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GSK3B GSK3B SRC SRC RELA RELA SOCS7 SOCS7 LOC102270241 LOC102270241 LOC102270532 LOC102270532 TNFSF11 TNFSF11 PRLR PRLR SOCS5 SOCS5 JAK2 JAK2 LOC102272860 LOC102272860 LOC102271434 LOC102271434 M91_12163 M91_12163 CCND1 CCND1 LOC102271714 LOC102271714 LOC102272287 LOC102272287 MAP2K1 MAP2K1 SOCS2 SOCS2 HRAS HRAS SOS1 SOS1 SLC2A2 SLC2A2 NRAS NRAS PIK3CB PIK3CB FOS FOS ELF5 ELF5 GRB2 GRB2 SOCS3 SOCS3 SOCS4 SOCS4 PIK3R1 PIK3R1 RAF1 RAF1 SHC1 SHC1 LHCGR LHCGR MAPK9 MAPK9 CGA CGA MAPK13 MAPK13 MAPK14 MAPK14 ESR2 ESR2 IRF1 IRF1 LHB LHB MAPK12 MAPK12 MAPK11 MAPK11 AKT2 AKT2 STAT1 STAT1 STAT3 STAT3 STAT5A STAT5A STAT5B STAT5B LOC102269208 LOC102269208 PIK3CA PIK3CA SHC3 SHC3 GALT GALT MAP2K2 MAP2K2 PIK3R3 PIK3R3 FOXO3 FOXO3 NFKB1 NFKB1 KRAS KRAS MAPK8 MAPK8 CISH CISH LOC102274562 LOC102274562 PRL PRL SOS2 SOS2 MAPK10 MAPK10 SHC4 SHC4 ESR1 ESR1 LOC102276948 LOC102276948 PIK3R2 PIK3R2 CCND2 CCND2 GCK GCK MAPK3 MAPK3 AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (432 aa)
SRCTyrosine-protein kinase. (559 aa)
RELATranscription factor p65. (549 aa)
SOCS7Suppressor of cytokine signaling 7. (576 aa)
LOC102270241Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
LOC102270532Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (509 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (244 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (581 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
LOC102272860Chorionic somatomammotropin hormone 2. (259 aa)
LOC102271434Placental prolactin-related protein 1. (259 aa)
M91_12163Uncharacterized protein. (238 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (67 aa)
LOC102271714Uncharacterized protein. (236 aa)
LOC102272287Placental prolactin-related protein 4. (240 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
SLC2A2MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2. (522 aa)
NRASGTPase NRas. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
FOSProto-oncogene c-Fos. (380 aa)
ELF5ETS-related transcription factor Elf-5. (255 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
SHC1SHC-transforming protein 1. (501 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (699 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
MAPK14Mitogen-activated protein kinase. (369 aa)
ESR2Estrogen receptor beta. (527 aa)
IRF1Interferon regulatory factor. (322 aa)
LHBLuteinizing hormone beta polypeptide. (141 aa)
MAPK12Mitogen-activated protein kinase. (374 aa)
MAPK11Mitogen-activated protein kinase 11. (256 aa)
AKT2RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa)
STAT1Signal transducer and activator of transcription. (817 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT5BSignal transducer and activator of transcription 5B. (787 aa)
LOC102269208Placental prolactin-related protein 3. (278 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
SHC3SHC-transforming protein 3. (105 aa)
GALTGalactose-1-phosphate uridylyltransferase. (379 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
FOXO3Forkhead box protein O3. (453 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
KRASGTPase KRas. (189 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
CISHCytokine-inducible SH2-containing protein. (254 aa)
LOC102274562Chorionic somatomammotropin hormone 1. (236 aa)
PRLProlactin. (230 aa)
SOS2Son of sevenless-like protein 2. (1272 aa)
MAPK10Mitogen-activated protein kinase. (370 aa)
SHC4SHC-transforming protein 4. (630 aa)
ESR1Estrogen receptor. (310 aa)
LOC102276948Uncharacterized protein. (238 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (284 aa)
GCKPhosphotransferase. (466 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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