STRINGSTRING
LOC102275979 LOC102275979 KCNA5 KCNA5 CACNA1D CACNA1D LOC102273260 LOC102273260 KCNQ1 KCNQ1 ENSBMUP00000032222 ENSBMUP00000032222 KCNJ2 KCNJ2 LOC102286497 LOC102286497 LOC102275069 LOC102275069 DSP DSP CACNA2D1 CACNA2D1 SCN3B SCN3B SCN5A SCN5A AKAP9 AKAP9 LOC102285465 LOC102285465 KCNE3 KCNE3 KCNJ5 KCNJ5 KCNE4 KCNE4 PKP2 PKP2 ISL1 ISL1 SCN1B SCN1B CACNA1C-2 CACNA1C-2 CACNA1C CACNA1C KCNE2 KCNE2 CACNB2 CACNB2 KCND3 KCND3 DSC2 DSC2 DSG2 DSG2 SCN2B SCN2B SCN4B SCN4B HCN4 HCN4 CAV1 CAV1 KCNE5 KCNE5 JUP JUP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102275979Transient receptor putative cation channel subfamily M member 4. (671 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (565 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
LOC102273260Potassium voltage-gated channel subfamily H member 6. (502 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (676 aa)
ENSBMUP00000032222Catenin alpha-2-like. (183 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
LOC102286497Potassium voltage-gated channel subfamily E member 1. (131 aa)
LOC102275069Catenin alpha-3. (391 aa)
DSPDesmoplakin. (2843 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1103 aa)
SCN3BSodium channel subunit beta-3. (215 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2021 aa)
AKAP9A-kinase anchoring protein 9. (3895 aa)
LOC102285465Transient receptor potential cation channel subfamily M member 4-like. (376 aa)
KCNE3Potassium voltage-gated channel subfamily E member 3. (99 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
KCNE4Potassium voltage-gated channel subfamily E member 4. (168 aa)
PKP2Plakophilin-2. (843 aa)
ISL1Insulin enhancer protein ISL-1. (349 aa)
SCN1BSodium channel subunit beta-1. (207 aa)
CACNA1C-2Voltage-dependent calcium channel L type alpha-1C. (1249 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (841 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2. (658 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
DSC2Desmocollin-2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (898 aa)
DSG2Desmoglein-2. (1121 aa)
SCN2BSodium channel subunit beta-2. (215 aa)
SCN4BSodium channel subunit beta-4. (228 aa)
HCN4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1097 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
KCNE5Potassium voltage-gated channel subfamily E member 1-like protein. (146 aa)
JUPJunction plakoglobin. (745 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.