20 items (Bos mutus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAPGEF6	Rap guanine nucleotide exchange factor 6. (1608 aa)
	RASGRF1	Ras-specific guanine nucleotide-releasing factor 1. (1257 aa)
	RGL1	Ral guanine nucleotide dissociation stimulator-like 1. (843 aa)
	SOS2	Son of sevenless-like protein 2. (1272 aa)
	RASGEF1B	Ras-GEF domain-containing family member 1B. (558 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1265 aa)
	RALGDS	Ral guanine nucleotide dissociation stimulator. (874 aa)
	RASGRF2	Ras-specific guanine nucleotide-releasing factor 2. (1239 aa)
	RASGRP4	RAS guanyl-releasing protein 4. (673 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (923 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (1007 aa)
	RASGRP1	RAS guanyl-releasing protein 1. (797 aa)
	RGL3	Ral guanine nucleotide dissociation stimulator-like 3. (727 aa)
	SOS1	Son of sevenless-like protein 1. (1333 aa)
	RGL2	Ral guanine nucleotide dissociation stimulator-like 2. (778 aa)
	RASGEF1C	Ras-GEF domain-containing family member 1C. (236 aa)
	RASGEF1A	Ras-GEF domain-containing family member 1A. (488 aa)
	RAPGEF5	Rap guanine nucleotide exchange factor 5. (731 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1676 aa)
	RASGRP3	Ras guanyl-releasing protein 3. (692 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RAPGEF2	RAPGEF6	ENSBMUP00000033402	ENSBMUP00000020987	Rap guanine nucleotide exchange factor 2.	Rap guanine nucleotide exchange factor 6.	0.901
RAPGEF3	RAPGEF4	ENSBMUP00000001796	ENSBMUP00000001578	Rap guanine nucleotide exchange factor 3.	Rap guanine nucleotide exchange factor 4.	0.950
RAPGEF4	RAPGEF3	ENSBMUP00000001578	ENSBMUP00000001796	Rap guanine nucleotide exchange factor 4.	Rap guanine nucleotide exchange factor 3.	0.950
RAPGEF6	RAPGEF2	ENSBMUP00000020987	ENSBMUP00000033402	Rap guanine nucleotide exchange factor 6.	Rap guanine nucleotide exchange factor 2.	0.901
RASGRF1	RASGRF2	ENSBMUP00000035603	ENSBMUP00000003663	Ras-specific guanine nucleotide-releasing factor 1.	Ras-specific guanine nucleotide-releasing factor 2.	0.991
RASGRF2	RASGRF1	ENSBMUP00000003663	ENSBMUP00000035603	Ras-specific guanine nucleotide-releasing factor 2.	Ras-specific guanine nucleotide-releasing factor 1.	0.991
RASGRP1	RASGRP3	ENSBMUP00000000358	ENSBMUP00000023593	RAS guanyl-releasing protein 1.	Ras guanyl-releasing protein 3.	0.521
RASGRP1	SOS1	ENSBMUP00000000358	ENSBMUP00000007852	RAS guanyl-releasing protein 1.	Son of sevenless-like protein 1.	0.918
RASGRP1	SOS2	ENSBMUP00000000358	ENSBMUP00000028605	RAS guanyl-releasing protein 1.	Son of sevenless-like protein 2.	0.915
RASGRP3	RASGRP1	ENSBMUP00000023593	ENSBMUP00000000358	Ras guanyl-releasing protein 3.	RAS guanyl-releasing protein 1.	0.521
RASGRP3	SOS1	ENSBMUP00000023593	ENSBMUP00000007852	Ras guanyl-releasing protein 3.	Son of sevenless-like protein 1.	0.915
RASGRP3	SOS2	ENSBMUP00000023593	ENSBMUP00000028605	Ras guanyl-releasing protein 3.	Son of sevenless-like protein 2.	0.915
SOS1	RASGRP1	ENSBMUP00000007852	ENSBMUP00000000358	Son of sevenless-like protein 1.	RAS guanyl-releasing protein 1.	0.918
SOS1	RASGRP3	ENSBMUP00000007852	ENSBMUP00000023593	Son of sevenless-like protein 1.	Ras guanyl-releasing protein 3.	0.915
SOS1	SOS2	ENSBMUP00000007852	ENSBMUP00000028605	Son of sevenless-like protein 1.	Son of sevenless-like protein 2.	0.940
SOS2	RASGRP1	ENSBMUP00000028605	ENSBMUP00000000358	Son of sevenless-like protein 2.	RAS guanyl-releasing protein 1.	0.915
SOS2	RASGRP3	ENSBMUP00000028605	ENSBMUP00000023593	Son of sevenless-like protein 2.	Ras guanyl-releasing protein 3.	0.915
SOS2	SOS1	ENSBMUP00000028605	ENSBMUP00000007852	Son of sevenless-like protein 2.	Son of sevenless-like protein 1.	0.940