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KXD1 KXD1 LRRK2 LRRK2 LOC102269868 LOC102269868 HBEGF HBEGF NRG2 NRG2 RHOA RHOA UBB UBB RAC1 RAC1 DOK1 DOK1 ENSBMUP00000017506 ENSBMUP00000017506 PTPN1 PTPN1 ELMOD2 ELMOD2 ELMOD1 ELMOD1 CBL CBL CRK CRK ERAS ERAS ARHGAP35 ARHGAP35 ELMO3 ELMO3 KHDRBS3 KHDRBS3 ENSBMUP00000031206 ENSBMUP00000031206 NONO NONO HIF1A HIF1A TGFB1I1 TGFB1I1 NRG3 NRG3 CDK4 CDK4 ELMOD3 ELMOD3 RAC3 RAC3 ENSBMUP00000035935 ENSBMUP00000035935 ERBB4 ERBB4 CSDE1 CSDE1 CCND1 CCND1 ELMO1 ELMO1 NRAS NRAS CCNE1 CCNE1 ENSBMUP00000008744 ENSBMUP00000008744 ELMO2 ELMO2 NRG1 NRG1 LPXN LPXN NRG4 NRG4 M91_21710 M91_21710 ERBB2 ERBB2 BTC BTC EREG EREG KHDRBS1 KHDRBS1 CDKN1B CDKN1B SOCS3 SOCS3 RNF222 RNF222 BCAR1 BCAR1 GPNMB GPNMB SFPQ SFPQ LOC102275229 LOC102275229 PXN PXN KRAS KRAS STAP2 STAP2 ARAP1 ARAP1 PSPC1 PSPC1 LOC102283219 LOC102283219 HRAS HRAS DOCK1 DOCK1 ENSBMUP00000007420 ENSBMUP00000007420 UBC UBC CDK2 CDK2 SRMS SRMS PTK6 PTK6 ERBB3 ERBB3 RPS27A RPS27A UBA52 UBA52 STAT3 STAT3 RASA1 RASA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KXD1KxDL domain-containing protein. (176 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2527 aa)
LOC102269868Receptor protein-tyrosine kinase. (722 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform. (847 aa)
RHOATransforming protein RhoA. (193 aa)
UBBPolyubiquitin-C. (191 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (204 aa)
DOK1Docking protein 1. (483 aa)
ENSBMUP00000017506annotation not available (141 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type 1. (429 aa)
ELMOD2ELMO domain-containing protein 2. (293 aa)
ELMOD1ELMO domain-containing protein 1. (334 aa)
CBLE3 ubiquitin-protein ligase CBL. (906 aa)
CRKAdapter molecule crk. (304 aa)
ERASGTPase ERas. (234 aa)
ARHGAP35Glucocorticoid receptor DNA-binding factor 1. (1500 aa)
ELMO3Engulfment and cell motility 3. (607 aa)
KHDRBS3KH domain-containing, RNA-binding, signal transduction-associated protein 3. (319 aa)
ENSBMUP00000031206Dedicator of cytokinesis protein 1-like. (410 aa)
NONONon-POU domain-containing octamer-binding protein. (470 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (601 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform. (346 aa)
CDK4Cell division protein kinase 4; Belongs to the protein kinase superfamily. (303 aa)
ELMOD3ELMO domain-containing protein 3. (381 aa)
RAC3Rac family small GTPase 3. (208 aa)
ENSBMUP00000035935annotation not available (300 aa)
ERBB4Receptor tyrosine-protein kinase erbB-4. (804 aa)
CSDE1Cold shock domain containing E1. (839 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (67 aa)
ELMO1Engulfment and cell motility protein 1. (727 aa)
NRASGTPase NRas. (189 aa)
CCNE1G1/S-specific cyclin-E1. (411 aa)
ENSBMUP00000008744annotation not available (181 aa)
ELMO2Engulfment and cell motility protein 2. (720 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform. (257 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
M91_21710Uncharacterized protein. (274 aa)
ERBB2Erb-b2 receptor tyrosine kinase 2. (1379 aa)
BTCProbetacellulin. (178 aa)
EREGProepiregulin. (169 aa)
KHDRBS1KH domain-containing, RNA-binding, signal transduction-associated protein 1. (441 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
RNF222RING finger protein 222. (209 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (866 aa)
GPNMBTransmembrane glycoprotein NMB. (554 aa)
SFPQSplicing factor, proline-and glutamine-rich. (700 aa)
LOC102275229Receptor tyrosine-protein kinase erbB-4. (462 aa)
PXNPaxillin. (587 aa)
KRASGTPase KRas. (189 aa)
STAP2Signal-transducing adaptor protein 2. (407 aa)
ARAP1Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1. (1456 aa)
PSPC1Paraspeckle component 1. (520 aa)
LOC102283219Epidermal growth factor receptor. (500 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
DOCK1Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1199 aa)
ENSBMUP00000007420annotation not available (87 aa)
UBCPolyubiquitin-C. (305 aa)
CDK2Cell division protein kinase 2; Belongs to the protein kinase superfamily. (346 aa)
SRMSTyrosine-protein kinase. (497 aa)
PTK6Tyrosine-protein kinase. (450 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1336 aa)
RPS27AUbiquitin-small subunit ribosomal protein S27Ae. (156 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
RASA1Ras GTPase-activating protein 1. (1048 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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