STRINGSTRING
LCP1 LCP1 MYO5B MYO5B DMTN DMTN RFLNA RFLNA ACTN1 ACTN1 RTKN RTKN GAS2L2 GAS2L2 ENSBMUP00000016777 ENSBMUP00000016777 ACTA1 ACTA1 GAS7 GAS7 CNN2 CNN2 ARPC4 ARPC4 COBL COBL XIRP2 XIRP2 LANCL3 LANCL3 SEPTIN12 SEPTIN12 TMOD2 TMOD2 TWF2 TWF2 M91_10188 M91_10188 TMSB15B TMSB15B LOC102277968 LOC102277968 M91_10202 M91_10202 ACTR3C ACTR3C ABL1 ABL1 MYO1E MYO1E MYO19 MYO19 ENSBMUP00000007775 ENSBMUP00000007775 CTTN CTTN SHROOM4 SHROOM4 MYO1G MYO1G ARPC5L ARPC5L MYH15 MYH15 LOC102264614 LOC102264614 ARPC3 ARPC3 CORO1C CORO1C GSN GSN ACTB ACTB ARPC5 ARPC5 ENSBMUP00000028992 ENSBMUP00000028992 TNNT2 TNNT2 MYLPF MYLPF ENSBMUP00000030166 ENSBMUP00000030166 DCTN5 DCTN5 LANCL2 LANCL2 DBNL DBNL ENSBMUP00000030852 ENSBMUP00000030852 ARPC1B ARPC1B KRT14 KRT14 SSMEM1 SSMEM1 SWAP70 SWAP70 ENSBMUP00000032122 ENSBMUP00000032122 CD2AP CD2AP DAAM2 DAAM2 TPM2 TPM2 MYO7A MYO7A TMOD4 TMOD4 SMTN SMTN SCIN SCIN MYO9B MYO9B MYADM MYADM MYO5A MYO5A MYL4 MYL4 ADD1 ADD1 AVIL AVIL FBLIM1 FBLIM1 MYO1F MYO1F RUFY4 RUFY4 ARPC2 ARPC2 MYO1A MYO1A SPATA3 SPATA3 DAB2 DAB2 BIN2 BIN2 FSCN2 FSCN2 C10orf90 C10orf90 ENSBMUP00000036125 ENSBMUP00000036125 ANLN ANLN FILIP1 FILIP1 ENSBMUP00000009000 ENSBMUP00000009000 P3H1 P3H1 PAICS PAICS ASAP1 ASAP1 HNRNPK HNRNPK CIB2 CIB2 TNNC1 TNNC1 DBN1 DBN1 NEBL NEBL TNNT3 TNNT3 SORBS1 SORBS1 ACTR2 ACTR2 TNNI3 TNNI3 TNNT1 TNNT1 LOC102266026 LOC102266026 TNNI2 TNNI2 ENSBMUP00000025741 ENSBMUP00000025741 RHOU RHOU DCTN4 DCTN4 WIPF1 WIPF1 PRRC2B PRRC2B CDC42EP3 CDC42EP3 PAWR PAWR APMAP APMAP WAS WAS MYH7B MYH7B RHOQ RHOQ HCLS1 HCLS1 FHL3 FHL3 CALD1 CALD1 TNNC2 TNNC2 MYO18A MYO18A SPATA17 SPATA17 BICD2 BICD2 PDCD6IP PDCD6IP CAPZA3 CAPZA3 ACTR3 ACTR3 FLNB FLNB SYNPO2 SYNPO2 AMOT AMOT M91_11552 M91_11552 LPXN LPXN ANKRD26 ANKRD26 AFAP1 AFAP1 CFL2 CFL2 CARMIL2 CARMIL2 CDC42BPB CDC42BPB MYH11 MYH11 FAM107A FAM107A M91_09989 M91_09989 MYL1 MYL1 TMOD1 TMOD1 WDR1 WDR1 GAS2 GAS2 CAPZA1 CAPZA1 DYNLL2 DYNLL2 PEAK1 PEAK1 POF1B POF1B SNX9 SNX9 ACTR10 ACTR10 MYL12A MYL12A DEF6 DEF6 ENSBMUP00000001590 ENSBMUP00000001590 ENSBMUP00000001481 ENSBMUP00000001481 MYL9 MYL9 DAAM1 DAAM1 MYO18B MYO18B SH3PXD2A SH3PXD2A M91_04522 M91_04522 ENSBMUP00000000849 ENSBMUP00000000849 BMF BMF GDPD2 GDPD2 M91_10244 M91_10244 TMOD3 TMOD3 H1-0 H1-0 TRIOBP TRIOBP ENSBMUP00000012720 ENSBMUP00000012720 TPM4 TPM4 M91_03330 M91_03330 M91_03329 M91_03329 ABLIM1 ABLIM1 KNCN KNCN TNNI1 TNNI1 DCTN3 DCTN3 DDX58 DDX58 LOC102268264 LOC102268264 ENSBMUP00000023658 ENSBMUP00000023658 MYH13 MYH13 ACKR2 ACKR2 NKX2-5 NKX2-5 MYO15A MYO15A MYL3 MYL3 SH3PXD2B SH3PXD2B MOK MOK SPTB SPTB MYL6B MYL6B ACTN2 ACTN2 M91_03436 M91_03436 MPRIP MPRIP MYH3 MYH3 SPTA1 SPTA1 KLHL2 KLHL2 ENSBMUP00000020973 ENSBMUP00000020973 LIMCH1 LIMCH1 ENSBMUP00000020839 ENSBMUP00000020839 CCDC88A CCDC88A ENSBMUP00000020678 ENSBMUP00000020678 KIF9 KIF9 WASL WASL IQGAP3 IQGAP3 FMN1 FMN1 ARPC1A ARPC1A UBR7 UBR7 ENSBMUP00000019939 ENSBMUP00000019939 FERMT3 FERMT3 AFAP1L1 AFAP1L1 ABLIM3 ABLIM3 DCTN6 DCTN6 PDLIM4 PDLIM4 ABL2 ABL2 CAPZA2 CAPZA2 CAPZB CAPZB ZYX ZYX PEAK3 PEAK3 RFLNB RFLNB AUH AUH MYO1D MYO1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LCP1Lymphocyte cytosolic protein 1. (627 aa)
MYO5BMyosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1712 aa)
DMTNDematin. (405 aa)
RFLNAProtein FAM101A. (214 aa)
ACTN1Alpha-actinin-1. (964 aa)
RTKNRhotekin. (564 aa)
