STRINGSTRING
VAV1 VAV1 LOC102288172 LOC102288172 KXD1 KXD1 PSMC4 PSMC4 RPS27A RPS27A M91_01211 M91_01211 M91_13455 M91_13455 PSMD14 PSMD14 LOC102270924 LOC102270924 M91_13461 M91_13461 FBXW11 FBXW11 CHUK CHUK PSMD9 PSMD9 UBC UBC PLCG2 PLCG2 BCL10 BCL10 PSMD10 PSMD10 PSMB7 PSMB7 PPP3R1 PPP3R1 WDR92 WDR92 MAPK8 MAPK8 FCRL1 FCRL1 KRAS KRAS CARD11 CARD11 PSMD2 PSMD2 NFKB1 NFKB1 ENSBMUP00000025864 ENSBMUP00000025864 ENSBMUP00000024818 ENSBMUP00000024818 ENSBMUP00000024784 ENSBMUP00000024784 M91_09392 M91_09392 LOC102285474 LOC102285474 PSMB11 PSMB11 PSMB5 PSMB5 FCRL3 FCRL3 FCRL4 FCRL4 FCRL5 FCRL5 FCER1G FCER1G TAB1 TAB1 M91_01584 M91_01584 VAV2 VAV2 IKBKB IKBKB MAP3K20 MAP3K20 M91_06687 M91_06687 ENSBMUP00000001069 ENSBMUP00000001069 M91_06688 M91_06688 PRKCQ PRKCQ PSMD8 PSMD8 M91_19951 M91_19951 RELA RELA PSMD7 PSMD7 MAP3K1 MAP3K1 NFAT5 NFAT5 PSMB3 PSMB3 MS4A1 MS4A1 PSMA3 PSMA3 MS4A2 MS4A2 SPNS1 SPNS1 LAT LAT ENSBMUP00000002364 ENSBMUP00000002364 MALT1 MALT1 SKP1 SKP1 CLNK CLNK M91_01510 M91_01510 NFATC3 NFATC3 ENSBMUP00000003495 ENSBMUP00000003495 MAPK1 MAPK1 ENSBMUP00000003562 ENSBMUP00000003562 LOC102274744 LOC102274744 PSMB10 PSMB10 VAV3 VAV3 PSMD3 PSMD3 M91_12586 M91_12586 NFKBIA NFKBIA SKP1-2 SKP1-2 PSMD5 PSMD5 PSMF1 PSMF1 TAB3 TAB3 M91_14552 M91_14552 M91_14553 M91_14553 PSMA8 PSMA8 M91_10316 M91_10316 LOC102287375 LOC102287375 PIK3CA PIK3CA MAP3K7 MAP3K7 ENSBMUP00000022493 ENSBMUP00000022493 CDC34 CDC34 PSMA6 PSMA6 PSMA5 PSMA5 PSMA4 PSMA4 PSMC6 PSMC6 GRAP2 GRAP2 ENSBMUP00000005599 ENSBMUP00000005599 ENSBMUP00000005622 ENSBMUP00000005622 M91_14267 M91_14267 ENSBMUP00000005810 ENSBMUP00000005810 ENSBMUP00000005851 ENSBMUP00000005851 M91_08646 M91_08646 ENSBMUP00000005966 ENSBMUP00000005966 M91_19433 M91_19433 FCER1A FCER1A PSMB6 PSMB6 ERAS ERAS CALM2 CALM2 CALM3 CALM3 M91_10145 M91_10145 CSDE1 CSDE1 HRAS HRAS SOS1 SOS1 PSMC5 PSMC5 NRAS NRAS LOC102264510 LOC102264510 TXK TXK PIK3CB PIK3CB ENSBMUP00000008905 ENSBMUP00000008905 M91_20811 M91_20811 ENSBMUP00000009299 ENSBMUP00000009299 TRAV4 TRAV4 FOS FOS CUL1 CUL1 PSMB8 PSMB8 M91_16116 M91_16116 IKBKG IKBKG PPP3CB PPP3CB M91_11479 M91_11479 M91_02607 M91_02607 M91_02605 M91_02605 M91_02598 M91_02598 PLCG1 PLCG1 RAC3 RAC3 MAPK3 MAPK3 PSMA2 PSMA2 PSMB9 PSMB9 M91_19284 M91_19284 M91_19287 M91_19287 M91_01770 M91_01770 ENSBMUP00000011152 ENSBMUP00000011152 M91_19291 M91_19291 GRB2 GRB2 JUN JUN M91_13001 M91_13001 PSMD12 PSMD12 TRAF6 TRAF6 ENSBMUP00000012469 ENSBMUP00000012469 M91_06422 M91_06422 M91_06423 M91_06423 M91_14268 M91_14268 PIK3R1 PIK3R1 M91_07947 M91_07947 SYK SYK M91_17828 M91_17828 PSMD11 PSMD11 ENSBMUP00000013166 ENSBMUP00000013166 M91_15054 M91_15054 M91_06182 M91_06182 ENSBMUP00000013527 ENSBMUP00000013527 M91_03240 M91_03240 SPNS3 SPNS3 PSMC2 PSMC2 M91_03688 M91_03688 LAT2 LAT2 LCP2 LCP2 SHC1 SHC1 LOC102287219 LOC102287219 BTK BTK NFATC2 NFATC2 LOC102270021 LOC102270021 LYN LYN MAPK9 MAPK9 GAB2 GAB2 CALM1 CALM1 PSMC1 PSMC1 ENSBMUP00000016464 ENSBMUP00000016464 MAP2K4 MAP2K4 FOSL2 FOSL2 ENSBMUP00000017506 ENSBMUP00000017506 ENSBMUP00000017541 ENSBMUP00000017541 TAB2 TAB2 RAC1 RAC1 UBB UBB ENSBMUP00000019167 ENSBMUP00000019167 UBE2D2 UBE2D2 PDPK1 PDPK1 LOC102283604 LOC102283604 ENSBMUP00000020171 ENSBMUP00000020171 ENSBMUP00000035353 ENSBMUP00000035353 PSMB1 PSMB1 PSMD1 PSMD1 MAP2K7 MAP2K7 PIK3R2 PIK3R2 PSMA1 PSMA1 M91_01769 M91_01769 PSME2 PSME2 PSME1 PSME1 M91_16822 M91_16822 PSMC3 PSMC3 PSMB4 PSMB4 PSMD4 PSMD4 PSMA7 PSMA7 PAK1 PAK1 LOC102280361 LOC102280361 HARBI1 HARBI1 M91_02158 M91_02158 ENSBMUP00000030146 ENSBMUP00000030146 ENSBMUP00000030082 ENSBMUP00000030082 M91_19434 M91_19434 PSME4 PSME4 M91_11936 M91_11936 MAPK10 MAPK10 PSMD13 PSMD13 PSMB2 PSMB2 PAK2 PAK2 ENSBMUP00000028583 ENSBMUP00000028583 PPP3CA PPP3CA PSME3 PSME3 MS4A10 MS4A10 MS4A15 MS4A15 MS4A8 MS4A8 ITK ITK UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VAV1Proto-oncogene vav. (844 aa)
