STRINGSTRING
M91_13196 M91_13196 ENSBMUP00000034660 ENSBMUP00000034660 PRDM1 PRDM1 USP7 USP7 TP53 TP53 MAPKAP1 MAPKAP1 MDM4 MDM4 RNF34 RNF34 UBC UBC CDK2 CDK2 ENSBMUP00000022382 ENSBMUP00000022382 PPP2CB PPP2CB PPP2CA PPP2CA PRR5 PRR5 ARHGAP8 ARHGAP8 ENSBMUP00000008263 ENSBMUP00000008263 CDK1 CDK1 SGK1 SGK1 DAXX DAXX M91_13835 M91_13835 CDK3 CDK3 LOC102278265 LOC102278265 MDM2 MDM2 RFFL RFFL ENSBMUP00000017506 ENSBMUP00000017506 CCNG1 CCNG1 PPP2R1B PPP2R1B CCNA1 CCNA1 ENSBMUP00000018435 ENSBMUP00000018435 UBB UBB PPP2R5C PPP2R5C RICTOR RICTOR UBA52 UBA52 KXD1 KXD1 TXNDC11 TXNDC11 RPS27A RPS27A ENSBMUP00000021670 ENSBMUP00000021670 CCNA2 CCNA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M91_13196Uncharacterized protein. (663 aa)
ENSBMUP00000034660annotation not available (127 aa)
PRDM1PR domain zinc finger protein 1. (779 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7. (1084 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (386 aa)
MAPKAP1Target of rapamycin complex 2 subunit MAPKAP1. (522 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
RNF34E3 ubiquitin-protein ligase RNF34. (391 aa)
UBCPolyubiquitin-C. (305 aa)
CDK2Cell division protein kinase 2; Belongs to the protein kinase superfamily. (346 aa)
ENSBMUP00000022382Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform-like. (273 aa)
PPP2CBSerine/threonine-protein phosphatase. (283 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PRR5Proline rich 5. (348 aa)
ARHGAP8Rho GTPase-activating protein 8. (306 aa)
ENSBMUP00000008263annotation not available (245 aa)
CDK1Cell division protein kinase 1; Belongs to the protein kinase superfamily. (297 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
DAXXDeath domain-associated protein 6. (748 aa)
M91_13835Serine-protein kinase ATM. (319 aa)
CDK3Cell division protein kinase 3; Belongs to the protein kinase superfamily. (305 aa)
LOC102278265Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (589 aa)
MDM2E3 ubiquitin-protein ligase Mdm2. (492 aa)
RFFLE3 ubiquitin-protein ligase rififylin. (369 aa)
ENSBMUP00000017506annotation not available (141 aa)
CCNG1Cyclin-G1; Belongs to the cyclin family. (295 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (667 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (421 aa)
ENSBMUP00000018435annotation not available (151 aa)
UBBPolyubiquitin-C. (191 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform. (462 aa)
RICTORRapamycin-insensitive companion of mTOR. (1737 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
KXD1KxDL domain-containing protein. (176 aa)
TXNDC11Thioredoxin domain-containing protein 11. (958 aa)
RPS27AUbiquitin-small subunit ribosomal protein S27Ae. (156 aa)
ENSBMUP00000021670annotation not available (150 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (417 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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