19 items (Bos mutus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ERBB4	Receptor tyrosine-protein kinase erbB-4. (804 aa)
	EREG	Proepiregulin. (169 aa)
	BTC	Probetacellulin. (178 aa)
	ERBB2	Erb-b2 receptor tyrosine kinase 2. (1379 aa)
	LOC102279565	Pro-neuregulin-1, membrane-bound isoform-like. (127 aa)
	M91_21710	Uncharacterized protein. (274 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (116 aa)
	ERAS	GTPase ERas. (234 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform. (257 aa)
	CSDE1	Cold shock domain containing E1. (839 aa)
	HRAS	HRas proto-oncogene, GTPase. (182 aa)
	SOS1	Son of sevenless-like protein 1. (1333 aa)
	NRAS	GTPase NRas. (189 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	NRG2	Pro-neuregulin-2, membrane-bound isoform. (847 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	KRAS	GTPase KRas. (189 aa)
	LOC102275229	Receptor tyrosine-protein kinase erbB-4. (462 aa)
	NRG3	Pro-neuregulin-3, membrane-bound isoform. (346 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTC	ERBB2	ENSBMUP00000002753	ENSBMUP00000002936	Probetacellulin.	Erb-b2 receptor tyrosine kinase 2.	0.659
BTC	ERBB4	ENSBMUP00000002753	ENSBMUP00000036133	Probetacellulin.	Receptor tyrosine-protein kinase erbB-4.	0.973
BTC	EREG	ENSBMUP00000002753	ENSBMUP00000002626	Probetacellulin.	Proepiregulin.	0.744
BTC	GRB2	ENSBMUP00000002753	ENSBMUP00000011430	Probetacellulin.	Growth factor receptor-bound protein 2.	0.462
BTC	HBEGF	ENSBMUP00000002753	ENSBMUP00000019773	Probetacellulin.	Proheparin-binding EGF-like growth factor.	0.840
BTC	KRAS	ENSBMUP00000002753	ENSBMUP00000026628	Probetacellulin.	GTPase KRas.	0.529
BTC	LOC102275229	ENSBMUP00000002753	ENSBMUP00000028514	Probetacellulin.	Receptor tyrosine-protein kinase erbB-4.	0.747
BTC	LOC102279565	ENSBMUP00000002753	ENSBMUP00000003021	Probetacellulin.	Pro-neuregulin-1, membrane-bound isoform-like.	0.573
BTC	M91_21710	ENSBMUP00000002753	ENSBMUP00000003045	Probetacellulin.	Uncharacterized protein.	0.502
BTC	NRG1	ENSBMUP00000002753	ENSBMUP00000006900	Probetacellulin.	Pro-neuregulin-1, membrane-bound isoform.	0.502
BTC	NRG2	ENSBMUP00000002753	ENSBMUP00000019704	Probetacellulin.	Pro-neuregulin-2, membrane-bound isoform.	0.593
BTC	NRG4	ENSBMUP00000002753	ENSBMUP00000003253	Probetacellulin.	Pro-neuregulin-4, membrane-bound isoform.	0.544
CSDE1	ERBB2	ENSBMUP00000007301	ENSBMUP00000002936	Cold shock domain containing E1.	Erb-b2 receptor tyrosine kinase 2.	0.452
CSDE1	ERBB4	ENSBMUP00000007301	ENSBMUP00000036133	Cold shock domain containing E1.	Receptor tyrosine-protein kinase erbB-4.	0.452
CSDE1	GRB2	ENSBMUP00000007301	ENSBMUP00000011430	Cold shock domain containing E1.	Growth factor receptor-bound protein 2.	0.575
CSDE1	LOC102275229	ENSBMUP00000007301	ENSBMUP00000028514	Cold shock domain containing E1.	Receptor tyrosine-protein kinase erbB-4.	0.452
CSDE1	SOS1	ENSBMUP00000007301	ENSBMUP00000007852	Cold shock domain containing E1.	Son of sevenless-like protein 1.	0.647
ERAS	ERBB2	ENSBMUP00000006563	ENSBMUP00000002936	GTPase ERas.	Erb-b2 receptor tyrosine kinase 2.	0.478
ERAS	ERBB4	ENSBMUP00000006563	ENSBMUP00000036133	GTPase ERas.	Receptor tyrosine-protein kinase erbB-4.	0.452
ERAS	GRB2	ENSBMUP00000006563	ENSBMUP00000011430	GTPase ERas.	Growth factor receptor-bound protein 2.	0.575