LOC102288172Tumor necrosis factor receptor superfamily member 16. (241 aa)
KXD1KxDL domain-containing protein. (176 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
RPS27AUbiquitin-small subunit ribosomal protein S27Ae. (156 aa)
M91_01211TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
M91_13455Ig lambda chain V-III region LOI. (160 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
LOC102270924Ig lambda chain V-IV region Bau. (134 aa)
M91_13461Ig lambda chain V-III region SH. (149 aa)
FBXW11F-box/WD repeat-containing protein 11. (531 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (740 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (221 aa)
UBCPolyubiquitin-C. (305 aa)
PLCG2Phosphoinositide phospholipase C. (1240 aa)
BCL10B-cell lymphoma/leukemia 10. (230 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (269 aa)
PSMB7Proteasome subunit beta. (277 aa)
PPP3R1Calcineurin subunit B type 1. (188 aa)
WDR92WD repeat-containing protein 92. (187 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
FCRL1Fc receptor-like protein 1. (419 aa)
KRASGTPase KRas. (189 aa)
CARD11Caspase recruitment domain-containing protein 11. (1131 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2. (908 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
ENSBMUP00000025864annotation not available (174 aa)
ENSBMUP00000024818annotation not available (160 aa)
ENSBMUP00000024784annotation not available (153 aa)
M91_09392Ig kappa chain C region. (265 aa)
LOC102285474Nuclear factor of activated T-cells, cytoplasmic 1-like. (454 aa)
PSMB11Proteasome subunit beta. (289 aa)
PSMB5Proteasome subunit beta. (263 aa)
FCRL3Fc receptor-like protein 3. (305 aa)
FCRL4Fc receptor-like protein 4. (486 aa)
FCRL5Fc receptor like 5. (942 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (111 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
M91_01584Uncharacterized protein. (342 aa)
VAV2Guanine nucleotide exchange factor VAV2. (839 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase MLT. (800 aa)
M91_06687Ig heavy chain V region MC101. (200 aa)
ENSBMUP00000001069annotation not available (113 aa)
M91_06688Ig-like domain-containing protein. (167 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (287 aa)
M91_19951IGv domain-containing protein. (122 aa)
RELATranscription factor p65. (549 aa)
PSMD726S proteasome regulatory subunit N8. (319 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1509 aa)
NFAT5Nuclear factor of activated T-cells 5. (1545 aa)
PSMB3Proteasome subunit beta. (205 aa)
MS4A1B-lymphocyte antigen CD20. (303 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta. (242 aa)
SPNS1Protein spinster-like protein 1. (526 aa)
LATLinker for activation of T-cells family member 1. (280 aa)
ENSBMUP00000002364annotation not available (153 aa)
MALT1Uncharacterized protein. (828 aa)
SKP1Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (161 aa)
CLNKCytokine-dependent hematopoietic cell linker. (166 aa)
M91_01510Ig-like domain-containing protein. (123 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3. (1038 aa)
ENSBMUP00000003495annotation not available (275 aa)
MAPK1Mitogen-activated protein kinase. (332 aa)
