STRINGSTRING
MET MET GUCY2F GUCY2F BRAF BRAF LMTK2 LMTK2 HCK HCK CSK CSK EPHA8 EPHA8 CSF1R CSF1R LOC102269868 LOC102269868 FGFR2 FGFR2 PDGFRA PDGFRA ITK ITK NEK7 NEK7 EPHA3 EPHA3 NTRK1 NTRK1 INSRR INSRR LOC102275569 LOC102275569 TGFBR2 TGFBR2 MAP3K7 MAP3K7 PTK2B PTK2B FYN FYN ERBB3 ERBB3 PTK6 PTK6 SRMS SRMS TIE1 TIE1 FGR FGR TESK2 TESK2 AATK AATK EPHA4 EPHA4 MATK MATK EPHB4 EPHB4 EPHB3 EPHB3 NTRK2 NTRK2 TYRO3 TYRO3 RIPK4 RIPK4 BMX BMX NEK6 NEK6 KIT KIT POMK POMK TEX14 TEX14 SCYL3 SCYL3 TNK2 TNK2 FGFR3 FGFR3 MST1R MST1R MAP3K12 MAP3K12 TEK TEK GUCY2D GUCY2D MLKL MLKL YES1 YES1 FLT1 FLT1 FLT3 FLT3 ACVR1 ACVR1 AXL AXL ACVR1C ACVR1C TESK1 TESK1 LIMK2 LIMK2 MERTK MERTK DSTYK DSTYK ZAP70 ZAP70 JAK3 JAK3 ARAF ARAF BMPR1A BMPR1A ERBB4 ERBB4 NPR1 NPR1 STYK1 STYK1 GUCY2C GUCY2C SRC SRC MAP3K20 MAP3K20 MAP3K9 MAP3K9 MAP3K11 MAP3K11 BLK BLK IGF1R IGF1R FRK FRK JAK2 JAK2 EPHA10 EPHA10 RYK RYK FER FER EPHB1 EPHB1 ABL1 ABL1 BMPR1B BMPR1B LOC102283139 LOC102283139 TNK1 TNK1 LOC102264510 LOC102264510 TXK TXK MAP3K21 MAP3K21 FGFR4 FGFR4 FES FES ACVRL1 ACVRL1 ROR1 ROR1 NRBP1 NRBP1 ROR2 ROR2 SYK SYK ROS1 ROS1 RIPK2 RIPK2 MAP3K13 MAP3K13 LIMK1 LIMK1 RAF1 RAF1 FGFR1 FGFR1 BTK BTK KSR1 KSR1 LYN LYN FLT4 FLT4 PDGFRB PDGFRB EPHA5 EPHA5 DDR2 DDR2 KSR2 KSR2 ALK ALK ILK ILK EPHA7 EPHA7 PTK2 PTK2 RET RET TYK2 TYK2 EPHA1 EPHA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
METHepatocyte growth factor receptor. (1384 aa)
GUCY2FGuanylate cyclase. (1108 aa)
BRAFSerine/threonine-protein kinase B-raf. (790 aa)
LMTK2Serine/threonine-protein kinase LMTK2. (1450 aa)
HCKTyrosine-protein kinase. (524 aa)
CSKTyrosine-protein kinase. (470 aa)
EPHA8Ephrin type-A receptor 8. (1005 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (958 aa)
LOC102269868Receptor protein-tyrosine kinase. (722 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
ITKNon-specific protein-tyrosine kinase. (424 aa)
NEK7Serine/threonine-protein kinase Nek7; Belongs to the protein kinase superfamily. (302 aa)
EPHA3Ephrin type-A receptor 3. (984 aa)
NTRK1Tyrosine-protein kinase receptor. (799 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
LOC102275569Ephrin type-A receptor 6. (367 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PTK2BProtein-tyrosine kinase 2-beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FYNTyrosine-protein kinase. (537 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1336 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SRMSTyrosine-protein kinase. (497 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1071 aa)
FGRTyrosine-protein kinase. (527 aa)
TESK2Dual specificity testis-specific protein kinase 2. (573 aa)
AATKSerine/threonine-protein kinase LMTK1. (1351 aa)
EPHA4Ephrin type-A receptor 4. (986 aa)
MATKTyrosine-protein kinase. (485 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
EPHB3Ephrin type-B receptor 3. (998 aa)
NTRK2Tyrosine-protein kinase receptor. (837 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (851 aa)
RIPK4Receptor-interacting serine/threonine-protein kinase 4. (734 aa)
BMXTyrosine-protein kinase. (655 aa)
NEK6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (333 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
POMKProtein kinase-like protein SgK196. (350 aa)
TEX14Testis-expressed protein 14. (1497 aa)
SCYL3Protein-associating with the carboxyl-terminal domain of ezrin. (733 aa)
TNK2Activated CDC42 kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1034 aa)
