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TRMT61B TRMT61B TYW5 TYW5 NARS1 NARS1 RPP25 RPP25 TRMT10B TRMT10B METTL8 METTL8 TARBP1 TARBP1 RARS1 RARS1 DUS2 DUS2 TRMO TRMO LOC102274921 LOC102274921 PRORP PRORP SARS1 SARS1 RPP14 RPP14 QTRT1 QTRT1 DTD1 DTD1 SMIM26 SMIM26 PUS10 PUS10 PSTK PSTK TRMT2A TRMT2A MTFMT MTFMT WARS1 WARS1 PTRH2 PTRH2 TRMT13 TRMT13 YARS2 YARS2 DARS1 DARS1 FTSJ1 FTSJ1 DARS2 DARS2 GATB GATB IARS2 IARS2 EPRS1 EPRS1 THUMPD2 THUMPD2 TARS1 TARS1 POP4 POP4 DTWD2 DTWD2 TSEN34 TSEN34 RPP21 RPP21 DUS4L DUS4L VARS2 VARS2 LARS1 LARS1 LARS2 LARS2 MRPL58 MRPL58 TRDMT1 TRDMT1 TRMT10A TRMT10A IARS1 IARS1 SEPSECS SEPSECS ENSBMUP00000011823 ENSBMUP00000011823 NSUN6 NSUN6 YARS1 YARS1 TSEN54 TSEN54 PARS2 PARS2 TRMT9B TRMT9B LOC102280017 LOC102280017 CARS2 CARS2 MARS2 MARS2 TRMT10C TRMT10C FTO FTO GARS1 GARS1 QRSL1 QRSL1 ENSBMUP00000013938 ENSBMUP00000013938 METTL6 METTL6 PTRH1 PTRH1 M91_19109 M91_19109 TRMT44 TRMT44 ENSBMUP00000014714 ENSBMUP00000014714 AARS2 AARS2 LYRM9 LYRM9 THUMPD3 THUMPD3 RPP38 RPP38 NARS2 NARS2 DTD2 DTD2 WDR4 WDR4 WARS2 WARS2 RARS2 RARS2 CDKAL1 CDKAL1 TRMT11 TRMT11 COX16 COX16 TARS3 TARS3 ELAC2 ELAC2 DALRD3 DALRD3 QARS1 QARS1 SARS2 SARS2 VARS1 VARS1 TRPT1 TRPT1 FARSA FARSA TRMT1 TRMT1 NSUN3 NSUN3 LOC102281772 LOC102281772 HARS1 HARS1 TYW3 TYW3 QTRT2 QTRT2 HARS2 HARS2 LOC102265557 LOC102265557 SDAD1 SDAD1 ALKBH1 ALKBH1 POP7 POP7 SMIM36 SMIM36 LOC102264448 LOC102264448 FARS2 FARS2 RPP40 RPP40 TRMT61A TRMT61A GATC GATC POP5 POP5 PIGX PIGX TRMT1L TRMT1L RPP30 RPP30 KARS1 KARS1 ENSBMUP00000029771 ENSBMUP00000029771 LRRC47 LRRC47 AARS1 AARS1 POP1 POP1 DTWD1 DTWD1 TMEM179B TMEM179B TARS2 TARS2 BCDIN3D BCDIN3D TRIT1 TRIT1 ELAC1 ELAC1 CARS1 CARS1 PUSL1 PUSL1 TRMT12 TRMT12 EARS2 EARS2 NSUN2 NSUN2 METTL2A METTL2A FARSB FARSB TRMT5 TRMT5 METTL1 METTL1 MARS1 MARS1 DUS3L DUS3L DUS1L DUS1L PUS3 PUS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRMT61BPutative tRNA (Adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B. (496 aa)
TYW5JmjC domain-containing protein. (315 aa)
NARS1Asparaginyl-tRNA synthetase, cytoplasmic. (548 aa)
RPP25Ribonuclease P protein subunit p25. (199 aa)
TRMT10BRNA (Guanine-9-)-methyltransferase domain-containing protein 3. (316 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (407 aa)
TARBP1Putative methyltransferase TARBP1. (1602 aa)
RARS1Arginyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (660 aa)
DUS2tRNA-dihydrouridine synthase 2-like protein. (493 aa)
TRMONef-associated protein 1. (435 aa)
LOC102274921tRNA wybutosine-synthesizing protein 1-like protein. (731 aa)
PRORPMitochondrial ribonuclease P protein 3. (584 aa)
SARS1Seryl-tRNA synthetase, cytoplasmic. (514 aa)
RPP14Ribonuclease P protein subunit RPP14. (124 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (395 aa)
DTD1D-aminoacyl-tRNA deacylase. (309 aa)
SMIM26Uncharacterized protein. (90 aa)
PUS10Putative tRNA pseudouridine synthase Pus10. (532 aa)
PSTKL-seryl-tRNA(Sec) kinase. (358 aa)
TRMT2AtRNA (Uracil-5-)-methyltransferase-like protein A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (628 aa)
MTFMTMethionyl-tRNA formyltransferase, mitochondrial. (442 aa)
WARS1Tryptophanyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa)
PTRH2Peptidyl-tRNA hydrolase 2, mitochondrial. (179 aa)
TRMT13tRNA guanosine-2'-O-methyltransferase TRM13-like protein. (481 aa)
