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M91_06687 M91_06687 VAMP3 VAMP3 ATP6V1B1 ATP6V1B1 LOC102280754 LOC102280754 CTSV CTSV PIKFYVE PIKFYVE DYNC1I2 DYNC1I2 LOC102278231 LOC102278231 ENSBMUP00000003020 ENSBMUP00000003020 ATP6V1B2 ATP6V1B2 LOC102269978 LOC102269978 ITGB2 ITGB2 LOC102270256 LOC102270256 LOC102271117 LOC102271117 STX18 STX18 ATP6V0B ATP6V0B LOC102271676 LOC102271676 ATP6V0D1 ATP6V0D1 ATP6V0A4-2 ATP6V0A4-2 ATP6V1E2 ATP6V1E2 DYNC1LI2 DYNC1LI2 M6PR M6PR SEC61B SEC61B TUBAL3 TUBAL3 M91_10368 M91_10368 LOC102272326 LOC102272326 DYNC1I1 DYNC1I1 LOC102277803 LOC102277803 TUBB TUBB LOC102282432 LOC102282432 LOC102282710 LOC102282710 HLA-DOB HLA-DOB TAP2 TAP2 TAP1 TAP1 LOC102269342 LOC102269342 HLA-DMA HLA-DMA HLA-DOA HLA-DOA DYNC1LI1 DYNC1LI1 ATP6V1E1 ATP6V1E1 MRC1 MRC1 TUBA8 TUBA8 ATP6V1D ATP6V1D TLR2 TLR2 RAB5A RAB5A ENSBMUP00000011877 ENSBMUP00000011877 TLR4 TLR4 LOC102273069 LOC102273069 LOC102273538 LOC102273538 FCAR FCAR C1R C1R ENSBMUP00000013034 ENSBMUP00000013034 LOC102281195 LOC102281195 SCARB1 SCARB1 ATP6V0E2 ATP6V0E2 CYBB CYBB ITGB5 ITGB5 ATP6V0D2 ATP6V0D2 TUBB6 TUBB6 NCF1 NCF1 ENSBMUP00000015177 ENSBMUP00000015177 SEC61G SEC61G SEC22B SEC22B NOS1 NOS1 DYNC2H1 DYNC2H1 THBS3 THBS3 LAMP1 LAMP1 ATP6V0A2 ATP6V0A2 ATP6V1H ATP6V1H CYBA CYBA LOC102286220 LOC102286220 ATP6V1G2 ATP6V1G2 SEC61A2 SEC61A2 RAB7A RAB7A CANX CANX CALR CALR DYNC1H1 DYNC1H1 COMP COMP CD14 CD14 ATP6V1G1 ATP6V1G1 ITGB1 ITGB1 ATP6V1G3 ATP6V1G3 ATP6V1A ATP6V1A ATP6V0A1 ATP6V0A1 RAB5C RAB5C M91_20047 M91_20047 PLA2R1 PLA2R1 MARCO MARCO STX12 STX12 RAB5B RAB5B ATP6V0E1 ATP6V0E1 LOC102266138 LOC102266138 RAB7B RAB7B CTSL CTSL ATP6V1C2 ATP6V1C2 LOC102288356 LOC102288356 LOC102285693 LOC102285693 LOC102285978 LOC102285978 TLR6 TLR6 TUBB1 TUBB1 ITGA2 ITGA2 LOC102285043 LOC102285043 MPO MPO ITGA5 ITGA5 LOC102277122 LOC102277122 M91_05631 M91_05631 ACTB ACTB CLEC7A CLEC7A TFRC TFRC COLEC11 COLEC11 OLR1 OLR1 NCF2 NCF2 HLA-DRA HLA-DRA ATP6V0C ATP6V0C COLEC12 COLEC12 THBS2 THBS2 PIK3C3 PIK3C3 LAMP2 LAMP2 ITGAV ITGAV STX7 STX7 ATP6V1F ATP6V1F TUBA1A TUBA1A ENSBMUP00000031204 ENSBMUP00000031204 CTSS CTSS ENSBMUP00000032702 ENSBMUP00000032702 MSR1 MSR1 NCF4 NCF4 MRC2 MRC2 ITGB3 ITGB3 ITGAM ITGAM C3 C3 SEC61A1 SEC61A1 CD209 CD209 ATP6V1C1 ATP6V1C1 TUBA4A TUBA4A LOC102281213 LOC102281213 CORO1A CORO1A HGS HGS ACTG1 ACTG1 MBL2 MBL2 M91_12975 M91_12975 ATP6AP1 ATP6AP1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
M91_06687Ig heavy chain V region MC101. (200 aa)
VAMP3Vesicle associated membrane protein 3. (72 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
LOC102280754High affinity immunoglobulin gamma Fc receptor I. (349 aa)
CTSVCathepsin L1; Belongs to the peptidase C1 family. (334 aa)
PIKFYVE1-phosphatidylinositol-3-phosphate 5-kinase. (2110 aa)
DYNC1I2Cytoplasmic dynein 1 intermediate chain 2. (638 aa)
LOC102278231BOLA class I histocompatibility antigen, alpha chain BL3-7-like. (240 aa)
ENSBMUP00000003020HLA class II histocompatibility antigen, DQ beta 2 chain-like. (149 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
LOC102269978SLA class II histocompatibility antigen, DQ haplotype D alpha chain; Belongs to the MHC class II family. (255 aa)
ITGB2Integrin subunit beta 2. (860 aa)
LOC102270256Ig-like domain-containing protein. (272 aa)
LOC102271117HLA class II histocompatibility antigen, DRB1-4 beta chain-like. (242 aa)
