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| | NSUN6 | Putative methyltransferase NSUN6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (470 aa) |
| | METTL21C | Uncharacterized protein. (257 aa) |
| | PRMT9 | TPR_REGION domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (844 aa) |
| | M91_15134 | Uncharacterized protein. (240 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (370 aa) |
| | METTL1 | tRNA (guanine(46)-N(7))-methyltransferase. (277 aa) |
| | EEF1AKMT3 | Protein FAM119B. (226 aa) |
| | TRMT5 | tRNA (Guanine-N(1)-)-methyltransferase. (497 aa) |
| | METTL9 | Methyltransferase-like protein 9. (283 aa) |
| | METTL2A | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (378 aa) |
| | PCMTD2 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2. (361 aa) |
| | NSUN2 | tRNA (Cytosine-5-)-methyltransferase NSUN2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (840 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | TRMT12 | tRNA wybutosine-synthesizing protein 2-like protein. (462 aa) |
| | METTL15 | Putative S-adenosyl-L-methionine-dependent methyltransferase METT5D1. (407 aa) |
| | METTL26 | Uncharacterized protein. (204 aa) |
| | TFB1M | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (339 aa) |
| | ANTKMT | Protein FAM173A. (232 aa) |
| | BCDIN3D | Putative methyltransferase BCDIN3D. (393 aa) |
| | ASMT | Hydroxyindole O-methyltransferase. (345 aa) |
| | M91_13497 | N-acetylserotonin O-methyltransferase-like protein. (238 aa) |
| | METTL22 | Uncharacterized protein. (413 aa) |
| | TRMT1L | TRM1-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (737 aa) |
| | EEF1AKNMT | Methyltransferase-like protein 13. (699 aa) |
| | VCPKMT | Uncharacterized protein. (229 aa) |
| | COQ5 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (330 aa) |
| | METTL11B | Uncharacterized protein. (283 aa) |
| | METTL25 | Methyltranfer_dom domain-containing protein. (451 aa) |
| | METTL18 | Uncharacterized protein. (373 aa) |
| | TRMT61A | tRNA (Adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A. (300 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1696 aa) |
| | HEMK1 | HemK methyltransferase family member 1. (363 aa) |
| | LCMT2 | Leucine carboxyl methyltransferase 2. (39 aa) |
| | ECE2 | Endothelin-converting enzyme 2. (782 aa) |
| | HNMT | Histamine N-methyltransferase. (292 aa) |
| | MRM2 | Putative ribosomal RNA methyltransferase 2. (244 aa) |
| | EEF1AKMT1 | EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. (250 aa) |
| | NSUN4 | Putative methyltransferase NSUN4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (384 aa) |
| | SMS | Spermine synthase. (350 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | METTL7B | Methyltransferase-like protein 7B. (244 aa) |
| | M91_10035 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (239 aa) |
| | PRMT8 | Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa) |
| | LOC102277953 | Transmembrane O-methyltransferase. (258 aa) |
| | METTL3 | N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa) |
| | PRMT2 | Protein arginine N-methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (434 aa) |
| | NSUN7 | Putative methyltransferase NSUN7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (722 aa) |
| | RRNAD1 | Methyltranfer_dom domain-containing protein. (475 aa) |
| | COMTD1 | Catechol O-methyltransferase domain-containing protein 1. (262 aa) |
| | FBL | rRNA 2'-O-methyltransferase fibrillarin. (322 aa) |
| | NSUN3 | Putative methyltransferase NSUN3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (340 aa) |
| | TRMT1 | N(2),N(2)-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (676 aa) |
| | M91_16726 | Methyltransf_11 domain-containing protein. (205 aa) |
| | LOC102270564 | Methyltransferase-like protein 7A. (224 aa) |
| | DNMT3B | DNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa) |
| | M91_21227 | Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (363 aa) |
| | DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1533 aa) |
| | DNMT3L | DNA (Cytosine-5)-methyltransferase 3-like protein. (387 aa) |
| | ETFBKMT | Uncharacterized protein. (266 aa) |
| | PCMTD1 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1. (356 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (460 aa) |
| | TRMT61B | Putative tRNA (Adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B. (496 aa) |
| | TPMT | Thiopurine S-methyltransferase. (245 aa) |
| | PCMT1 | Protein-L-isoaspartate O-methyltransferase. (285 aa) |
| | THUMPD3 | THUMP domain-containing protein 3. (503 aa) |
| | TGS1 | Trimethylguanosine synthase. (853 aa) |
| | CARNMT1 | N2227 domain-containing protein. (330 aa) |
| | EEF1AKMT2 | Methyltransferase-like protein 10. (234 aa) |
| | DIMT1 | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (420 aa) |
| | METTL23 | Uncharacterized protein. (193 aa) |
| | METTL6 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (307 aa) |
| | TFB2M | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (394 aa) |
| | INMT | Indolethylamine N-methyltransferase. (278 aa) |
| | EEF2KMT | Protein FAM86A. (139 aa) |
| | RNMT | mRNA cap guanine-N7 methyltransferase. (477 aa) |
| | TRMT9B | Putative methyltransferase KIAA1456-like protein. (424 aa) |
| | TRDMT1 | tRNA (Cytosine-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (391 aa) |
| | NOP2 | Putative ribosomal RNA methyltransferase NOP2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (823 aa) |
| | METTL27 | Williams-Beuren syndrome chromosomal region 27 protein. (245 aa) |
| | LOC102279908 | Nicotinamide N-methyltransferase. (263 aa) |
| | BUD23 | Putative methyltransferase WBSCR22. (281 aa) |
| | NSUN5 | Putative methyltransferase NSUN5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (462 aa) |
| | ATPSCKMT | Protein FAM173B. (233 aa) |
| | LOC102287829 | Uncharacterized protein. (290 aa) |
| | DNMT3A | DNA (Cytosine-5)-methyltransferase 3A; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa) |
| | FTSJ3 | pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (833 aa) |
| | THUMPD2 | THUMP domain-containing protein 2. (501 aa) |
| | CAMKMT | Uncharacterized protein. (323 aa) |
| | CMTR2 | FtsJ methyltransferase domain-containing protein 1. (764 aa) |
| | NDUFAF7 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (441 aa) |
| | FTSJ1 | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (329 aa) |
| | TRMT2A | tRNA (Uracil-5-)-methyltransferase-like protein A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (628 aa) |
| | N6AMT1 | HemK methyltransferase family member 2. (214 aa) |
| | METTL14 | Methyltransferase-like protein 14; Belongs to the MT-A70-like family. (456 aa) |
| | PRMT1 | Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa) |
| | HENMT1 | Uncharacterized protein. (387 aa) |
| | GAMT | Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family. (236 aa) |
| | CARM1 | Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (614 aa) |
| | LOC102271688 | CheR domain-containing protein. (282 aa) |
| | PRMT6 | Protein arginine N-methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa) |
| | METTL5 | Methyltransferase-like protein 5. (209 aa) |
| | FBLL1 | rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1. (333 aa) |
| | METTL8 | Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (407 aa) |
| | PNMT | Phenylethanolamine N-methyltransferase. (367 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (695 aa) |
| | METTL4 | Methyltransferase-like protein 4; Belongs to the MT-A70-like family. (470 aa) |
| | NTMT1 | Uncharacterized protein. (223 aa) |
| | AS3MT | Arsenite methyltransferase. (374 aa) |
| | SRM | Spermidine synthase; Belongs to the spermidine/spermine synthase family. (302 aa) |
| | CIAPIN1 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (311 aa) |
| | MEPCE | 7SK snRNA methylphosphate capping enzyme. (687 aa) |