YARS2Tyrosine--tRNA ligase. (478 aa)
DARS1Aspartyl-tRNA synthetase, cytoplasmic. (501 aa)
FTSJ1Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (329 aa)
DARS2Aspartyl-tRNA synthetase, mitochondrial. (644 aa)
GATBGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (557 aa)
IARS2Isoleucyl-tRNA synthetase 2, mitochondrial. (1012 aa)
EPRS1Bifunctional glutamyl/prolyl-tRNA synthetase. (1508 aa)
THUMPD2THUMP domain-containing protein 2. (501 aa)
TARS1Threonyl-tRNA synthetase, cytoplasmic. (723 aa)
POP4Ribonuclease P protein subunit p29. (220 aa)
DTWD2DTW domain-containing protein 2. (298 aa)
TSEN34tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (312 aa)
RPP21Ribonuclease P protein subunit RPR2. (154 aa)
DUS4LtRNA-dihydrouridine synthase 4-like protein. (320 aa)
VARS2Valyl-tRNA synthetase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1060 aa)
LARS1Leucyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa)
LARS2Putative leucyl-tRNA synthetase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (825 aa)
MRPL58RF_PROK_I domain-containing protein. (206 aa)
TRDMT1tRNA (Cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (391 aa)
TRMT10ARNA (Guanine-9-)-methyltransferase domain-containing protein 2. (338 aa)
IARS1Isoleucyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa)
SEPSECSO-phosphoseryl-tRNA(Sec) selenium transferase. (263 aa)
ENSBMUP00000011823annotation not available (91 aa)
NSUN6Putative methyltransferase NSUN6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (470 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
TSEN54tRNA-splicing endonuclease subunit Sen54. (427 aa)
PARS2Putative prolyl-tRNA synthetase, mitochondrial. (488 aa)
TRMT9BPutative methyltransferase KIAA1456-like protein. (424 aa)
LOC102280017Alkylated DNA repair protein alkB homolog 8-like. (238 aa)
CARS2Cysteinyl-tRNA synthetase, mitochondrial. (560 aa)
MARS2Methionyl-tRNA synthetase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (582 aa)
TRMT10CMitochondrial ribonuclease P protein 1. (426 aa)
FTOAlpha-ketoglutarate-dependent dioxygenase FTO. (505 aa)
GARS1Glycyl-tRNA synthetase. (739 aa)
QRSL1Glutamyl-tRNA(Gln) amidotransferase subunit A-like protein. (526 aa)
ENSBMUP00000013938annotation not available (83 aa)
METTL6Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (307 aa)
PTRH1Putative peptidyl-tRNA hydrolase. (284 aa)
M91_19109Alkylated DNA repair protein alkB-like protein 8. (214 aa)
TRMT44Putative tRNA (Uracil-O(2)-)-methyltransferase. (399 aa)
ENSBMUP00000014714annotation not available (154 aa)
AARS2Alanyl-tRNA synthetase, mitochondrial. (983 aa)
LYRM9Uncharacterized protein; Belongs to the complex I LYR family. (172 aa)
THUMPD3THUMP domain-containing protein 3. (503 aa)
RPP38Ribonuclease P protein subunit p38. (282 aa)
NARS2Putative asparaginyl-tRNA synthetase, mitochondrial. (478 aa)
DTD2Putative D-tyrosyl-tRNA(Tyr) deacylase 2. (168 aa)
WDR4tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (453 aa)
WARS2Tryptophanyl-tRNA synthetase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
RARS2Putative arginyl-tRNA synthetase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (617 aa)
CDKAL1CDK5 regulatory subunit-associated protein 1-like 1. (98 aa)
TRMT11tRNA guanosine-2'-O-methyltransferase TRM11-like protein. (459 aa)
COX16Cytochrome c oxidase assembly protein COX16-like protein, mitochondrial. (110 aa)
