80 items (Bos mutus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	SESN3	Sestrin-3. (492 aa)
	ATP6V1C1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
	CASTOR1	GATS-like protein 3. (369 aa)
	FNIP2	Folliculin-interacting protein 2. (1110 aa)
	C12orf66	Chromosome unknown open reading frame, human C12orf66. (443 aa)
	NPRL3	Nitrogen permease regulator 3-like protein. (569 aa)
	BMT2	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa)
	WDR24	WD repeat-containing protein 24. (790 aa)
	LAMTOR4	Uncharacterized protein. (128 aa)
	DEPDC5	DEP domain-containing protein 5. (1598 aa)
	SLC38A9	Solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9. (560 aa)
	RHEBL1	GTPase RhebL1. (183 aa)
	ATP6V1F	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	WDR59	WD repeat-containing protein 59. (973 aa)
	DMRTB1	Doublesex-and mab-3-related transcription factor B1. (185 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	M91_08538	Uncharacterized protein. (91 aa)
	METTL25	Methyltranfer_dom domain-containing protein. (451 aa)
	RRAGD	Ras-related GTP-binding protein D. (397 aa)
	NPRL2	Nitrogen permease regulator 2-like protein. (380 aa)
	ENSBMUP00000026546	annotation not available (93 aa)
	ENSBMUP00000025799	annotation not available (100 aa)
	ATP6V1C2	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (437 aa)
	ITFG2	Integrin-alpha FG-GAP repeat-containing protein 2. (444 aa)
	RPTOR	Regulatory-associated protein of mTOR. (1335 aa)
	LAMTOR1	Uncharacterized protein. (161 aa)
	SESN2	Sestrin-2. (471 aa)
	ATP6V0E1	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	MACC1	Metastasis-associated in colon cancer protein 1. (841 aa)
	SZT2	Protein SZT2. (3428 aa)
	SESN1	Sestrin-1. (552 aa)
	FLCN	Folliculin. (579 aa)
	ATP6V1A	V-type proton ATPase catalytic subunit A. (618 aa)
	ATP6V1G3	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	DMRTA2	Doublesex-and mab-3-related transcription factor A2. (538 aa)
	MLST8	Target of rapamycin complex subunit LST8. (326 aa)
	ATP6V1G1	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
	TXNDC11	Thioredoxin domain-containing protein 11. (958 aa)
	FNIP1	Folliculin-interacting protein 1. (1163 aa)
	RRAGA	Ras-related GTP-binding protein A. (313 aa)
	LAMTOR2	Mitogen-activated protein-binding protein-interacting protein. (125 aa)
	ATP6V1G2	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (136 aa)
	ATP6V1H	V-type H+-transporting ATPase subunit H. (483 aa)
	CASTOR2	GATS-like protein 2. (378 aa)
	DMRTA1	Doublesex-and mab-3-related transcription factor A1. (496 aa)
	M91_00880	Uncharacterized protein. (74 aa)
	ATP6V0D2	V-type proton ATPase subunit d 2. (351 aa)
	MTOR	Serine/threonine-protein kinase mTOR. (2546 aa)
	CRYBB3	Beta-crystallin B3; Belongs to the beta/gamma-crystallin family. (211 aa)
	KIAA1671	Tankyrase_bdg_C domain-containing protein. (1800 aa)
	SEH1L	Nucleoporin SEH1; Belongs to the WD repeat SEC13 family. (356 aa)
	ATP6V0E2	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
	CNST	Consortin. (721 aa)
	LOC102266555	DM domain-containing protein. (228 aa)
	ATP6V1D	V-type proton ATPase subunit D. (247 aa)
	LIM2	Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
	LAMTOR3	Mitogen-activated protein kinase scaffold protein 1. (124 aa)
	ATP6V1E1	V-type proton ATPase subunit E 1. (226 aa)
	ENSBMUP00000011052	annotation not available (81 aa)
	RRAGB	Ras-related GTP-binding protein B-like. (371 aa)
	DMRT3	Doublesex-and mab-3-related transcription factor 3. (441 aa)
	DMRT2	Doublesex-and mab-3-related transcription factor 2. (556 aa)
	DMRTC2	Doublesex-and mab-3-related transcription factor C2. (369 aa)
	M91_02843	GTP-binding protein Rheb. (79 aa)
	ENSBMUP00000009162	annotation not available (89 aa)
	SEC13	Protein SEC13-like protein; Belongs to the WD repeat SEC13 family. (325 aa)
	MIOS	WD repeat-containing protein mio. (875 aa)
	PPP1R3A	Protein phosphatase 1 regulatory subunit 3A. (1149 aa)
	M91_09858	Uncharacterized protein. (91 aa)
	ATP6V1E2	V-type proton ATPase subunit E 2. (226 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (819 aa)
	RRAGC	Ras-related GTP-binding protein C. (389 aa)
	KPTN	Kaptin. (500 aa)
	ATP6V0D1	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	ATP6V0B	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
	LAMTOR5	Hepatitis B virus X-interacting protein-like protein. (91 aa)
	M91_06276	Uncharacterized protein. (82 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
	SH3BP4	SH3 domain-binding protein 4. (963 aa)
	ATP6V1B1	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)

Your Current Organism:

Bos mutus

NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0B	ATP6V0C	ENSBMUP00000003951	ENSBMUP00000029624	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
ATP6V0B	ATP6V0D1	ENSBMUP00000003951	ENSBMUP00000004694	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
ATP6V0B	ATP6V0D2	ENSBMUP00000003951	ENSBMUP00000014195	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit d 2.	0.996
ATP6V0B	ATP6V0E1	ENSBMUP00000003951	ENSBMUP00000023262	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.981
ATP6V0B	ATP6V0E2	ENSBMUP00000003951	ENSBMUP00000013625	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.987
ATP6V0B	ATP6V1A	ENSBMUP00000003951	ENSBMUP00000020905	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase catalytic subunit A.	0.999
ATP6V0B	ATP6V1B1	ENSBMUP00000003951	ENSBMUP00000001520	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.988
ATP6V0B	ATP6V1B2	ENSBMUP00000003951	ENSBMUP00000003073	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.990
ATP6V0B	ATP6V1C1	ENSBMUP00000003951	ENSBMUP00000035009	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
ATP6V0B	ATP6V1C2	ENSBMUP00000003951	ENSBMUP00000024342	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.945
ATP6V0B	ATP6V1D	ENSBMUP00000003951	ENSBMUP00000011674	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit D.	0.999
ATP6V0B	ATP6V1E1	ENSBMUP00000003951	ENSBMUP00000011268	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit E 1.	0.999
ATP6V0B	ATP6V1E2	ENSBMUP00000003951	ENSBMUP00000006387	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit E 2.	0.984
ATP6V0B	ATP6V1F	ENSBMUP00000003951	ENSBMUP00000030985	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
ATP6V0B	ATP6V1G1	ENSBMUP00000003951	ENSBMUP00000020670	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.982
ATP6V0B	ATP6V1G2	ENSBMUP00000003951	ENSBMUP00000017984	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.975
ATP6V0B	ATP6V1G3	ENSBMUP00000003951	ENSBMUP00000020863	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.932
ATP6V0B	ATP6V1H	ENSBMUP00000003951	ENSBMUP00000017589	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	V-type H+-transporting ATPase subunit H.	0.999
ATP6V0B	C12orf66	ENSBMUP00000003951	ENSBMUP00000033199	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	Chromosome unknown open reading frame, human C12orf66.	0.536
ATP6V0B	CNST	ENSBMUP00000003951	ENSBMUP00000013500	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family.	Consortin.	0.964