STX18Syntaxin-18. (369 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
LOC102271676DLA class II histocompatibility antigen, DR-1 beta chain. (250 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
ATP6V0A4-2V-type H+-transporting ATPase subunit a. (135 aa)
ATP6V1E2V-type proton ATPase subunit E 2. (226 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
M6PRCation-dependent mannose-6-phosphate receptor. (279 aa)
SEC61BProtein transport protein Sec61 subunit beta. (96 aa)
TUBAL3Tubulin alpha like 3. (446 aa)
M91_10368Ig-like domain-containing protein; Belongs to the MHC class I family. (377 aa)
LOC102272326Ig-like domain-containing protein; Belongs to the MHC class I family. (353 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (585 aa)
LOC102277803BoLa class II histocompatibility antigen, DQB*0101 beta chain. (254 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
LOC102282432SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like. (286 aa)
LOC102282710HLA class II histocompatibility antigen, DQ beta 1 chain. (259 aa)
HLA-DOBHLA class II histocompatibility antigen, DO beta chain. (255 aa)
TAP2Antigen peptide transporter 2. (702 aa)
TAP1Antigen peptide transporter 1. (810 aa)
LOC102269342HLA class II histocompatibility antigen, DM beta chain. (262 aa)
HLA-DMAHLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (367 aa)
HLA-DOAHLA class II histocompatibility antigen, DO alpha chain; Belongs to the MHC class II family. (250 aa)
DYNC1LI1Dynein cytoplasmic 1 light intermediate chain 1. (475 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (226 aa)
MRC1Mannose receptor C-type 1. (1455 aa)
TUBA8Tubulin alpha 8. (447 aa)
ATP6V1DV-type proton ATPase subunit D. (247 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (800 aa)
RAB5ARas-related protein Rab-5A. (215 aa)
ENSBMUP00000011877Complement component 1, r subcomponent. (334 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (801 aa)
LOC102273069Uncharacterized protein. (312 aa)
LOC102273538Low affinity immunoglobulin gamma Fc region receptor III. (250 aa)
FCARFc fragment of IgA receptor. (326 aa)
C1RComplement component 1, r subcomponent. (719 aa)
ENSBMUP00000013034Tubulin beta-2B chain. (118 aa)
LOC102281195Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (432 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (513 aa)
ATP6V0E2V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
CYBBCytochrome b-245 heavy chain. (570 aa)
ITGB5Integrin beta. (786 aa)
ATP6V0D2V-type proton ATPase subunit d 2. (351 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (427 aa)
NCF1Neutrophil cytosol factor 1. (392 aa)
ENSBMUP00000015177Uncharacterized LOC102277577. (378 aa)
SEC61GProtein transport protein Sec61 subunit gamma. (68 aa)
SEC22BVesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (215 aa)
NOS1Nitric oxide synthase, brain. (1468 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1. (4314 aa)
THBS3Thrombospondin-3. (956 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (427 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
ATP6V1HV-type H+-transporting ATPase subunit H. (483 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (191 aa)
LOC102286220BOLA class I histocompatibility antigen, alpha chain BL3-6; Belongs to the MHC class I family. (480 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (136 aa)
SEC61A2Protein transport protein Sec61 subunit alpha isoform 2. (470 aa)
