STRINGSTRING
GNAI1 GNAI1 ADCY9 ADCY9 PTGER3 PTGER3 GNAI3 GNAI3 PTGS1 PTGS1 TSHB TSHB ADCY8 ADCY8 PNPLA2 PNPLA2 ADRB3 ADRB3 ADCY1 ADCY1 ADCY3 ADCY3 PIK3CB PIK3CB ADORA1 ADORA1 PLIN1 PLIN1 LIPE LIPE ADCY4 ADCY4 PRKG1 PRKG1 PIK3R1 PIK3R1 M91_02760 M91_02760 LOC102272527 LOC102272527 NPY NPY CGA CGA NPPA NPPA IRS1 IRS1 AKT2 AKT2 PLAAT3 PLAAT3 FABP4 FABP4 PIK3CA PIK3CA AQP7 AQP7 ABHD5 ABHD5 ADRB2 ADRB2 PIK3R3 PIK3R3 PRKACA PRKACA PRKG2 PRKG2 LOC102270503 LOC102270503 LOC102266153 LOC102266153 IRS4 IRS4 TSHR TSHR GNAI2 GNAI2 LOC102285991 LOC102285991 PTGS2 PTGS2 ADCY6 ADCY6 NPY1R NPY1R PRKACB PRKACB PIK3R2 PIK3R2 ADCY7 ADCY7 INSR INSR AKT1 AKT1 NPR1 NPR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNAI1Guanine nucleotide-binding protein G(i) subunit alpha. (354 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype. (387 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PTGS1Prostaglandin G/H synthase 1. (635 aa)
TSHBThyrotropin subunit beta. (139 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1251 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (501 aa)
ADRB3Beta-3 adrenergic receptor. (396 aa)
ADCY1Adenylate cyclase 1. (310 aa)
ADCY3Adenylate cyclase type 3. (1145 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
PLIN1Perilipin; Belongs to the perilipin family. (516 aa)
LIPEHormone-sensitive lipase. (799 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PRKG1cGMP-dependent protein kinase 1. (686 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
M91_02760HRAS-like suppressor 2. (180 aa)
LOC102272527HRAS-like suppressor 3. (159 aa)
NPYNeuropeptide Y. (97 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
NPPAAtrial natriuretic factor. (188 aa)
IRS1Insulin receptor substrate 1. (1237 aa)
AKT2RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PLAAT3Group XVI phospholipase A2. (162 aa)
FABP4Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
AQP7Aquaporin-7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (330 aa)
ABHD51-acylglycerol-3-phosphate O-acyltransferase ABHD5. (348 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (349 aa)
PRKG2cGMP-dependent protein kinase 2. (710 aa)
LOC102270503CGMP-dependent protein kinase 2-like. (107 aa)
LOC102266153Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (394 aa)
IRS4Insulin receptor substrate 4. (1207 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (697 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
LOC102285991Phosphodiesterase. (626 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
ADCY6Adenylate cyclase 6. (1163 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1097 aa)
INSRInsulin receptor. (1382 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
NPR1Guanylate cyclase. (1058 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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