STRINGSTRING
GSK3B GSK3B SKIL SKIL HOXB1 HOXB1 PCGF6 PCGF6 ZFHX3 ZFHX3 PCGF2 PCGF2 WNT3 WNT3 OTX1 OTX1 WNT11 WNT11 WNT2B WNT2B POU5F1 POU5F1 JAK1 JAK1 HOXA1 HOXA1 APC APC WNT8B WNT8B APC2 APC2 ID2 ID2 INHBA INHBA IGF1R IGF1R JAK2 JAK2 ISL1 ISL1 MAP2K1 MAP2K1 BMPR1B BMPR1B SMAD3 SMAD3 HRAS HRAS SMAD1 SMAD1 NRAS NRAS DLX5 DLX5 PIK3CB PIK3CB LOC102279088 LOC102279088 FGFR4 FGFR4 SMAD2 SMAD2 PAX6 PAX6 FZD9 FZD9 MYC MYC ACVR2A ACVR2A GRB2 GRB2 NANOG-2 NANOG-2 PIK3R1 PIK3R1 IGF1 IGF1 FZD5 FZD5 FZD3 FZD3 RAF1 RAF1 FGFR1 FGFR1 MYF5 MYF5 FZD1 FZD1 PCGF1 PCGF1 MAPK13 MAPK13 HESX1 HESX1 WNT3A WNT3A MAPK14 MAPK14 SMAD9 SMAD9 ID3 ID3 WNT2 WNT2 FGF2 FGF2 BMP4 BMP4 ID1 ID1 FGFR2 FGFR2 LOC102274414 LOC102274414 MAPK12 MAPK12 MAPK11 MAPK11 AKT2 AKT2 STAT3 STAT3 PIK3CA PIK3CA NODAL NODAL CTNNB1 CTNNB1 WNT7A WNT7A LIFR LIFR ACVR2B ACVR2B FZD7 FZD7 BMPR2 BMPR2 MAP2K2 MAP2K2 PIK3R3 PIK3R3 RIF1 RIF1 FZD4 FZD4 LHX5 LHX5 KRAS KRAS FZD2 FZD2 ESX1 ESX1 MEIS1 MEIS1 ENSBMUP00000030233 ENSBMUP00000030233 ENSBMUP00000030236 ENSBMUP00000030236 WNT1 WNT1 ACVR1 ACVR1 ACVR1C ACVR1C IL6ST IL6ST FZD10 FZD10 SMAD4 SMAD4 PCGF5 PCGF5 DVL1 DVL1 AXIN1 AXIN1 WNT16 WNT16 ONECUT1 ONECUT1 BMI1 BMI1 LIF LIF JAK3 JAK3 PCGF3 PCGF3 SMAD5 SMAD5 AXIN2 AXIN2 INHBE INHBE INHBC INHBC PIK3R2 PIK3R2 WNT8A WNT8A WNT10A WNT10A FZD6 FZD6 MAPK3 MAPK3 AKT1 AKT1 SMARCAD1 SMARCAD1 BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (432 aa)
SKILSki-like protein. (684 aa)
HOXB1Homeobox protein Hox-B1. (302 aa)
PCGF6Polycomb group RING finger protein 6. (349 aa)
ZFHX3Zinc finger homeobox protein 3. (2769 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
OTX1Homeobox protein OTX1. (353 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (394 aa)
POU5F1POU domain transcription factor, class 5. (189 aa)
JAK1Janus kinase 1. (1158 aa)
HOXA1Homeobox protein Hox-A1. (333 aa)
APCAdenomatous polyposis coli protein. (2879 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
APC2Adenomatous polyposis coli protein 2. (2316 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
INHBAInhibin beta A chain. (425 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
ISL1Insulin enhancer protein ISL-1. (349 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
NRASGTPase NRas. (189 aa)
DLX5Homeobox protein DLX-5. (289 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC102279088Uncharacterized protein. (1058 aa)
FGFR4Fibroblast growth factor receptor. (799 aa)
SMAD2Mothers against decapentaplegic homolog. (468 aa)
PAX6Paired box protein Pax-6. (436 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
MYCV-myc avian myelocytomatosis viral oncogene homolog. (436 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
NANOG-2Homeobox protein NANOG. (300 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
IGF1Insulin-like growth factor I. (194 aa)
FZD5Frizzled class receptor 5. (545 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
FGFR1Basic fibroblast growth factor receptor 1. (852 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (650 aa)
PCGF1Polycomb group RING finger protein 1. (259 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
HESX1Homeobox expressed in ES cells 1. (178 aa)
WNT3AWingless-type MMTV integration site family, member 3. (348 aa)
MAPK14Mitogen-activated protein kinase. (369 aa)
SMAD9Mothers against decapentaplegic homolog. (430 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
LOC102274414Left-right determination factor 2. (212 aa)
MAPK12Mitogen-activated protein kinase. (374 aa)
MAPK11Mitogen-activated protein kinase 11. (256 aa)
AKT2RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
NODALNodal-like protein. (346 aa)
CTNNB1Catenin beta-1. (781 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LIFRLeukemia inhibitory factor receptor. (1142 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (479 aa)
FZD7Frizzled class receptor 7. (558 aa)
BMPR2Bone morphogenetic protein receptor type 2. (1038 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
RIF1Replication timing regulatory factor 1. (2465 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
LHX5LIM/homeobox protein Lhx5. (406 aa)
KRASGTPase KRas. (189 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (515 aa)
ESX1Homeobox protein ESX1. (271 aa)
MEIS1Homeobox protein Meis1. (465 aa)
ENSBMUP00000030233Wingless-type MMTV integration site family, member 7. (190 aa)
ENSBMUP00000030236Wingless-type MMTV integration site family, member 7. (154 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
IL6STInterleukin-6 receptor subunit beta. (918 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
PCGF5Polycomb group RING finger protein 5. (256 aa)
DVL1Segment polarity protein dishevelled-like protein DVL-1. (691 aa)
AXIN1Axin-1. (865 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
ONECUT1One cut domain family member. (465 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
LIFLeukemia inhibitory factor. (202 aa)
JAK3Tyrosine-protein kinase. (1133 aa)
PCGF3Polycomb group RING finger protein 3. (242 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
AXIN2Axin-2. (771 aa)
INHBEInhibin beta E chain. (348 aa)
INHBCInhibin beta C chain. (352 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT10AWingless-type MMTV integration site family, member 10. (393 aa)
FZD6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
SMARCAD1Uncharacterized protein. (1029 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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