27 items (Bos mutus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS6KA4	Ribosomal protein S6 kinase alpha-4. (773 aa)
	MAPK1	Mitogen-activated protein kinase. (332 aa)
	CACNA1I	Voltage-dependent T-type calcium channel subunit alpha-1I. (2149 aa)
	NCAM2	Neural cell adhesion molecule 2. (837 aa)
	ERAS	GTPase ERas. (234 aa)
	CSDE1	Cold shock domain containing E1. (839 aa)
	HRAS	HRas proto-oncogene, GTPase. (182 aa)
	SOS1	Son of sevenless-like protein 1. (1333 aa)
	NRAS	GTPase NRas. (189 aa)
	CNTN2	Contactin-2. (1040 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1. (341 aa)
	RPS6KA5	Ribosomal protein S6 kinase alpha-5. (723 aa)
	NCAM1	Neural cell adhesion molecule 1. (878 aa)
	PTK2	Focal adhesion kinase 1. (1065 aa)
	PTPRE	Receptor-type tyrosine-protein phosphatase epsilon. (642 aa)
	SPTA1	Spectrin alpha, erythrocytic 1. (2335 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	SPTB	Spectrin beta, erythrocytic. (2331 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2363 aa)
	SPTBN4	Spectrin beta, non-erythrocytic 4. (2477 aa)
	SPTAN1	Spectrin alpha chain, brain. (2498 aa)
	SPTBN2	Spectrin beta chain; Belongs to the spectrin family. (2386 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (813 aa)
	KRAS	GTPase KRas. (189 aa)
	ENSBMUP00000025999	annotation not available (525 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTN2	NCAM1	ENSBMUP00000010003	ENSBMUP00000016005	Contactin-2.	Neural cell adhesion molecule 1.	0.619
CNTN2	NCAM2	ENSBMUP00000010003	ENSBMUP00000005669	Contactin-2.	Neural cell adhesion molecule 2.	0.595
CNTN2	PTPRA	ENSBMUP00000010003	ENSBMUP00000026929	Contactin-2.	Receptor-type tyrosine-protein phosphatase alpha.	0.461
CREB1	FYN	ENSBMUP00000013230	ENSBMUP00000022504	Cyclic AMP-responsive element-binding protein 1.	Tyrosine-protein kinase.	0.421
CREB1	MAPK3	ENSBMUP00000013230	ENSBMUP00000035411	Cyclic AMP-responsive element-binding protein 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.927
CREB1	RPS6KA4	ENSBMUP00000013230	ENSBMUP00000018862	Cyclic AMP-responsive element-binding protein 1.	Ribosomal protein S6 kinase alpha-4.	0.880
CREB1	RPS6KA5	ENSBMUP00000013230	ENSBMUP00000015396	Cyclic AMP-responsive element-binding protein 1.	Ribosomal protein S6 kinase alpha-5.	0.991
CSDE1	GRB2	ENSBMUP00000007301	ENSBMUP00000011430	Cold shock domain containing E1.	Growth factor receptor-bound protein 2.	0.575
CSDE1	SOS1	ENSBMUP00000007301	ENSBMUP00000007852	Cold shock domain containing E1.	Son of sevenless-like protein 1.	0.647
ENSBMUP00000025999	SPTA1	ENSBMUP00000025999	ENSBMUP00000021532	annotation not available	Spectrin alpha, erythrocytic 1.	0.783
ENSBMUP00000025999	SPTAN1	ENSBMUP00000025999	ENSBMUP00000028372	annotation not available	Spectrin alpha chain, brain.	0.943
ERAS	GRB2	ENSBMUP00000006563	ENSBMUP00000011430	GTPase ERas.	Growth factor receptor-bound protein 2.	0.575
ERAS	SOS1	ENSBMUP00000006563	ENSBMUP00000007852	GTPase ERas.	Son of sevenless-like protein 1.	0.677
FYN	CREB1	ENSBMUP00000022504	ENSBMUP00000013230	Tyrosine-protein kinase.	Cyclic AMP-responsive element-binding protein 1.	0.421
FYN	GRB2	ENSBMUP00000022504	ENSBMUP00000011430	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.598
FYN	HRAS	ENSBMUP00000022504	ENSBMUP00000007841	Tyrosine-protein kinase.	HRas proto-oncogene, GTPase.	0.505
FYN	KRAS	ENSBMUP00000022504	ENSBMUP00000026628	Tyrosine-protein kinase.	GTPase KRas.	0.492
FYN	NCAM1	ENSBMUP00000022504	ENSBMUP00000016005	Tyrosine-protein kinase.	Neural cell adhesion molecule 1.	0.678
FYN	NRAS	ENSBMUP00000022504	ENSBMUP00000008311	Tyrosine-protein kinase.	GTPase NRas.	0.489
FYN	PTK2	ENSBMUP00000022504	ENSBMUP00000017008	Tyrosine-protein kinase.	Focal adhesion kinase 1.	0.974