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GSK3B GSK3B IKBKB IKBKB M91_06687 M91_06687 RELA RELA CD19 CD19 MALT1 MALT1 NFATC3 NFATC3 VAV3 VAV3 NFKBIA NFKBIA MAP2K1 MAP2K1 HRAS HRAS SOS1 SOS1 CD79B CD79B NRAS NRAS PIK3CB PIK3CB FOS FOS CD79A CD79A CR2 CR2 DAPP1 DAPP1 GRB2 GRB2 LOC102273069 LOC102273069 PTPN6 PTPN6 PIK3R1 PIK3R1 SYK SYK RAF1 RAF1 BTK BTK LYN LYN NFKBIE NFKBIE PPP3CC PPP3CC NFKBIB NFKBIB PPP3CA PPP3CA AKT2 AKT2 PIK3CA PIK3CA RASGRP3 RASGRP3 CHUK CHUK INPPL1 INPPL1 BCL10 BCL10 LOC102285474 LOC102285474 MAP2K2 MAP2K2 PIK3R3 PIK3R3 NFKB1 NFKB1 CARD11 CARD11 KRAS KRAS PPP3R1 PPP3R1 PLCG2 PLCG2 PIK3AP1 PIK3AP1 SOS2 SOS2 CD72 CD72 CD81 CD81 RAC2 RAC2 INPP5D INPP5D VAV1 VAV1 PIK3R2 PIK3R2 MAPK3 MAPK3 AKT1 AKT1 PPP3CB PPP3CB IKBKG IKBKG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (432 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
M91_06687Ig heavy chain V region MC101. (200 aa)
RELATranscription factor p65. (549 aa)
CD19B-lymphocyte antigen CD19. (561 aa)
MALT1Uncharacterized protein. (828 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3. (1038 aa)
VAV3Guanine nucleotide exchange factor VAV3. (874 aa)
NFKBIANF-kappa-B inhibitor alpha. (224 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain. (230 aa)
NRASGTPase NRas. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
FOSProto-oncogene c-Fos. (380 aa)
CD79AB-cell antigen receptor complex-associated protein alpha chain. (223 aa)
CR2Complement receptor type 2. (1372 aa)
DAPP1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide. (281 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LOC102273069Uncharacterized protein. (312 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type 6. (597 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
SYKNon-specific protein-tyrosine kinase. (629 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
BTKTyrosine-protein kinase. (659 aa)
LYNTyrosine-protein kinase. (512 aa)
NFKBIENF-kappa-B inhibitor epsilon. (362 aa)
PPP3CCSerine/threonine-protein phosphatase. (587 aa)
NFKBIBNF-kappa-B inhibitor beta. (357 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
AKT2RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
RASGRP3Ras guanyl-releasing protein 3. (692 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (740 aa)
INPPL1Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2. (1259 aa)
BCL10B-cell lymphoma/leukemia 10. (230 aa)
LOC102285474Nuclear factor of activated T-cells, cytoplasmic 1-like. (454 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
CARD11Caspase recruitment domain-containing protein 11. (1131 aa)
KRASGTPase KRas. (189 aa)
PPP3R1Calcineurin subunit B type 1. (188 aa)
PLCG2Phosphoinositide phospholipase C. (1240 aa)
PIK3AP1Phosphoinositide 3-kinase adapter protein 1. (799 aa)
SOS2Son of sevenless-like protein 2. (1272 aa)
CD72B-cell differentiation antigen CD72. (360 aa)
CD81Tetraspanin. (273 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
INPP5DPhosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (1203 aa)
VAV1Proto-oncogene vav. (844 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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