STRINGSTRING
RAPGEF1 RAPGEF1 YWHAB YWHAB MAPK1 MAPK1 NGF NGF SHC2 SHC2 KIDINS220 KIDINS220 RALA RALA RALGDS RALGDS ERAS ERAS MAPK3 MAPK3 MAPKAPK2 MAPKAPK2 SHC4 SHC4 MAPKAPK3 MAPKAPK3 NKPD1 NKPD1 KRAS KRAS CRKL CRKL RALB RALB MAP2K2 MAP2K2 FRS2 FRS2 SHC3 SHC3 NTRK1 NTRK1 MAPK11 MAPK11 BRAF BRAF RIT1 RIT1 MAPK14 MAPK14 SHC1 SHC1 CRK CRK RAP1A RAP1A GRB2 GRB2 NRAS NRAS SOS1 SOS1 HRAS HRAS MAP2K1 MAP2K1 CSDE1 CSDE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
MAPK1Mitogen-activated protein kinase. (332 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (299 aa)
SHC2SHC adaptor protein 2. (450 aa)
KIDINS220Kinase D-interacting substrate of 220 kDa. (1710 aa)
RALARas-related protein Ral-A. (206 aa)
RALGDSRal guanine nucleotide dissociation stimulator. (874 aa)
ERASGTPase ERas. (234 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
SHC4SHC-transforming protein 4. (630 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
NKPD1NTPase KAP family P-loop domain-containing protein 1. (559 aa)
KRASGTPase KRas. (189 aa)
CRKLCrk-like protein. (302 aa)
RALBRas-related protein Ral-B. (234 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
SHC3SHC-transforming protein 3. (105 aa)
NTRK1Tyrosine-protein kinase receptor. (799 aa)
MAPK11Mitogen-activated protein kinase 11. (256 aa)
BRAFSerine/threonine-protein kinase B-raf. (790 aa)
RIT1GTP-binding protein Rit1. (218 aa)
MAPK14Mitogen-activated protein kinase. (369 aa)
SHC1SHC-transforming protein 1. (501 aa)
CRKAdapter molecule crk. (304 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
NRASGTPase NRas. (189 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
CSDE1Cold shock domain containing E1. (839 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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