TARS3Putative threonyl-tRNA synthetase 2, cytoplasmic. (731 aa)
ELAC2Zinc phosphodiesterase ELAC protein 2. (825 aa)
DALRD3DALR anticodon-binding domain-containing protein 3. (541 aa)
QARS1Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
SARS2Seryl-tRNA synthetase, mitochondrial. (518 aa)
VARS1Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1281 aa)
TRPT1tRNA 2'-phosphotransferase 1. (341 aa)
FARSAPhenylalanyl-tRNA synthetase alpha chain. (508 aa)
TRMT1N(2),N(2)-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (676 aa)
NSUN3Putative methyltransferase NSUN3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (340 aa)
LOC102281772PrdX-deacylase domain-containing protein 1. (266 aa)
HARS1Histidyl-tRNA synthetase, cytoplasmic. (509 aa)
TYW3tRNA wybutosine-synthesizing protein 3-like protein. (258 aa)
QTRT2Queuine tRNA-ribosyltransferase accessory subunit 2. (415 aa)
HARS2Putative histidyl-tRNA synthetase, mitochondrial. (540 aa)
LOC102265557TRAM domain-containing protein. (323 aa)
SDAD1Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (688 aa)
ALKBH1Alkylated DNA repair protein alkB-like protein 1. (389 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
SMIM36Small integral membrane protein 36. (93 aa)
LOC102264448Alanyl-tRNA editing protein Aarsd1. (412 aa)
FARS2Phenylalanyl-tRNA synthetase, mitochondrial. (446 aa)
RPP40Ribonuclease P protein subunit p40. (363 aa)
TRMT61AtRNA (Adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A. (300 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (204 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (170 aa)
PIGXPhosphatidylinositol-glycan biosynthesis class X protein. (276 aa)
TRMT1LTRM1-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (737 aa)
RPP30Ribonuclease P protein subunit p30. (268 aa)
KARS1Lysyl-tRNA synthetase, class II. (623 aa)
ENSBMUP00000029771annotation not available (100 aa)
LRRC47Leucine-rich repeat-containing protein 47. (580 aa)
AARS1Alanyl-tRNA synthetase, cytoplasmic; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (968 aa)
POP1Ribonucleases P/MRP protein subunit POP1. (1015 aa)
DTWD1DTW domain-containing protein 1. (301 aa)
TMEM179BTransmembrane protein 179B. (218 aa)
TARS2Threonyl-tRNA synthetase, mitochondrial. (721 aa)
BCDIN3DPutative methyltransferase BCDIN3D. (393 aa)
TRIT1tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (467 aa)
ELAC1Zinc phosphodiesterase ELAC protein 1. (363 aa)
CARS1Cysteinyl-tRNA synthetase. (831 aa)
PUSL1tRNA pseudouridine synthase. (287 aa)
TRMT12tRNA wybutosine-synthesizing protein 2-like protein. (462 aa)
EARS2Putative glutamyl-tRNA synthetase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (518 aa)
NSUN2tRNA (Cytosine-5-)-methyltransferase NSUN2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (840 aa)
METTL2AMethyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (378 aa)
FARSBPhenylalanyl-tRNA synthetase beta chain. (585 aa)
TRMT5tRNA (Guanine-N(1)-)-methyltransferase. (497 aa)
METTL1tRNA (guanine(46)-N(7))-methyltransferase. (277 aa)
MARS1Methionyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (906 aa)
DUS3LDihydrouridine synthase 3 like. (648 aa)
DUS1LtRNA-dihydrouridine synthase 1-like protein. (475 aa)
PUS3tRNA pseudouridine synthase 3. (481 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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