ENSBMUP00000003562Uncharacterized LOC102270178. (222 aa)
LOC102274744Fc receptor-like protein 2. (501 aa)
PSMB10Proteasome subunit beta. (273 aa)
VAV3Guanine nucleotide exchange factor VAV3. (874 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
M91_12586Ig-like domain-containing protein. (153 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
SKP1-2S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMF1Proteasome inhibitor PI31 subunit. (270 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
M91_14552Ig-like domain-containing protein. (147 aa)
M91_14553Ig-like domain-containing protein. (163 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
M91_10316Ig-like domain-containing protein. (184 aa)
LOC102287375Calmodulin. (149 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSBMUP00000022493annotation not available (109 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (234 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMA5Proteasome endopeptidase complex. (241 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC626S proteasome regulatory subunit T4. (403 aa)
GRAP2GRB2-related adapter protein 2. (316 aa)
ENSBMUP00000005599annotation not available (153 aa)
ENSBMUP00000005622annotation not available (197 aa)
M91_14267Ig-like domain-containing protein. (159 aa)
ENSBMUP00000005810annotation not available (149 aa)
ENSBMUP00000005851annotation not available (133 aa)
M91_08646Uncharacterized protein. (191 aa)
ENSBMUP00000005966annotation not available (190 aa)
M91_19433Ig heavy chain V region 1B43. (159 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha. (253 aa)
PSMB6Proteasome subunit beta. (335 aa)
ERASGTPase ERas. (234 aa)
CALM2Calmodulin 2. (194 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (159 aa)
M91_10145Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
CSDE1Cold shock domain containing E1. (839 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
NRASGTPase NRas. (189 aa)
LOC102264510Tyrosine-protein kinase. (475 aa)
TXKTyrosine-protein kinase. (550 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
ENSBMUP00000008905annotation not available (180 aa)
M91_20811Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
ENSBMUP00000009299annotation not available (160 aa)
TRAV4Ig-like domain-containing protein. (149 aa)
FOSProto-oncogene c-Fos. (380 aa)
CUL1Cullin-1; Belongs to the cullin family. (730 aa)
PSMB8Proteasome subunit beta. (276 aa)
M91_16116Ig-like domain-containing protein. (173 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
M91_11479Ig-like domain-containing protein. (156 aa)
M91_02607Ig-like domain-containing protein. (137 aa)
M91_02605Ig lambda chain V-I region BL2. (191 aa)
M91_02598IGv domain-containing protein. (117 aa)
PLCG1Phosphoinositide phospholipase C. (1277 aa)
RAC3Rac family small GTPase 3. (208 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
PSMA2Proteasome endopeptidase complex. (234 aa)
PSMB9Proteasome subunit beta. (219 aa)
M91_19284Ig kappa chain V-I region HK102. (125 aa)
M91_19287Ig-like domain-containing protein. (120 aa)
M91_01770Ig kappa chain V-II region 2S1.3. (116 aa)
ENSBMUP00000011152annotation not available (102 aa)
M91_19291Ig-like domain-containing protein. (126 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
M91_13001Ig-like domain-containing protein. (167 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa)
ENSBMUP00000012469annotation not available (147 aa)
M91_06422Ig-like domain-containing protein. (132 aa)
M91_06423Ig kappa chain V-III region SIE. (115 aa)
