADP-ribose] polymerase. (1327 aa)
	ZNF827	RE1-silencing transcription factor. (653 aa)
	ACD	Adrenocortical dysplasia protein-like protein. (455 aa)
	PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1. (309 aa)
	TERF2	Telomeric repeat-binding factor 2. (540 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACD	ATRX	ENSBMUP00000004402	ENSBMUP00000022747	Adrenocortical dysplasia protein-like protein.	Transcriptional regulator ATRX.	0.404
ACD	M91_06823	ENSBMUP00000004402	ENSBMUP00000026528	Adrenocortical dysplasia protein-like protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.871
ACD	POT1	ENSBMUP00000004402	ENSBMUP00000022570	Adrenocortical dysplasia protein-like protein.	Protection of telomeres protein 1.	0.997
ACD	TERF2	ENSBMUP00000004402	ENSBMUP00000001761	Adrenocortical dysplasia protein-like protein.	Telomeric repeat-binding factor 2.	0.980
ACD	TERF2IP	ENSBMUP00000004402	ENSBMUP00000029199	Adrenocortical dysplasia protein-like protein.	Telomeric repeat-binding factor 2-interacting protein 1.	0.983
ACD	TINF2	ENSBMUP00000004402	ENSBMUP00000033472	Adrenocortical dysplasia protein-like protein.	TERF1-interacting nuclear factor 2.	0.997
ATR	BRCA2	ENSBMUP00000027316	ENSBMUP00000018023	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	Breast cancer 2 susceptibility protein.	0.447
ATR	M91_06823	ENSBMUP00000027316	ENSBMUP00000026528	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.416
ATRX	ACD	ENSBMUP00000022747	ENSBMUP00000004402	Transcriptional regulator ATRX.	Adrenocortical dysplasia protein-like protein.	0.404
ATRX	M91_06823	ENSBMUP00000022747	ENSBMUP00000026528	Transcriptional regulator ATRX.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.529
ATRX	POT1	ENSBMUP00000022747	ENSBMUP00000022570	Transcriptional regulator ATRX.	Protection of telomeres protein 1.	0.483
ATRX	TERF2	ENSBMUP00000022747	ENSBMUP00000001761	Transcriptional regulator ATRX.	Telomeric repeat-binding factor 2.	0.486
ATRX	TERF2IP	ENSBMUP00000022747	ENSBMUP00000029199	Transcriptional regulator ATRX.	Telomeric repeat-binding factor 2-interacting protein 1.	0.423
ATRX	TINF2	ENSBMUP00000022747	ENSBMUP00000033472	Transcriptional regulator ATRX.	TERF1-interacting nuclear factor 2.	0.501
BRCA2	ATR	ENSBMUP00000018023	ENSBMUP00000027316	Breast cancer 2 susceptibility protein.	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	0.447
LOC102280639	TERF2	ENSBMUP00000033709	ENSBMUP00000001761	Zinc finger protein 827.	Telomeric repeat-binding factor 2.	0.410
LOC102280639	ZNF827	ENSBMUP00000033709	ENSBMUP00000008095	Zinc finger protein 827.	RE1-silencing transcription factor.	0.900
M91_06823	ACD	ENSBMUP00000026528	ENSBMUP00000004402	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Adrenocortical dysplasia protein-like protein.	0.871
M91_06823	ATR	ENSBMUP00000026528	ENSBMUP00000027316	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	0.416
M91_06823	ATRX	ENSBMUP00000026528	ENSBMUP00000022747	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Transcriptional regulator ATRX.	0.529