25 items (Bos mutus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	M91_12762	RPA_C domain-containing protein. (251 aa)
	RCBTB2	RCC1 and BTB domain-containing protein 2. (554 aa)
	RCBTB1	RCC1 and BTB domain-containing protein 1. (531 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1257 aa)
	LOC102276449	Replication protein A 32 kDa subunit. (270 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	RPA3	Replication protein A 14 kDa subunit. (121 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
	ATAD5	ATPase family AAA domain-containing protein 5. (1753 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	POLK	DNA polymerase kappa. (910 aa)
	RFC5	Replication factor C subunit 5. (339 aa)
	MAD2L2	Mitotic spindle assembly checkpoint protein MAD2B. (209 aa)
	ENSBMUP00000017506	annotation not available (141 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	UBB	Polyubiquitin-C. (191 aa)
	UBA52	Ubiquitin-60S ribosomal protein L40. (128 aa)
	KXD1	KxDL domain-containing protein. (176 aa)
	RPS27A	Ubiquitin-small subunit ribosomal protein S27Ae. (156 aa)
	REV3L	DNA polymerase zeta catalytic subunit. (3055 aa)
	RPA2	Replication protein A2. (270 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	MEIOB	Uncharacterized protein. (472 aa)
	UBC	Polyubiquitin-C. (305 aa)
	RFC1	Replication factor C subunit 1. (1147 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	ENSBMUP00000017506	ENSBMUP00000013715	ENSBMUP00000017506	ATPase family AAA domain-containing protein 5.	annotation not available	0.430
ATAD5	LOC102276449	ENSBMUP00000013715	ENSBMUP00000005252	ATPase family AAA domain-containing protein 5.	Replication protein A 32 kDa subunit.	0.465
ATAD5	M91_12762	ENSBMUP00000013715	ENSBMUP00000012105	ATPase family AAA domain-containing protein 5.	RPA_C domain-containing protein.	0.465
ATAD5	MAD2L2	ENSBMUP00000013715	ENSBMUP00000016612	ATPase family AAA domain-containing protein 5.	Mitotic spindle assembly checkpoint protein MAD2B.	0.579
ATAD5	MEIOB	ENSBMUP00000013715	ENSBMUP00000024082	ATPase family AAA domain-containing protein 5.	Uncharacterized protein.	0.708
ATAD5	PCNA	ENSBMUP00000013715	ENSBMUP00000006828	ATPase family AAA domain-containing protein 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.940
ATAD5	POLK	ENSBMUP00000013715	ENSBMUP00000015327	ATPase family AAA domain-containing protein 5.	DNA polymerase kappa.	0.592
ATAD5	REV1	ENSBMUP00000013715	ENSBMUP00000003916	ATPase family AAA domain-containing protein 5.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.607
ATAD5	REV3L	ENSBMUP00000013715	ENSBMUP00000022640	ATPase family AAA domain-containing protein 5.	DNA polymerase zeta catalytic subunit.	0.702
ATAD5	RFC1	ENSBMUP00000013715	ENSBMUP00000026200	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 1.	0.488
ATAD5	RFC2	ENSBMUP00000013715	ENSBMUP00000014293	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 2.	0.959
ATAD5	RFC3	ENSBMUP00000013715	ENSBMUP00000018321	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 3.	0.971
ATAD5	RFC4	ENSBMUP00000013715	ENSBMUP00000024060	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 4.	0.985
ATAD5	RFC5	ENSBMUP00000013715	ENSBMUP00000016457	ATPase family AAA domain-containing protein 5.	Replication factor C subunit 5.	0.963
ATAD5	RPA1	ENSBMUP00000013715	ENSBMUP00000013619	ATPase family AAA domain-containing protein 5.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.708
ATAD5	RPA2	ENSBMUP00000013715	ENSBMUP00000023143	ATPase family AAA domain-containing protein 5.	Replication protein A2.	0.465
ATAD5	RPA3	ENSBMUP00000013715	ENSBMUP00000007914	ATPase family AAA domain-containing protein 5.	Replication protein A 14 kDa subunit.	0.549
ATAD5	RPS27A	ENSBMUP00000013715	ENSBMUP00000020797	ATPase family AAA domain-containing protein 5.	Ubiquitin-small subunit ribosomal protein S27Ae.	0.430
ENSBMUP00000017506	ATAD5	ENSBMUP00000017506	ENSBMUP00000013715	annotation not available	ATPase family AAA domain-containing protein 5.	0.430
ENSBMUP00000017506	KXD1	ENSBMUP00000017506	ENSBMUP00000020600	annotation not available	KxDL domain-containing protein.	0.630