STRINGSTRING
MMP17 MMP17 GATA3 GATA3 ATF4 ATF4 GNAI1 GNAI1 PLCB2 PLCB2 VDR VDR GCM1 GCM1 TNFSF11 TNFSF11 GCM2 GCM2 ADCY9 ADCY9 BCL2 BCL2 GNAI3 GNAI3 TRPV5 TRPV5 ARRB1 ARRB1 ARRB2 ARRB2 MMP24 MMP24 PLD2 PLD2 LRP5L LRP5L ADCY8 ADCY8 PDE4D PDE4D MAP2K1 MAP2K1 ADCY1 ADCY1 ADCY3 ADCY3 PLD1 PLD1 SLC34A1 SLC34A1 FOS FOS SLC9A3R1 SLC9A3R1 ADCY4 ADCY4 RXRB RXRB SLC34A2 SLC34A2 PTH PTH LRP6 LRP6 CREB1 CREB1 MMP16 MMP16 RAF1 RAF1 PDE4B PDE4B FGFR1 FGFR1 PDE4C PDE4C CDKN1A CDKN1A GNA11 GNA11 PDE4A PDE4A KL KL MMP25 MMP25 RHOA RHOA CASR CASR PLCB3 PLCB3 MEF2D MEF2D HBEGF HBEGF CREB3L2 CREB3L2 LOC102269868 LOC102269868 ITPR1 ITPR1 MEF2A MEF2A RXRG RXRG ARHGEF11 ARHGEF11 CYP24A1 CYP24A1 GNAQ GNAQ PTH1R PTH1R CREB3L3 CREB3L3 PRKACA PRKACA SOST SOST NACA NACA MMP14 MMP14 AKAP13 AKAP13 LOC102266153 LOC102266153 CREB5 CREB5 GNA12 GNA12 GNAI2 GNAI2 SP1 SP1 PLCB1 PLCB1 ITPR2 ITPR2 CREB3L1 CREB3L1 ADCY6 ADCY6 NR4A2 NR4A2 ATF6B ATF6B CREB3 CREB3 PRKACB PRKACB PRKCG PRKCG MMP13 MMP13 ATF2 ATF2 CYP27B1 CYP27B1 GNA13 GNA13 PRKCA PRKCA ADCY7 ADCY7 ARAF ARAF EGR1 EGR1 MAPK3 MAPK3 CREB3L4 CREB3L4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP17Matrix metalloproteinase-17. (594 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (348 aa)
GNAI1Guanine nucleotide-binding protein G(i) subunit alpha. (354 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
VDRVitamin D3 receptor. (425 aa)
GCM1Chorion-specific transcription factor GCMa. (433 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (244 aa)
GCM2Chorion-specific transcription factor GCMb. (507 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
BCL2Apoptosis regulator Bcl-2. (225 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
TRPV5Transient receptor putative cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (731 aa)
ARRB1Beta-arrestin-1. (429 aa)
ARRB2Arrestin beta 2. (401 aa)
MMP24Matrix metalloproteinase-24. (573 aa)
PLD2Phospholipase. (933 aa)
LRP5LLow-density lipoprotein receptor-related protein 5. (251 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1251 aa)
PDE4DPhosphodiesterase. (808 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
ADCY1Adenylate cyclase 1. (310 aa)
ADCY3Adenylate cyclase type 3. (1145 aa)
PLD1Phospholipase. (1074 aa)
SLC34A1Sodium-dependent phosphate transport protein 2A. (615 aa)
FOSProto-oncogene c-Fos. (380 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (204 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
RXRBRetinoic acid receptor RXR-beta. (529 aa)
SLC34A2Sodium-dependent phosphate transport protein 2B. (758 aa)
PTHParathyroid hormone. (111 aa)
LRP6Low-density lipoprotein receptor-related protein 6. (1613 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (341 aa)
MMP16Matrix metalloproteinase-16. (607 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
PDE4BPhosphodiesterase. (570 aa)
FGFR1Basic fibroblast growth factor receptor 1. (852 aa)
PDE4CCAMP-specific phosphodiesterase 4. (705 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (161 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
PDE4APhosphodiesterase. (822 aa)
KLKlotho. (1012 aa)
MMP25Matrix metalloproteinase-25 (membrane-inserted). (152 aa)
RHOATransforming protein RhoA. (193 aa)
CASRCalcium sensing receptor. (1081 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
MEF2DMyocyte-specific enhancer factor 2D. (501 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
LOC102269868Receptor protein-tyrosine kinase. (722 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2757 aa)
MEF2AMyocyte-specific enhancer factor 2A. (498 aa)
RXRGRetinoic acid receptor RXR-gamma. (463 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1560 aa)
CYP24A11,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
PTH1RParathyroid hormone 1 receptor. (575 aa)
CREB3L3CAMP responsive element binding protein 3 like 3. (456 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (349 aa)
SOSTSclerostin. (212 aa)
NACANascent polypeptide-associated complex subunit alpha, muscle-specific form. (228 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
AKAP13A-kinase anchor protein 13. (1418 aa)
LOC102266153Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (394 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (508 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (291 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
SP1Transcription factor Sp1. (779 aa)
PLCB1Phosphoinositide phospholipase C. (1183 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (520 aa)
ADCY6Adenylate cyclase 6. (1163 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (707 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (365 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
MMP13Collagenase 3. (471 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (505 aa)
CYP27B125-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
PRKCAProtein kinase C alpha type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (614 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1097 aa)
ARAFSerine/threonine-protein kinase A-Raf. (611 aa)
EGR1Early growth response protein 1. (540 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4. (393 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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