FGFR3Fibroblast growth factor receptor 3. (788 aa)
MST1RMacrophage-stimulating protein receptor. (1291 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
GUCY2DGuanylate cyclase. (1051 aa)
MLKLMixed lineage kinase domain-like protein. (468 aa)
YES1Tyrosine-protein kinase. (543 aa)
FLT1Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
FLT3FL cytokine receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
AXLTyrosine-protein kinase receptor UFO. (873 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
TESK1Dual specificity testis-specific protein kinase 1. (630 aa)
LIMK2LIM domain kinase 2. (658 aa)
MERTKTyrosine-protein kinase Mer. (1019 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (928 aa)
ZAP70Non-specific protein-tyrosine kinase. (617 aa)
JAK3Tyrosine-protein kinase. (1133 aa)
ARAFSerine/threonine-protein kinase A-Raf. (611 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ERBB4Receptor tyrosine-protein kinase erbB-4. (804 aa)
NPR1Guanylate cyclase. (1058 aa)
STYK1Tyrosine-protein kinase STYK1. (427 aa)
GUCY2CGuanylate cyclase. (1072 aa)
SRCTyrosine-protein kinase. (559 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase MLT. (800 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase 9. (1105 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (862 aa)
BLKTyrosine-protein kinase. (524 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
FRKTyrosine-protein kinase. (515 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
EPHA10Ephrin type-A receptor 10. (295 aa)
RYKTyrosine-protein kinase RYK. (607 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
EPHB1Ephrin type-B receptor 1. (545 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC102283139Serine/threonine-protein kinase TNNI3K. (634 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (659 aa)
LOC102264510Tyrosine-protein kinase. (475 aa)
TXKTyrosine-protein kinase. (550 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase MLK4. (930 aa)
FGFR4Fibroblast growth factor receptor. (799 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (814 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (583 aa)
ROR1Tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (874 aa)
NRBP1Nuclear receptor-binding protein. (543 aa)
ROR2Receptor protein-tyrosine kinase. (656 aa)
SYKNon-specific protein-tyrosine kinase. (629 aa)
ROS1Tyrosine-protein kinase receptor. (2345 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (539 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
LIMK1LIM domain kinase 1. (614 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
FGFR1Basic fibroblast growth factor receptor 1. (852 aa)
BTKTyrosine-protein kinase. (659 aa)
KSR1Kinase suppressor of Ras 1. (928 aa)
LYNTyrosine-protein kinase. (512 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1361 aa)
PDGFRBBeta-type platelet-derived growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1103 aa)
EPHA5Ephrin type-A receptor 5. (1031 aa)
DDR2Discoidin domain-containing receptor 2. (855 aa)
KSR2Kinase suppressor of Ras 2. (950 aa)
ALKTyrosine-protein kinase receptor. (528 aa)
ILKIntegrin-linked protein kinase. (452 aa)
EPHA7Ephrin type-A receptor 7. (998 aa)
PTK2Focal adhesion kinase 1. (1065 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
TYK2Non-specific protein-tyrosine kinase. (1187 aa)
EPHA1Ephrin type-A receptor 1. (980 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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