STRINGSTRING
AIMP1 AIMP1 MCM10 MCM10 POT1 POT1 LIG1 LIG1 EIF1AX EIF1AX TTC14 TTC14 MEIOB MEIOB POLR2H POLR2H EXOSC1 EXOSC1 LIG4 LIG4 RNGTT RNGTT CARHSP1 CARHSP1 CCAR1 CCAR1 LIN28B LIN28B POLR2G POLR2G MCM7 MCM7 DIS3 DIS3 MCM9 MCM9 PSMC3 PSMC3 MRPS17 MRPS17 RPS28 RPS28 YBX3 YBX3 LOC102266881 LOC102266881 NARS1 NARS1 PDCD11 PDCD11 MCMDC2 MCMDC2 MCM5 MCM5 SSBP1 SSBP1 EIF1AD EIF1AD LIG3 LIG3 MRPL2 MRPL2 PSMC1 PSMC1 NARS2 NARS2 M91_08968 M91_08968 MCM4 MCM4 DDIAS DDIAS PSMC2 PSMC2 RPA1 RPA1 STN1 STN1 EIF5A2 EIF5A2 IFI16 IFI16 TEN1 TEN1 M91_12762 M91_12762 YARS1 YARS1 EIF2S1 EIF2S1 M91_03358 M91_03358 DIS3L2 DIS3L2 ZCCHC17 ZCCHC17 SUPT6H SUPT6H RPS23 RPS23 M91_18057 M91_18057 M91_21397 M91_21397 YBX2 YBX2 EIF5A EIF5A PSMC5 PSMC5 RPA3 RPA3 EXOSC2 EXOSC2 SRBD1 SRBD1 DIS3L DIS3L M91_02959 M91_02959 DARS2 DARS2 DARS1 DARS1 LOC102276449 LOC102276449 M91_11308 M91_11308 RADX RADX EXOSC3 EXOSC3 PNPT1 PNPT1 MRPS12 MRPS12 PSMC4 PSMC4 MCM8 MCM8 NABP1 NABP1 LIN28A LIN28A POLR3H POLR3H CSDC2 CSDC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (336 aa)
MCM10Protein MCM10-like protein. (871 aa)
POT1Protection of telomeres protein 1. (473 aa)
LIG1DNA ligase. (883 aa)
EIF1AXEukaryotic translation initiation factor 1A, X-chromosomal; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
TTC14Tetratricopeptide repeat protein 14. (771 aa)
MEIOBUncharacterized protein. (472 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
EXOSC13'-5' exoribonuclease CSL4-like protein. (195 aa)
LIG4DNA ligase. (911 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (595 aa)
CARHSP1Calcium-regulated heat stable protein 1. (147 aa)
CCAR1Cell division cycle and apoptosis regulator protein 1. (1149 aa)
LIN28BProtein lin-28-like protein B. (255 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (187 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
DIS3Exosome complex exonuclease RRP44; Belongs to the RNR ribonuclease family. (958 aa)
MCM9DNA replication licensing factor MCM9; Belongs to the MCM family. (1139 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (440 aa)
MRPS1728S ribosomal protein S17, mitochondrial. (130 aa)
RPS2840S ribosomal protein S28. (69 aa)
YBX3DNA-binding protein A. (385 aa)
LOC10226688160S ribosomal protein L8. (276 aa)
NARS1Asparaginyl-tRNA synthetase, cytoplasmic. (548 aa)
PDCD11Protein RRP5-like protein. (1874 aa)
MCMDC2Uncharacterized protein. (681 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
SSBP1Single-stranded DNA-binding protein, mitochondrial. (148 aa)
EIF1ADPutative RNA-binding protein EIF1AD. (166 aa)
LIG3DNA ligase. (1002 aa)
MRPL239S ribosomal protein L2, mitochondrial. (306 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
NARS2Putative asparaginyl-tRNA synthetase, mitochondrial. (478 aa)
M91_08968Nuclease-sensitive element-binding protein 1. (345 aa)
MCM4DNA helicase; Belongs to the MCM family. (789 aa)
DDIASNitric oxide-inducible protein. (985 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (371 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
IFI16Interferon-activable protein 203. (521 aa)
TEN1CST complex subunit TEN1. (252 aa)
M91_12762RPA_C domain-containing protein. (251 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
M91_03358Uncharacterized protein. (120 aa)
DIS3L2DIS3-like exonuclease 2; Belongs to the RNR ribonuclease family. (882 aa)
ZCCHC17Nucleolar protein of 40 kDa. (241 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1720 aa)
RPS2340S ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
M91_18057Uncharacterized protein. (130 aa)
M91_21397Ribosomal_S17_N domain-containing protein. (74 aa)
YBX2Y-box-binding protein 2. (335 aa)
EIF5AEukaryotic translation initiation factor 5A. (183 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
EXOSC2Exosome complex exonuclease RRP4. (293 aa)
SRBD1S1 RNA-binding domain-containing protein 1. (1009 aa)
DIS3LDIS3-like exonuclease 1; Belongs to the RNR ribonuclease family. (995 aa)
M91_02959Uncharacterized protein. (69 aa)
DARS2Aspartyl-tRNA synthetase, mitochondrial. (644 aa)
DARS1Aspartyl-tRNA synthetase, cytoplasmic. (501 aa)
LOC102276449Replication protein A 32 kDa subunit. (270 aa)
M91_1130840S ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (150 aa)
RADXUncharacterized protein. (855 aa)
EXOSC3Exosome complex exonuclease RRP40. (275 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (783 aa)
MRPS1228S ribosomal protein S12, mitochondrial; Belongs to the universal ribosomal protein uS12 family. (139 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
MCM8DNA replication licensing factor MCM8; Belongs to the MCM family. (832 aa)
NABP1SOSS complex subunit B2. (206 aa)
LIN28AProtein lin-28-like protein A. (205 aa)
POLR3HDNA-directed RNA polymerase III subunit RPC8. (204 aa)
CSDC2Cold shock domain-containing protein C2. (199 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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