RAB7ARas-related protein Rab-7a. (247 aa)
CANXCalnexin. (593 aa)
CALRCalreticulin. (417 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4641 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
CD14Monocyte differentiation antigen CD14. (383 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (814 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (618 aa)
ATP6V0A1V-type H+-transporting ATPase subunit a. (838 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
M91_20047Ig-like domain-containing protein. (272 aa)
PLA2R1Secretory phospholipase A2 receptor. (1462 aa)
MARCOMacrophage receptor with collagenous structure. (390 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (274 aa)
RAB5BRas-related protein Rab-5B. (215 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
LOC102266138Uncharacterized protein; Belongs to the CD36 family. (472 aa)
RAB7BRas-related protein Rab-7b. (197 aa)
CTSLCathepsin L1; Belongs to the peptidase C1 family. (330 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (437 aa)
LOC102288356Ig-like domain-containing protein; Belongs to the MHC class I family. (337 aa)
LOC102285693Mannose-binding protein A. (248 aa)
LOC102285978Pulmonary surfactant-associated protein A. (309 aa)
TLR6Toll like receptor 6. (793 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1189 aa)
LOC102285043Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (444 aa)
MPOMyeloperoxidase. (712 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1051 aa)
LOC102277122Collectin-43. (360 aa)
M91_05631Collectin-46. (214 aa)
ACTBActin, cytoplasmic 1. (375 aa)
CLEC7AC-type lectin domain family 7 member A. (247 aa)
TFRCTransferrin receptor protein 1. (769 aa)
COLEC11Collectin-11. (267 aa)
OLR1Oxidized low-density lipoprotein receptor 1. (273 aa)
NCF2Neutrophil cytosol factor 2. (527 aa)
HLA-DRAMamu class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (319 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
COLEC12Collectin-12. (676 aa)
THBS2Thrombospondin-2. (1100 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
LAMP2Lysosome-associated membrane glycoprotein 2. (452 aa)
ITGAVIntegrin subunit alpha V. (986 aa)
STX7Syntaxin-7; Belongs to the syntaxin family. (304 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (451 aa)
ENSBMUP00000031204Tubulin alpha-1C chain. (247 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)
ENSBMUP00000032702Complement component 1, r subcomponent. (372 aa)
MSR1Macrophage scavenger receptor types I and II. (454 aa)
NCF4Neutrophil cytosol factor 4. (343 aa)
MRC2C-type mannose receptor 2. (1522 aa)
ITGB3Integrin beta. (788 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
C3Complement component 3. (1740 aa)
SEC61A1Protein transport protein Sec61 subunit alpha isoform 1. (481 aa)
CD209CD209 antigen. (259 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (448 aa)
LOC102281213Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (452 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (447 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (710 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
MBL2Mannose-binding protein C. (249 aa)
M91_12975Ig-like domain-containing protein. (341 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (460 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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