GAS2L2GAS2-like protein 2. (520 aa)
ENSBMUP00000016777annotation not available (190 aa)
ACTA1Actin, alpha 1, skeletal muscle. (377 aa)
GAS7Growth arrest-specific protein 7. (414 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (334 aa)
ARPC4Actin-related protein 2/3 complex subunit 4. (188 aa)
COBLProtein cordon-bleu. (807 aa)
XIRP2Xin actin-binding repeat-containing protein 2. (3393 aa)
LANCL3LanC-like protein 3. (420 aa)
SEPTIN12Septin-12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (333 aa)
TMOD2Tropomodulin-2. (351 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
M91_10188Uncharacterized protein. (302 aa)
TMSB15BThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
LOC102277968Myeloid-associated differentiation marker. (300 aa)
M91_10202Uncharacterized protein. (295 aa)
ACTR3CARP3 actin related protein 3 homolog B. (330 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
MYO1EMyosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
MYO19Myosin-XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (956 aa)
ENSBMUP00000007775annotation not available (113 aa)
CTTNSrc substrate cortactin. (536 aa)
SHROOM4Protein Shroom4. (1495 aa)
MYO1GMyosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (164 aa)
MYH15Myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1980 aa)
LOC102264614Myosin-11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1611 aa)
ARPC3Actin-related protein 2/3 complex subunit 3. (178 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (513 aa)
GSNGelsolin. (770 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ARPC5Actin related protein 2/3 complex, subunit 5. (151 aa)
ENSBMUP00000028992annotation not available (165 aa)
TNNT2Troponin T2, cardiac type. (307 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
ENSBMUP00000030166annotation not available (375 aa)
DCTN5Dynactin subunit 5. (182 aa)
LANCL2LanC-like protein 2. (452 aa)
DBNLDrebrin-like protein. (435 aa)
ENSBMUP00000030852Actin-related protein 2/3 complex subunit 1A-like. (176 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (365 aa)
KRT14Keratin, type I cytoskeletal 14; Belongs to the intermediate filament family. (469 aa)
SSMEM1Uncharacterized protein. (241 aa)
SWAP70Switch-associated protein 70. (585 aa)
ENSBMUP00000032122annotation not available (153 aa)
CD2APCD2-associated protein. (634 aa)
DAAM2Disheveled-associated activator of morphogenesis 2. (1076 aa)
TPM2Tropomyosin beta chain; Belongs to the tropomyosin family. (456 aa)
MYO7AMyosin-VIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2177 aa)
TMOD4Tropomodulin-4. (345 aa)
SMTNSmoothelin. (906 aa)
SCINAdseverin. (715 aa)
MYO9BMyosin-IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1664 aa)
MYADMMyeloid-associated differentiation marker. (322 aa)
MYO5AMyosin-Va; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1855 aa)
MYL4Myosin light chain 4. (216 aa)
ADD1Alpha-adducin. (723 aa)
AVILAdvillin. (816 aa)
FBLIM1Filamin-binding LIM protein 1. (378 aa)
MYO1FMyosin-If; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
RUFY4RUN and FYVE domain-containing protein 4. (571 aa)
ARPC2Actin related protein 2/3 complex, subunit 2. (413 aa)
MYO1AMyosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
SPATA3Spermatogenesis-associated protein 3. (193 aa)
DAB2Disabled-like protein 2. (768 aa)
BIN2Bridging integrator 2. (519 aa)
