(15 nodes) Regulation of cholesterol biosynthesis by SREBP (SREBF) network (Bos mutus)

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Known Interactions

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Predicted Interactions

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Your Input:
	RAN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
	NFYB	Nuclear transcription factor Y subunit beta. (207 aa)
	LOC102271928	Uncharacterized protein. (215 aa)
	SCAP	Sterol regulatory element-binding protein cleavage-activating protein. (1279 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (224 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1108 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1173 aa)
	NFYA	Nuclear transcription factor Y subunit alpha. (347 aa)
	NFYC	Nuclear transcription factor Y subunit gamma. (348 aa)
	MBTPS1	Membrane-bound transcription factor site-1 protease. (1052 aa)
	ADGRD1	Putative G-protein coupled receptor 133; Belongs to the G-protein coupled receptor 2 family. (902 aa)
	LOC102280145	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
	KPNB1	Importin subunit beta-1. (876 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (276 aa)
	MTF1	Metal regulatory transcription factor 1. (751 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRD1	KPNB1	ENSBMUP00000000465	ENSBMUP00000001175	Putative G-protein coupled receptor 133; Belongs to the G-protein coupled receptor 2 family.	Importin subunit beta-1.	0.872
INSIG1	SCAP	ENSBMUP00000003041	ENSBMUP00000017508	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element-binding protein cleavage-activating protein.	0.930
INSIG1	SREBF1	ENSBMUP00000003041	ENSBMUP00000022839	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 1.	0.673
INSIG1	SREBF2	ENSBMUP00000003041	ENSBMUP00000021235	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.597
INSIG2	SCAP	ENSBMUP00000019869	ENSBMUP00000017508	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element-binding protein cleavage-activating protein.	0.934
INSIG2	SREBF1	ENSBMUP00000019869	ENSBMUP00000022839	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 1.	0.580
INSIG2	SREBF2	ENSBMUP00000019869	ENSBMUP00000021235	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.560
KPNB1	ADGRD1	ENSBMUP00000001175	ENSBMUP00000000465	Importin subunit beta-1.	Putative G-protein coupled receptor 133; Belongs to the G-protein coupled receptor 2 family.	0.872
KPNB1	LOC102271928	ENSBMUP00000001175	ENSBMUP00000011964	Importin subunit beta-1.	Uncharacterized protein.	0.917
KPNB1	LOC102280145	ENSBMUP00000001175	ENSBMUP00000000623	Importin subunit beta-1.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.917
KPNB1	RAN	ENSBMUP00000001175	ENSBMUP00000000488	Importin subunit beta-1.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.917
KPNB1	SREBF1	ENSBMUP00000001175	ENSBMUP00000022839	Importin subunit beta-1.	Sterol regulatory element binding transcription factor 1.	0.903
KPNB1	SREBF2	ENSBMUP00000001175	ENSBMUP00000021235	Importin subunit beta-1.	Sterol regulatory element binding transcription factor 2.	0.944
LOC102271928	KPNB1	ENSBMUP00000011964	ENSBMUP00000001175	Uncharacterized protein.	Importin subunit beta-1.	0.917
LOC102271928	LOC102280145	ENSBMUP00000011964	ENSBMUP00000000623	Uncharacterized protein.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.900
LOC102271928	RAN	ENSBMUP00000011964	ENSBMUP00000000488	Uncharacterized protein.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.900
LOC102280145	KPNB1	ENSBMUP00000000623	ENSBMUP00000001175	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin subunit beta-1.	0.917
LOC102280145	LOC102271928	ENSBMUP00000000623	ENSBMUP00000011964	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Uncharacterized protein.	0.900
LOC102280145	RAN	ENSBMUP00000000623	ENSBMUP00000000488	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.925
MBTPS1	SCAP	ENSBMUP00000034487	ENSBMUP00000017508	Membrane-bound transcription factor site-1 protease.	Sterol regulatory element-binding protein cleavage-activating protein.	0.662