STRINGSTRING
PIK3R1 PIK3R1 GNB5 GNB5 GNG12 GNG12 SPHK1 SPHK1 MMP7 MMP7 EREG EREG AREG AREG SHC1 SHC1 LOC102271265 LOC102271265 CALM1 CALM1 UHMK1 UHMK1 STRN3 STRN3 PTK2 PTK2 GNG7 GNG7 CSDE1 CSDE1 M91_10145 M91_10145 MMP9 MMP9 CALM3 CALM3 GNG8 GNG8 ESR2 ESR2 CALM2 CALM2 STRN4 STRN4 LOC102269855 LOC102269855 MAPK1 MAPK1 ENSBMUP00000004167 ENSBMUP00000004167 GNAI3 GNAI3 GNB2 GNB2 ENSBMUP00000001289 ENSBMUP00000001289 XPO1 XPO1 ENSBMUP00000035353 ENSBMUP00000035353 ELK1 ELK1 PIK3R2 PIK3R2 MMP3 MMP3 ENSBMUP00000032610 ENSBMUP00000032610 GNG5 GNG5 GNB1 GNB1 GNG13 GNG13 ZDHHC21 ZDHHC21 PRKCZ PRKCZ GNG3 GNG3 LOC102280361 LOC102280361 ESR1 ESR1 GNAI2 GNAI2 KRAS KRAS TGFA TGFA FOXO3 FOXO3 PIK3R3 PIK3R3 LOC102283219 LOC102283219 CAV2 CAV2 CAV1 CAV1 STRN STRN ZDHHC7 ZDHHC7 WDR64 WDR64 PDPK1 PDPK1 HBEGF HBEGF LOC102279723 LOC102279723 LOC102269868 LOC102269868 LOC102287375 LOC102287375 PIK3CA PIK3CA GNAI1 GNAI1 GNAT3 GNAT3 SRC SRC GNGT2 GNGT2 GNB4 GNB4 HRAS HRAS NRAS NRAS M91_02967 M91_02967 M91_20811 M91_20811 HSPB1 HSPB1 GNG4 GNG4 CDKN1B CDKN1B GNB3 GNB3 PRMT8 PRMT8 HSP90AA1 HSP90AA1 S1PR3 S1PR3 EPGN EPGN GNGT1 GNGT1 GNG11 GNG11 IGF1R IGF1R PRMT1 PRMT1 GNG2 GNG2 ERAS ERAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (353 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
SPHK1Sphingosine kinase 1. (475 aa)
MMP7Matrilysin. (276 aa)
EREGProepiregulin. (169 aa)
AREGAmphiregulin. (269 aa)
SHC1SHC-transforming protein 1. (501 aa)
LOC102271265Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
UHMK1Serine/threonine-protein kinase Kist. (422 aa)
STRN3Striatin-3. (797 aa)
PTK2Focal adhesion kinase 1. (1065 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CSDE1Cold shock domain containing E1. (839 aa)
M91_10145Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
MMP9Matrix metalloproteinase-9. (712 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (159 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
ESR2Estrogen receptor beta. (527 aa)
CALM2Calmodulin 2. (194 aa)
STRN4Striatin-4. (634 aa)
LOC102269855Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MAPK1Mitogen-activated protein kinase. (332 aa)
ENSBMUP00000004167annotation not available (581 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (296 aa)
ENSBMUP00000001289annotation not available (100 aa)
XPO1Exportin-1. (1071 aa)
ENSBMUP00000035353annotation not available (127 aa)
ELK1ETS domain-containing protein Elk-1. (440 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
MMP3Stromelysin-1. (500 aa)
ENSBMUP00000032610annotation not available (66 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
PRKCZProtein kinase C zeta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (592 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC102280361Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
ESR1Estrogen receptor. (310 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
KRASGTPase KRas. (189 aa)
TGFATransforming growth factor, alpha. (160 aa)
FOXO3Forkhead box protein O3. (453 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
LOC102283219Epidermal growth factor receptor. (500 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
STRNStriatin. (706 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
WDR64WD repeat-containing protein 64. (1046 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (566 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
LOC102279723Heat shock protein 90 alpha family class A member 1. (119 aa)
LOC102269868Receptor protein-tyrosine kinase. (722 aa)
LOC102287375Calmodulin. (149 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
GNAI1Guanine nucleotide-binding protein G(i) subunit alpha. (354 aa)
GNAT3Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
SRCTyrosine-protein kinase. (559 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (80 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
NRASGTPase NRas. (189 aa)
M91_02967Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
M91_20811Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (356 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (664 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
EPGNEpigen. (153 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11. (73 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
PRMT1Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
ERASGTPase ERas. (234 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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