M91_14268Uncharacterized protein. (159 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
M91_07947Proteasome endopeptidase complex. (163 aa)
SYKNon-specific protein-tyrosine kinase. (629 aa)
M91_17828Ig-like domain-containing protein. (194 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
ENSBMUP00000013166annotation not available (161 aa)
M91_15054Ig-like domain-containing protein. (158 aa)
M91_06182Ig-like domain-containing protein. (108 aa)
ENSBMUP00000013527annotation not available (132 aa)
M91_03240Ig-like domain-containing protein. (159 aa)
SPNS3Protein spinster-like protein 3. (543 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
M91_03688Ig-like domain-containing protein. (135 aa)
LAT2Linker for activation of T-cells family member 2. (210 aa)
LCP2Lymphocyte cytosolic protein 2. (530 aa)
SHC1SHC-transforming protein 1. (501 aa)
LOC102287219Tyrosine-protein kinase ITK/TSK-like. (265 aa)
BTKTyrosine-protein kinase. (659 aa)
NFATC2Nuclear factor of activated T cells 2. (891 aa)
LOC102270021Tyrosine-protein kinase Tec-like. (170 aa)
LYNTyrosine-protein kinase. (512 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
GAB2GRB2-associated-binding protein 2. (666 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
ENSBMUP00000016464annotation not available (106 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (410 aa)
FOSL2Fos-related antigen 2. (313 aa)
ENSBMUP00000017506annotation not available (141 aa)
ENSBMUP00000017541annotation not available (311 aa)
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 2. (409 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (204 aa)
UBBPolyubiquitin-C. (191 aa)
ENSBMUP00000019167annotation not available (102 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (566 aa)
LOC102283604Ankyrin repeat and KH domain-containing protein 1. (2540 aa)
ENSBMUP00000020171annotation not available (125 aa)
ENSBMUP00000035353annotation not available (127 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1. (953 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
M91_01769Ig kappa chain V-II region RPMI 6410. (130 aa)
PSME2Proteasome activator complex subunit 2. (253 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
M91_16822Ig-like domain-containing protein. (126 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (440 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD426S proteasome regulatory subunit N10. (377 aa)
PSMA720S proteasome subunit alpha 4. (178 aa)
PAK1Non-specific serine/threonine protein kinase. (552 aa)
LOC102280361Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
HARBI1Putative nuclease HARBI1. (349 aa)
M91_02158Ig lambda-1 chain C regions. (139 aa)
ENSBMUP00000030146annotation not available (119 aa)
ENSBMUP00000030082annotation not available (147 aa)
M91_19434Ig-like domain-containing protein. (162 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
M91_11936IGv domain-containing protein. (119 aa)
MAPK10Mitogen-activated protein kinase. (370 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMB2Proteasome subunit beta. (201 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSBMUP00000028583annotation not available (70 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PSME3Proteasome activator subunit 3. (270 aa)
MS4A10Membrane-spanning 4-domains subfamily A member 10. (260 aa)
MS4A15Membrane-spanning 4-domains subfamily A member 15. (241 aa)
MS4A8Membrane-spanning 4-domains subfamily A member 8A. (246 aa)
ITKNon-specific protein-tyrosine kinase. (424 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
Server load: low (18%) [HD]