FSCN2Fascin actin-bundling protein 2, retinal. (483 aa)
C10orf90Uncharacterized protein. (697 aa)
ENSBMUP00000036125annotation not available (94 aa)
ANLNActin-binding protein anillin. (1130 aa)
FILIP1Filamin-A-interacting protein 1. (1177 aa)
ENSBMUP00000009000annotation not available (148 aa)
P3H1Procollagen-proline 3-dioxygenase 1. (736 aa)
PAICSPhosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase. (431 aa)
ASAP1Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein. (1106 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K. (464 aa)
CIB2Calcium and integrin-binding family member 2. (187 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
DBN1Drebrin 1. (680 aa)
NEBLNebulette. (1013 aa)
TNNT3Troponin T, fast skeletal muscle. (316 aa)
SORBS1Sorbin and SH3 domain containing 1. (1289 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (339 aa)
TNNI3Troponin I, cardiac muscle. (248 aa)
TNNT1Troponin T, slow skeletal muscle. (347 aa)
LOC102266026Beta-adducin. (432 aa)
TNNI2Troponin I2, fast skeletal type. (279 aa)
ENSBMUP00000025741annotation not available (147 aa)
RHOURho-related GTP-binding protein RhoU. (257 aa)
DCTN4Dynactin subunit 4. (467 aa)
WIPF1WAS/WASL-interacting protein family member 1. (503 aa)
PRRC2BProline rich coiled-coil 2B. (2219 aa)
CDC42EP3Cdc42 effector protein 3. (254 aa)
PAWRPRKC apoptosis WT1 regulator protein. (242 aa)
APMAPAdipocyte plasma membrane-associated protein. (217 aa)
WASWiskott-Aldrich syndrome protein. (514 aa)
MYH7BMyosin heavy chain 1/2/3/4/8/13/7B/15. (1884 aa)
RHOQRho-related GTP-binding protein RhoQ. (205 aa)
HCLS1Hematopoietic lineage cell-specific protein. (485 aa)
FHL3Four and a half LIM domains protein 3. (280 aa)
CALD1Non-muscle caldesmon. (764 aa)
TNNC2Troponin C, skeletal muscle. (170 aa)
MYO18AMyosin XVIIIA. (2049 aa)
SPATA17Spermatogenesis associated 17. (217 aa)
BICD2Protein bicaudal D-like protein 2. (836 aa)
PDCD6IPProgrammed cell death 6-interacting protein. (875 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (440 aa)
FLNBFilamin-B. (2633 aa)
SYNPO2Synaptopodin-2. (125 aa)
AMOTAngiomotin. (1079 aa)
M91_11552DUF3496 domain-containing protein. (511 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
ANKRD26ANK_REP_REGION domain-containing protein. (270 aa)
AFAP1Actin filament-associated protein 1. (786 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1339 aa)
CDC42BPBSerine/threonine-protein kinase MRCK beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1672 aa)
MYH11Myosin-11. (275 aa)
FAM107AProtein FAM107A. (225 aa)
M91_09989CCDC144C domain-containing protein. (310 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform. (192 aa)
TMOD1Tropomodulin-1. (359 aa)
WDR1WD repeat-containing protein 1. (606 aa)
GAS2Growth arrest-specific protein 2. (313 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (326 aa)
DYNLL2Dynein light chain. (128 aa)
PEAK1Tyrosine-protein kinase SgK269. (1755 aa)
POF1BProtein POF1B. (590 aa)
SNX9Sorting nexin-9. (600 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (417 aa)
MYL12AMyosin regulatory light chain 12A. (178 aa)
DEF6Differentially expressed in FDCP 6-like protein. (631 aa)
ENSBMUP00000001590annotation not available (386 aa)
ENSBMUP00000001481Heterogeneous nuclear ribonucleoprotein K-like. (90 aa)
MYL9Myosin regulatory light polypeptide 9. (172 aa)
