STRINGSTRING
STAT6 STAT6 NCK1 NCK1 PCSK4 PCSK4 THBS4 THBS4 ERAS ERAS RAPGEF1 RAPGEF1 CSDE1 CSDE1 FNDC3B FNDC3B HRAS HRAS SOS1 SOS1 NRAS NRAS PIK3CB PIK3CB NCK2 NCK2 FURIN FURIN GRB2 GRB2 PTPN11 PTPN11 PIK3R1 PIK3R1 CRK CRK COL4A1 COL4A1 PDGFC PDGFC PDGFD PDGFD COL9A2 COL9A2 PTPN12 PTPN12 PDGFA PDGFA ENSBMUP00000034506 ENSBMUP00000034506 PDGFRB PDGFRB THBS3 THBS3 PDGFRA PDGFRA STAT1 STAT1 RASA1 RASA1 COL9A1 COL9A1 STAT3 STAT3 STAT5A STAT5A CASS4 CASS4 STAT5B STAT5B PIK3CA PIK3CA LOC102280173 LOC102280173 COL6A5 COL6A5 COL6A6 COL6A6 CRKL CRKL COL6A2 COL6A2 COL6A1 COL6A1 KRAS KRAS SPP1 SPP1 COL5A3 COL5A3 BCAR1 BCAR1 COL9A3 COL9A3 THBS2 THBS2 COL5A2 COL5A2 COL3A1 COL3A1 M91_10940 M91_10940 PLCG1 PLCG1 EFS EFS PIK3R2 PIK3R2 THBS1 THBS1 PDGFB PDGFB SRC SRC COL5A1 COL5A1 PLAT PLAT FNDC3A FNDC3A COL2A1 COL2A1 GRB7 GRB7 NEDD9 NEDD9 PLG PLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT6Signal transducer and activator of transcription. (847 aa)
NCK1Cytoplasmic protein NCK1. (377 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (750 aa)
THBS4Thrombospondin-4. (988 aa)
ERASGTPase ERas. (234 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
CSDE1Cold shock domain containing E1. (839 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1207 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
NRASGTPase NRas. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
NCK2Cytoplasmic protein. (376 aa)
FURINFurin, paired basic amino acid cleaving enzyme. (695 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (593 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
CRKAdapter molecule crk. (304 aa)
COL4A1Collagen alpha-1(IV) chain. (1669 aa)
PDGFCPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (377 aa)
PDGFDPlatelet-derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
COL9A2Collagen type IX alpha 2 chain. (687 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12. (782 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (222 aa)
ENSBMUP00000034506annotation not available (1720 aa)
PDGFRBBeta-type platelet-derived growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1103 aa)
THBS3Thrombospondin-3. (956 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
STAT1Signal transducer and activator of transcription. (817 aa)
RASA1Ras GTPase-activating protein 1. (1048 aa)
COL9A1Collagen alpha-1(IX) chain. (922 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
CASS4Cas scaffolding protein family member 4. (785 aa)
STAT5BSignal transducer and activator of transcription 5B. (787 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
LOC102280173Fibronectin type III domain containing protein 3C1-like. (1297 aa)
COL6A5Collagen alpha-5(VI) chain. (2606 aa)
COL6A6Collagen type VI alpha 6 chain. (2184 aa)
CRKLCrk-like protein. (302 aa)
COL6A2Collagen alpha-2(VI) chain. (1027 aa)
COL6A1Collagen alpha-1(VI) chain. (1027 aa)
KRASGTPase KRas. (189 aa)
SPP1Osteopontin. (338 aa)
COL5A3Collagen type V/XI/XXIV/XXVII, alpha. (1744 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (866 aa)
COL9A3Collagen alpha-3(IX) chain. (684 aa)
THBS2Thrombospondin-2. (1100 aa)
COL5A2Collagen alpha-2(V) chain. (1499 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
M91_10940Tyrosine-protein phosphatase non-receptor type 11. (618 aa)
PLCG1Phosphoinositide phospholipase C. (1277 aa)
EFSEmbryonal Fyn-associated substrate. (572 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
THBS1Thrombospondin-1. (1204 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (251 aa)
SRCTyrosine-protein kinase. (559 aa)
COL5A1Collagen alpha-1(V) chain. (1841 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (567 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1198 aa)
COL2A1Collagen alpha-1(II) chain. (1486 aa)
GRB7Growth factor receptor bound protein 7. (649 aa)
NEDD9Enhancer of filamentation 1. (827 aa)
PLGPlasminogen; Belongs to the peptidase S1 family. (805 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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