(39 nodes) SAGA-type complex network (Bos mutus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSBMUP00000024454	annotation not available (89 aa)
	TAF9B	Transcription initiation factor TFIID subunit 9B. (254 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	KAT2A	Histone acetyltransferase KAT2A. (837 aa)
	USP22	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (468 aa)
	DR1	Protein Dr1. (176 aa)
	TRRAP	Transformation/transcription domain associated protein. (3848 aa)
	SUPT20H	Protein FAM48A. (817 aa)
	POLE4	DNA polymerase epsilon subunit 4. (117 aa)
	M91_11796	TFIID_20kDa domain-containing protein. (199 aa)
	TAF10	Transcription initiation factor TFIID subunit 10. (218 aa)
	TADA3	Transcriptional adapter 3. (432 aa)
	SUPT3H	Transcription initiation protein SPT3-like protein. (316 aa)
	SUPT7L	STAGA complex 65 subunit gamma. (412 aa)
	KAT14	Cysteine-rich protein 2-binding protein. (797 aa)
	KAT2B	Histone acetyltransferase KAT2B. (832 aa)
	TADA2A	Transcriptional adapter. (443 aa)
	ENSBMUP00000008022	annotation not available (280 aa)
	TAF5L	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L. (589 aa)
	TAF4	Transcription initiation factor TFIID subunit 4. (720 aa)
	TADA1	Transcriptional adapter 1. (193 aa)
	SGF29	SAGA-associated factor 29-like protein. (293 aa)
	M91_02665	Transcriptional adapter. (334 aa)
	TAF2	Transcription initiation factor TFIID subunit 2. (1251 aa)
	TAF6	Transcription initiation factor TFIID subunit 6. (678 aa)
	TAF6L	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L. (626 aa)
	POLE3	DNA polymerase epsilon subunit 3. (145 aa)
	M91_09432	Transcription initiation factor TFIID subunit 9. (286 aa)
	M91_18193	Uncharacterized protein. (553 aa)
	YEATS2	YEATS domain-containing protein 2. (1411 aa)
	ZZZ3	ZZ-type zinc finger-containing protein 3. (903 aa)
	ATXN7L3	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (407 aa)
	LOC102273301	Mucin-2-like. (769 aa)
	WDR5	COMPASS component SWD3. (345 aa)
	TAF5	Transcription initiation factor TFIID subunit 5. (796 aa)
	ENY2	Enhancer of yellow 2 transcription factor-like protein. (101 aa)
	TAF12	Transcription initiation factor TFIID subunit 12. (204 aa)
	MBIP	MAP3K12-binding inhibitory protein 1. (344 aa)
	USP27X	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN7L3	ENSBMUP00000008022	ENSBMUP00000025962	ENSBMUP00000008022	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	annotation not available	0.767
ATXN7L3	ENSBMUP00000024454	ENSBMUP00000025962	ENSBMUP00000024454	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	annotation not available	0.565
ATXN7L3	ENY2	ENSBMUP00000025962	ENSBMUP00000001431	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Enhancer of yellow 2 transcription factor-like protein.	0.981
ATXN7L3	KAT2A	ENSBMUP00000025962	ENSBMUP00000022169	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Histone acetyltransferase KAT2A.	0.707
ATXN7L3	KAT2B	ENSBMUP00000025962	ENSBMUP00000011741	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Histone acetyltransferase KAT2B.	0.707
ATXN7L3	M91_02665	ENSBMUP00000025962	ENSBMUP00000035916	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adapter.	0.844
ATXN7L3	M91_09432	ENSBMUP00000025962	ENSBMUP00000031016	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 9.	0.527
ATXN7L3	M91_11796	ENSBMUP00000025962	ENSBMUP00000017289	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	TFIID_20kDa domain-containing protein.	0.769
ATXN7L3	SGF29	ENSBMUP00000025962	ENSBMUP00000035437	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	SAGA-associated factor 29-like protein.	0.891
ATXN7L3	SUPT3H	ENSBMUP00000025962	ENSBMUP00000014996	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation protein SPT3-like protein.	0.809
ATXN7L3	TADA1	ENSBMUP00000025962	ENSBMUP00000035767	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adapter 1.	0.966
ATXN7L3	TADA2A	ENSBMUP00000025962	ENSBMUP00000006964	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adapter.	0.844
ATXN7L3	TADA3	ENSBMUP00000025962	ENSBMUP00000015083	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adapter 3.	0.840
ATXN7L3	TAF10	ENSBMUP00000025962	ENSBMUP00000016948	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 10.	0.759
ATXN7L3	TAF12	ENSBMUP00000025962	ENSBMUP00000002690	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 12.	0.769
ATXN7L3	TAF5	ENSBMUP00000025962	ENSBMUP00000001194	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 5.	0.565
ATXN7L3	TAF5L	ENSBMUP00000025962	ENSBMUP00000011146	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L.	0.709
ATXN7L3	TAF6	ENSBMUP00000025962	ENSBMUP00000031776	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 6.	0.654
ATXN7L3	TAF6L	ENSBMUP00000025962	ENSBMUP00000031457	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L.	0.769
ATXN7L3	TAF9B	ENSBMUP00000025962	ENSBMUP00000022435	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 9B.	0.527