STRINGSTRING
TFAP2B TFAP2B ENSBMUP00000000260 ENSBMUP00000000260 ENSBMUP00000000278 ENSBMUP00000000278 GATA3 GATA3 WNT9B WNT9B CTNNBIP1 CTNNBIP1 WNT11 WNT11 ENSBMUP00000003175 ENSBMUP00000003175 FGF8 FGF8 NOTCH1 NOTCH1 GZF1 GZF1 LZTS2 LZTS2 BCL2 BCL2 PAX2 PAX2 UMOD UMOD LHX1 LHX1 GPC3 GPC3 OSR1 OSR1 HNF1B HNF1B KIF26B KIF26B GDNF GDNF WT1 WT1 TCF21 TCF21 PAX8 PAX8 TACSTD2 TACSTD2 AQP1 AQP1 IRX3 IRX3 DLG2 DLG2 CALB1 CALB1 HES1 HES1 NOTCH2 NOTCH2 AQP11 AQP11 AHI1 AHI1 DCHS1 DCHS1 ILK ILK HS3ST3B1 HS3ST3B1 HEYL HEYL FAT4 FAT4 FGF2 FGF2 BMP4 BMP4 COMMD5 COMMD5 GREM1 GREM1 FMN1 FMN1 TMEM59L TMEM59L LOC102275627 LOC102275627 LOC102265716 LOC102265716 BMP2 BMP2 PTCH1 PTCH1 MEF2C MEF2C PKD1 PKD1 SHH SHH CTNNB1 CTNNB1 HS2ST1 HS2ST1 EYA1 EYA1 ADAMTS16 ADAMTS16 FGF1 FGF1 M91_06811 M91_06811 LOC102268721 LOC102268721 PKD2 PKD2 M91_18522 M91_18522 DLG1 DLG1 NPNT NPNT GREB1L GREB1L WNT1 WNT1 M91_10894 M91_10894 SOX8 SOX8 LAMA5 LAMA5 SMAD4 SMAD4 LGR4 LGR4 JAG1 JAG1 SIX1 SIX1 KLHL3 KLHL3 WNT6 WNT6 DLL1 DLL1 MTSS1 MTSS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFAP2BTranscription factor AP-2-beta. (460 aa)
ENSBMUP00000000260annotation not available (62 aa)
ENSBMUP00000000278annotation not available (53 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (337 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSBMUP00000003175annotation not available (150 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
NOTCH1Uncharacterized protein. (2349 aa)
GZF1GDNF-inducible zinc finger protein 1. (714 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (633 aa)
BCL2Apoptosis regulator Bcl-2. (225 aa)
PAX2Paired box protein Pax-2. (417 aa)
UMODUromodulin. (643 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
OSR1Odd-skipped related transciption factor 1. (267 aa)
HNF1BHepatocyte nuclear factor 1-beta. (558 aa)
KIF26BKinesin-like protein KIF26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1783 aa)
GDNFGlial cell line-derived neurotrophic factor. (185 aa)
WT1WT1 transcription factor. (518 aa)
TCF21Transcription factor 21. (179 aa)
PAX8Paired box protein Pax-8. (457 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (319 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
IRX3Iroquois homeobox 3. (498 aa)
DLG2Discs large MAGUK scaffold protein 2. (348 aa)
CALB1Calbindin. (261 aa)
HES1Transcription factor HES-1. (269 aa)
NOTCH2Uncharacterized protein. (2471 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
AHI1Jouberin. (1177 aa)
DCHS1Protocadherin-16. (3296 aa)
ILKIntegrin-linked protein kinase. (452 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (458 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein. (301 aa)
FAT4Protocadherin Fat 4. (4981 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
COMMD5COMM domain-containing protein 5. (224 aa)
GREM1Gremlin. (240 aa)
FMN1Formin-1. (1184 aa)
TMEM59LTransmembrane protein 59-like protein. (349 aa)
LOC102275627Serine/threonine-protein kinase WNK4. (846 aa)
LOC102265716Serine/threonine-protein kinase WNK4-like. (314 aa)
BMP2Bone morphogenetic protein 2. (380 aa)
PTCH1Protein patched-like protein 1. (1459 aa)
MEF2CMyocyte-specific enhancer factor 2C. (483 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4168 aa)
SHHSonic hedgehog protein. (453 aa)
CTNNB1Catenin beta-1. (781 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1. (356 aa)
EYA1EYA transcriptional coactivator and phosphatase 1. (616 aa)
ADAMTS16A disintegrin and metalloproteinase with thrombospondin motifs 16. (1230 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (195 aa)
M91_06811Iroquois-class homeodomain protein IRX-1. (553 aa)
LOC102268721Transcriptional activator GLI3-like. (535 aa)
PKD2Polycystin-2. (970 aa)
M91_18522Uncharacterized protein. (286 aa)
DLG1Disks large-like protein 1; Belongs to the MAGUK family. (939 aa)
NPNTNephronectin. (632 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1919 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
M91_10894Transcription factor HES-5. (196 aa)
SOX8Transcription factor SOX-8. (472 aa)
LAMA5Laminin subunit alpha-5. (3660 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (886 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1177 aa)
SIX1Homeobox protein SIX1. (284 aa)
KLHL3Kelch-like protein 3. (590 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (687 aa)
MTSS1Metastasis suppressor protein 1. (762 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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