Your Input: | |
| | GSK3B | Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (432 aa) |
| | DIO3 | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (131 aa) |
| | SRC | Tyrosine-protein kinase. (559 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (2546 aa) |
| | ATP2A1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (997 aa) |
| | PLCD3 | Phosphoinositide phospholipase C. (783 aa) |
| | SIN3A | Paired amphipathic helix protein Sin3a. (1274 aa) |
| | GATA4 | Transcription factor GATA-4. (236 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (850 aa) |
| | CREBBP | CREB-binding protein. (2203 aa) |
| | SLCO1C1 | Solute carrier organic anion transporter family member 1C1. (729 aa) |
| | MED24 | Mediator of RNA polymerase II transcription subunit 24. (997 aa) |
| | THRA | Thyroid hormone receptor alpha. (511 aa) |
| | PFKP | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (783 aa) |
| | PLCZ1 | Phosphoinositide phospholipase C. (637 aa) |
| | MED27 | Mediator of RNA polymerase II transcription subunit 27. (311 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2043 aa) |
| | HDAC2 | Histone deacetylase 1/2. (488 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (67 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1. (393 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (182 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1441 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa) |
| | RCAN2 | Calcipressin-2. (243 aa) |
| | MYC | V-myc avian myelocytomatosis viral oncogene homolog. (436 aa) |
| | ATP1A3 | Sodium/potassium-transporting ATPase subunit alpha. (1014 aa) |
| | M91_02843 | GTP-binding protein Rheb. (79 aa) |
| | NCOA3 | Nuclear receptor coactivator 3. (1412 aa) |
| | RXRB | Retinoic acid receptor RXR-beta. (529 aa) |
| | HDAC1 | Histone deacetylase 1. (482 aa) |
| | KAT2B | Histone acetyltransferase KAT2B. (832 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (668 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2. (492 aa) |
| | ATP2A3 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1044 aa) |
| | MED13L | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2209 aa) |
| | MED14 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1443 aa) |
| | THRB | Thyroid hormone receptor beta. (476 aa) |
| | NOTCH2 | Uncharacterized protein. (2471 aa) |
| | FXYD2 | FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (192 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (829 aa) |
| | ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha. (1020 aa) |
| | ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha. (1030 aa) |
| | PFKL | 6-phosphofructokinase, liver type. (751 aa) |
| | SLC16A2 | Monocarboxylate transporter 8. (605 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2434 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | BAD | Bcl2 antagonist of cell death. (168 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1. (566 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa) |
| | AKT2 | RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | STAT1 | Signal transducer and activator of transcription. (817 aa) |
| | RXRG | Retinoic acid receptor RXR-gamma. (463 aa) |
| | EP300 | E1A binding protein p300. (2371 aa) |
| | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha. (1021 aa) |
| | MED30 | Mediator of RNA polymerase II transcription subunit 30. (177 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa) |
| | KAT2A | Histone acetyltransferase KAT2A. (837 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (818 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | SLC16A10 | Monocarboxylate transporter 10. (515 aa) |
| | MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (651 aa) |
| | TSC2 | Tuberous sclerosis 2. (1812 aa) |
| | FOXO1 | Forkhead box protein O1. (468 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (1785 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | PLCD1 | Phosphoinositide phospholipase C. (663 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (349 aa) |
| | KRAS | GTPase KRas. (189 aa) |
| | PLN | Phospholamban. (52 aa) |
| | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta. (303 aa) |
| | PLCG2 | Phosphoinositide phospholipase C. (1240 aa) |
| | TBC1D4 | TBC1 domain family member 4. (1295 aa) |
| | ATP1B3 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (88 aa) |
| | ATP2A2 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2. (1037 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | MED12L | Mediator of RNA polymerase II transcription subunit 12. (2147 aa) |
| | ATP1B2 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (285 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (386 aa) |
| | PLCB1 | Phosphoinositide phospholipase C. (1183 aa) |
| | DIO1 | Type I thyroxine 5'-deiodinase. (248 aa) |
| | ATP1B4 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (354 aa) |
| | HDAC3 | Histone deacetylase 3. (428 aa) |
| | ESR1 | Estrogen receptor. (310 aa) |
| | ITGAV | Integrin subunit alpha V. (986 aa) |
| | NOTCH4 | Notch 4. (642 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa) |
| | ITGB3 | Integrin beta. (788 aa) |
| | MED12 | Mediator of RNA polymerase II transcription subunit 12. (2003 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha. (823 aa) |
| | PFKFB2 | 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2. (535 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (414 aa) |
| | PRKCA | Protein kinase C alpha type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (614 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa) |
| | NCOA2 | Nuclear receptor coactivator 2. (1461 aa) |
| | PLCD4 | Phosphoinositide phospholipase C. (791 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa) |
| | AKT1 | RAC serine/threonine-protein kinase. (421 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | PLCG1 | Phosphoinositide phospholipase C. (1277 aa) |
| | MYH7 | Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1989 aa) |
