STRINGSTRING
RRAS2 RRAS2 ULK1 ULK1 ATF4 ATF4 SRC SRC CALCOCO2 CALCOCO2 RELA RELA CSNK2A2 CSNK2A2 LOC102284805 LOC102284805 RRAS RRAS TFE3 TFE3 FUNDC1 FUNDC1 TBC1D17 TBC1D17 HRAS HRAS FIS1 FIS1 NRAS NRAS MRAS MRAS GABARAP GABARAP GABARAPL1 GABARAPL1 LOC102270304 LOC102270304 MITF MITF MAPK9 MAPK9 LOC102271380 LOC102271380 MFN2 MFN2 UBB UBB CSNK2B CSNK2B RAB7A RAB7A SQSTM1 SQSTM1 BECN2 BECN2 BCL2L1 BCL2L1 BECN1 BECN1 UBA52 UBA52 RPS27A RPS27A CSNK2A1 CSNK2A1 BNIP3L BNIP3L OPTN OPTN MFN1 MFN1 RAB7B RAB7B UBC UBC FOXO3 FOXO3 TBC1D15 TBC1D15 TAX1BP1 TAX1BP1 KRAS KRAS NBR1 NBR1 MAPK8 MAPK8 USP30 USP30 TP53 TP53 TOMM7 TOMM7 MAPK10 MAPK10 PGAM5 PGAM5 SP1 SP1 PINK1 PINK1 USP8 USP8 ATG5 ATG5 AMBRA1 AMBRA1 TFEB TFEB TBK1 TBK1 E2F1 E2F1 USP15 USP15 HIF1A HIF1A ATG9A ATG9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RRAS2Ras-related protein R-Ras2. (173 aa)
ULK1Serine/threonine-protein kinase ULK1. (973 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (348 aa)
SRCTyrosine-protein kinase. (559 aa)
CALCOCO2Calcium-binding and coiled-coil domain-containing protein 2. (475 aa)
RELATranscription factor p65. (549 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
LOC102284805RBR-type E3 ubiquitin transferase. (176 aa)
RRASRas-related protein R-Ras. (218 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (598 aa)
FUNDC1FUN14 domain-containing protein 1. (155 aa)
TBC1D17TBC1 domain family member 17. (649 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (181 aa)
NRASGTPase NRas. (189 aa)
MRASRas-related protein M-Ras. (208 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
LOC102270304E3 ubiquitin-protein ligase parkin. (279 aa)
MITFMicrophthalmia-associated transcription factor. (520 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC102271380Uncharacterized protein. (174 aa)
MFN2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
UBBPolyubiquitin-C. (191 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
RAB7ARas-related protein Rab-7a. (247 aa)
SQSTM1Sequestosome-1. (356 aa)
BECN2Beclin-1-like protein 1. (439 aa)
BCL2L1Bcl-2-like protein 1. (233 aa)
BECN1Beclin-1. (448 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
RPS27AUbiquitin-small subunit ribosomal protein S27Ae. (156 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
BNIP3LBCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein. (219 aa)
OPTNOptineurin. (573 aa)
MFN1Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (742 aa)
RAB7BRas-related protein Rab-7b. (197 aa)
UBCPolyubiquitin-C. (305 aa)
FOXO3Forkhead box protein O3. (453 aa)
TBC1D15TBC1 domain family member 15. (691 aa)
TAX1BP1Tax1-binding protein 1-like protein. (817 aa)
KRASGTPase KRas. (189 aa)
NBR1Next to BRCA1 1 protein. (917 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
USP30Ubiquitin carboxyl-terminal hydrolase 30. (517 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (386 aa)
TOMM7Mitochondrial import receptor subunit TOM7-like protein. (55 aa)
MAPK10Mitogen-activated protein kinase. (370 aa)
PGAM5Serine/threonine-protein phosphatase PGAM5, mitochondrial. (140 aa)
SP1Transcription factor Sp1. (779 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the protein kinase superfamily. (468 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8. (1083 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (350 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1. (1297 aa)
TFEBTranscription factor EB. (478 aa)
TBK1Serine/threonine-protein kinase TBK1. (875 aa)
E2F1E2F transcription factor 1. (360 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (927 aa)
HIF1AHypoxia-inducible factor 1-alpha. (823 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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