DAAM1Disheveled-associated activator of morphogenesis 1. (1078 aa)
MYO18BMyosin-XVIIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2456 aa)
SH3PXD2ASH3 and PX domain-containing protein 2A. (1133 aa)
M91_04522Espin. (411 aa)
ENSBMUP00000000849annotation not available (98 aa)
BMFBcl-2-modifying factor. (184 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (562 aa)
M91_10244ANK_REP_REGION domain-containing protein. (310 aa)
TMOD3Tropomodulin-3. (352 aa)
H1-0Histone H1.0. (194 aa)
TRIOBPTRIO and F-actin-binding protein. (568 aa)
ENSBMUP00000012720annotation not available (110 aa)
TPM4Tropomyosin alpha-1 chain; Belongs to the tropomyosin family. (300 aa)
M91_03330Uncharacterized protein. (414 aa)
M91_03329Putative myosin-XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1430 aa)
ABLIM1Actin-binding LIM protein 1. (835 aa)
KNCNKinocilin. (124 aa)
TNNI1Troponin I, slow skeletal muscle. (187 aa)
DCTN3Dynactin subunit 3. (190 aa)
DDX58Putative ATP-dependent RNA helicase DDX58. (942 aa)
LOC102268264Keratin, type I cytoskeletal 42; Belongs to the intermediate filament family. (436 aa)
ENSBMUP00000023658Growth arrest-specific protein 7-like. (216 aa)
MYH13Myosin-13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa)
ACKR2Chemokine-binding protein 2; Belongs to the G-protein coupled receptor 1 family. (435 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
MYO15AMyosin XVA. (792 aa)
MYL3Myosin light chain 3. (232 aa)
SH3PXD2BSH3 and PX domain-containing protein 2B. (907 aa)
MOKMAPK/MAK/MRK overlapping kinase; Belongs to the protein kinase superfamily. (231 aa)
SPTBSpectrin beta, erythrocytic. (2331 aa)
MYL6BMyosin light chain 6B. (262 aa)
ACTN2Alpha-actinin-2. (894 aa)
M91_03436Endo/exonuclease/phosphatase domain-containing protein. (345 aa)
MPRIPMyosin phosphatase Rho-interacting protein. (1007 aa)
MYH3Myosin-3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1917 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2335 aa)
KLHL2Kelch-like protein 2. (555 aa)
ENSBMUP00000020973annotation not available (166 aa)
LIMCH1LIM and calponin homology domains 1. (166 aa)
ENSBMUP00000020839annotation not available (72 aa)
CCDC88AGirdin. (1869 aa)
ENSBMUP00000020678annotation not available (157 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (789 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (511 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1615 aa)
FMN1Formin-1. (1184 aa)
ARPC1AActin-related protein 2/3 complex subunit 1A-like. (279 aa)
UBR7Ubiquitin protein ligase E3 component n-recognin 7 (putative). (422 aa)
ENSBMUP00000019939Leucine-rich repeat-containing protein 16C-like. (203 aa)
FERMT3Fermitin family member 3. (665 aa)
AFAP1L1Actin filament-associated protein 1-like 1. (763 aa)
ABLIM3Actin-binding LIM protein 3. (683 aa)
DCTN6Dynactin subunit 6. (190 aa)
PDLIM4PDZ and LIM domain protein 4. (332 aa)
ABL2ABL proto-oncogene 2, non-receptor tyrosine kinase. (1177 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
CAPZBCapping protein (actin filament) muscle Z-line, beta. (301 aa)
ZYXZyxin. (505 aa)
PEAK3Uncharacterized protein. (469 aa)
RFLNBRefilin B. (131 aa)
AUHMethylglutaconyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (316 aa)
MYO1DMyosin-Id; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (949 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
Server load: low (20%) [HD]