STRINGSTRING
PRKCD PRKCD M91_06687 M91_06687 CFL1 CFL1 LOC102280754 LOC102280754 VAV3 VAV3 PLPP2 PLPP2 ASAP2 ASAP2 CFL2 CFL2 DNM2 DNM2 AMPH AMPH PLD2 PLD2 RPS6KB1 RPS6KB1 WAS WAS DOCK1 DOCK1 MAP2K1 MAP2K1 M91_01832 M91_01832 PLD1 PLD1 PIK3CB PIK3CB ASAP1 ASAP1 MYO10 MYO10 MARCKSL1 MARCKSL1 PLPP3 PLPP3 PIP5K1B PIP5K1B LOC102273069 LOC102273069 LOC102273538 LOC102273538 PIK3R1 PIK3R1 SYK SYK PLA2G6 PLA2G6 SPHK1 SPHK1 RAF1 RAF1 ARPC4 ARPC4 NCF1 NCF1 LYN LYN GAB2 GAB2 ASAP3 ASAP3 HCK HCK ARPC1A ARPC1A CDC42 CDC42 AKT2 AKT2 SPHK2 SPHK2 PIK3CA PIK3CA M91_03436 M91_03436 WASF2 WASF2 WASF1 WASF1 INPPL1 INPPL1 PIP5K1C PIP5K1C PIK3R3 PIK3R3 CRKL CRKL PLA2G4B PLA2G4B PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F ARPC5L ARPC5L VASP VASP PLCG2 PLCG2 ARPC3 ARPC3 ARPC5 ARPC5 ARF6 ARF6 RPS6KB2 RPS6KB2 PLA2G4A PLA2G4A ENSBMUP00000031206 ENSBMUP00000031206 PAK1 PAK1 LIMK2 LIMK2 PIP5K1A PIP5K1A SCIN SCIN RAC2 RAC2 PRKCG PRKCG BIN1 BIN1 INPP5D INPP5D VAV1 VAV1 PRKCA PRKCA PIK3R2 PIK3R2 ARPC2 ARPC2 MAPK3 MAPK3 AKT1 AKT1 PLCG1 PLCG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
M91_06687Ig heavy chain V region MC101. (200 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (205 aa)
LOC102280754High affinity immunoglobulin gamma Fc receptor I. (349 aa)
VAV3Guanine nucleotide exchange factor VAV3. (874 aa)
PLPP2Lipid phosphate phosphohydrolase 2. (300 aa)
ASAP2Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2. (1000 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
DNM2Dynamin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
AMPHAmphiphysin. (686 aa)
PLD2Phospholipase. (933 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1; Belongs to the protein kinase superfamily. (525 aa)
WASWiskott-Aldrich syndrome protein. (514 aa)
DOCK1Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1199 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
M91_01832Protein kinase C epsilon type. (145 aa)
PLD1Phospholipase. (1074 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
ASAP1Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein. (1106 aa)
MYO10Myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
MARCKSL1MARCKS-related protein. (198 aa)
PLPP3Lipid phosphate phosphohydrolase 3. (311 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type-1 beta. (546 aa)
LOC102273069Uncharacterized protein. (312 aa)
LOC102273538Low affinity immunoglobulin gamma Fc region receptor III. (250 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
SYKNon-specific protein-tyrosine kinase. (629 aa)
PLA2G685 kDa calcium-independent phospholipase A2. (805 aa)
SPHK1Sphingosine kinase 1. (475 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
ARPC4Actin-related protein 2/3 complex subunit 4. (188 aa)
NCF1Neutrophil cytosol factor 1. (392 aa)
LYNTyrosine-protein kinase. (512 aa)
GAB2GRB2-associated-binding protein 2. (666 aa)
ASAP3Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein. (869 aa)
HCKTyrosine-protein kinase. (524 aa)
ARPC1AActin-related protein 2/3 complex subunit 1A-like. (279 aa)
CDC42Cell division control protein 42-like protein. (191 aa)
AKT2RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SPHK2Sphingosine kinase 2. (653 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
M91_03436Endo/exonuclease/phosphatase domain-containing protein. (345 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2. (493 aa)
WASF1Wiskott-Aldrich syndrome protein family member 1. (559 aa)
INPPL1Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2. (1259 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type-1 gamma. (668 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CRKLCrk-like protein. (302 aa)
PLA2G4BPhospholipase A2. (784 aa)
PLA2G4EPhospholipase A2. (860 aa)
PLA2G4DPhospholipase A2. (808 aa)
PLA2G4FPhospholipase A2. (844 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (164 aa)
VASPVasodilator-stimulated phosphoprotein. (383 aa)
PLCG2Phosphoinositide phospholipase C. (1240 aa)
ARPC3Actin-related protein 2/3 complex subunit 3. (178 aa)
ARPC5Actin related protein 2/3 complex, subunit 5. (151 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RPS6KB2Ribosomal protein S6 kinase beta. (347 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSBMUP00000031206Dedicator of cytokinesis protein 1-like. (410 aa)
PAK1Non-specific serine/threonine protein kinase. (552 aa)
LIMK2LIM domain kinase 2. (658 aa)
PIP5K1APutative PIP5K1A and PSMD4-like protein. (562 aa)
SCINAdseverin. (715 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
BIN1Myc box-dependent-interacting protein 1. (602 aa)
INPP5DPhosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1. (1203 aa)
VAV1Proto-oncogene vav. (844 aa)
PRKCAProtein kinase C alpha type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (614 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
ARPC2Actin related protein 2/3 complex, subunit 2. (413 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
PLCG1Phosphoinositide phospholipase C. (1277 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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