STRINGSTRING
FGF20 FGF20 KRAS KRAS KLB KLB FGF9 FGF9 FGF1 FGF1 FGF16 FGF16 FGF2 FGF2 FGF17 FGF17 FGF18 FGF18 SHC1 SHC1 GRB2 GRB2 FGFR4 FGFR4 NRAS NRAS SOS1 SOS1 HRAS HRAS FGF3 FGF3 CSDE1 CSDE1 FGF8 FGF8 ERAS ERAS FGF6 FGF6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
KRASGTPase KRas. (189 aa)
KLBBeta-klotho. (1016 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (195 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SHC1SHC-transforming protein 1. (501 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
FGFR4Fibroblast growth factor receptor. (799 aa)
NRASGTPase NRas. (189 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
CSDE1Cold shock domain containing E1. (839 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
ERASGTPase ERas. (234 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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