STRINGSTRING
CCNA2 CCNA2 IKBKB IKBKB MTOR MTOR RELA RELA LOC102280754 LOC102280754 PPARD PPARD RARA RARA PIM2 PIM2 RPS6KB1 RPS6KB1 CCND1 CCND1 MAP2K1 MAP2K1 HRAS HRAS SOS1 SOS1 EIF4EBP1 EIF4EBP1 NRAS NRAS PIK3CB PIK3CB MYC MYC ZBTB16 ZBTB16 GRB2 GRB2 PIK3R1 PIK3R1 RAF1 RAF1 RUNX1 RUNX1 RUNX1T1 RUNX1T1 CCNA1 CCNA1 BAD BAD CSF2 CSF2 LOC102275760 LOC102275760 CSF1R CSF1R PML PML CD14 CD14 AKT2 AKT2 PIM1 PIM1 STAT3 STAT3 TCF7L2 TCF7L2 STAT5A STAT5A STAT5B STAT5B PIK3CA PIK3CA PER2 PER2 JUP JUP CHUK CHUK CEBPE CEBPE DUSP6 DUSP6 LEF1 LEF1 MAP2K2 MAP2K2 PIK3R3 PIK3R3 NFKB1 NFKB1 KRAS KRAS KIT KIT MPO MPO SOS2 SOS2 RPS6KB2 RPS6KB2 FLT3 FLT3 SPI1 SPI1 ITGAM ITGAM TCF7L1 TCF7L1 PIK3R2 PIK3R2 ARAF ARAF MAPK3 MAPK3 AKT1 AKT1 BCL2A1 BCL2A1 IKBKG IKBKG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNA2Cyclin-A2; Belongs to the cyclin family. (417 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
MTORSerine/threonine-protein kinase mTOR. (2546 aa)
RELATranscription factor p65. (549 aa)
LOC102280754High affinity immunoglobulin gamma Fc receptor I. (349 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
RARARetinoic acid receptor alpha. (478 aa)
PIM2Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily. (311 aa)
RPS6KB1Ribosomal protein S6 kinase beta-1; Belongs to the protein kinase superfamily. (525 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (67 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
HRASHRas proto-oncogene, GTPase. (182 aa)
SOS1Son of sevenless-like protein 1. (1333 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa)
NRASGTPase NRas. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
MYCV-myc avian myelocytomatosis viral oncogene homolog. (436 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (671 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha. (730 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (668 aa)
RUNX1Runt-related transcription factor 1. (491 aa)
RUNX1T1Protein CBFA2T1. (614 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (421 aa)
BADBcl2 antagonist of cell death. (168 aa)
CSF2Uncharacterized protein. (143 aa)
LOC102275760Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (144 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (958 aa)
PMLPutative transcription factor PML. (665 aa)
CD14Monocyte differentiation antigen CD14. (383 aa)
AKT2RAC-beta serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PIM1Proto-oncogene serine/threonine-protein kinase pim-1. (309 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
TCF7L2Transcription factor 7-like 2. (536 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT5BSignal transducer and activator of transcription 5B. (787 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1072 aa)
PER2Period circadian protein-like protein 2. (1291 aa)
JUPJunction plakoglobin. (745 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (740 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
LEF1Lymphoid enhancer-binding factor 1. (414 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (973 aa)
KRASGTPase KRas. (189 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
MPOMyeloperoxidase. (712 aa)
SOS2Son of sevenless-like protein 2. (1272 aa)
RPS6KB2Ribosomal protein S6 kinase beta. (347 aa)
FLT3FL cytokine receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
SPI1Transcription factor PU.1. (333 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
TCF7L1Transcription factor 7-like 1. (575 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (688 aa)
ARAFSerine/threonine-protein kinase A-Raf. (611 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (377 aa)
AKT1RAC serine/threonine-protein kinase. (421 aa)
BCL2A1Bcl-2-related protein A1. (175 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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