(84 nodes) Unfolded protein binding, and Chaperone binding network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF24396	Uncharacterized protein, isoform B. (716 aa)
	DanaGF23468	Uncharacterized protein, isoform B. (662 aa)
	DanaGF17351	Uncharacterized protein, isoform B. (681 aa)
	DanaGF15175	Uncharacterized protein, isoform B. (350 aa)
	DanaGF12282	Uncharacterized protein, isoform B. (730 aa)
	DanaGF13077	Uncharacterized protein, isoform D. (518 aa)
	DanaGF24591	Uncharacterized protein, isoform B. (837 aa)
	DanaGF16232	Uncharacterized protein, isoform B. (375 aa)
	DanaGF27773	Rhomboid domain-containing protein; Belongs to the peptidase S54 family. (330 aa)
	DanaGF17599	Uncharacterized protein, isoform A. (403 aa)
	DanaGF18161	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (194 aa)
	DanaGF18192	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (545 aa)
	DanaGF18855	Uncharacterized protein. (170 aa)
	DanaGF16152	Uncharacterized protein. (557 aa)
	DanaGF17796	TPR_REGION domain-containing protein. (237 aa)
	DanaGF18385	Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
	DanaGF18384	Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
	DanaGF17918	Uncharacterized protein, isoform A. (94 aa)
	DanaGF17067	T-complex protein 1 subunit gamma. (544 aa)
	DanaGF17965	Uncharacterized protein; Belongs to the heat shock protein 70 family. (643 aa)
	DanaGF18534	Uncharacterized protein. (242 aa)
	DanaGF17992	Uncharacterized protein. (614 aa)
	DanaGF10450	J domain-containing protein. (354 aa)
	DanaGF10465	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (138 aa)
	DanaGF23951	Uncharacterized protein. (143 aa)
	DanaGF24491	Phosducin domain-containing protein. (240 aa)
	DanaGF20110	HATPase_c domain-containing protein. (716 aa)
	DanaGF10164	TPR_REGION domain-containing protein. (2478 aa)
	DanaGF23740	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (195 aa)
	DanaGF10689	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (174 aa)
	DanaGF23739	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
	DanaGF23738	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (472 aa)
	DanaGF10691	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (190 aa)
	DanaGF10692	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (219 aa)
	DanaGF10722	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1005 aa)
	DanaGF10728	Uncharacterized protein, isoform C. (267 aa)
	DanaGF24836	Uncharacterized protein. (389 aa)
	DanaGF24761	Uncharacterized protein. (611 aa)
	DanaGF24191	Uncharacterized protein; Belongs to the heat shock protein 70 family. (513 aa)
	DanaGF23604	Uncharacterized protein. (125 aa)
	DanaGF25145	Uncharacterized protein. (415 aa)
	DanaGF24052	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family. (638 aa)
	DanaGF23491	Uncharacterized protein, isoform A. (568 aa)
	DanaGF23490	J domain-containing protein. (130 aa)
	DanaGF24628	Uncharacterized protein; Belongs to the GroES chaperonin family. (104 aa)
	DanaGF12842	Uncharacterized protein. (232 aa)
	DanaGF13472	J domain-containing protein. (222 aa)
	DanaGF11360	Uncharacterized protein; Belongs to the heat shock protein 70 family. (686 aa)
	DanaGF11356	Uncharacterized protein. (292 aa)
	DanaGF12562	Uncharacterized protein. (546 aa)
	DanaGF11829	Uncharacterized protein, isoform A; Belongs to the small heat shock protein (HSP20) family. (187 aa)
	DanaGF13619	Uncharacterized protein. (546 aa)
	DanaGF12298	Uncharacterized protein. (542 aa)
	DanaGF13703	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (224 aa)
	DanaGF12761	Uncharacterized protein, isoform A. (351 aa)
	DanaGF13259	Uncharacterized protein. (197 aa)
	DanaGF13807	Uncharacterized protein. (691 aa)
	DanaGF15792	Uncharacterized protein. (289 aa)
	DanaGF14502	Uncharacterized protein. (126 aa)
	DanaGF15458	Uncharacterized protein. (652 aa)
	DanaGF15575	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (576 aa)
	DanaGF15639	Uncharacterized protein, isoform A. (710 aa)
	DanaGF15647	Uncharacterized protein. (442 aa)
	DanaGF15661	T-complex protein 1 subunit delta. (533 aa)
	DanaGF15674	Uncharacterized protein. (86 aa)
	DanaGF14673	Peptidylprolyl isomerase. (440 aa)
	DanaGF14138	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (216 aa)
	DanaGF15771	ATP-dependent Clp protease proteolytic subunit. (252 aa)
	DanaGF20294	Uncharacterized protein, isoform A; Belongs to the chaperonin (HSP60) family. (582 aa)
	DanaGF20408	Uncharacterized protein, isoform A; Belongs to the small heat shock protein (HSP20) family. (193 aa)
	DanaGF23063	CS domain-containing protein. (182 aa)
	DanaGF23172	Uncharacterized protein. (651 aa)
	DanaGF23034	TPR_REGION domain-containing protein. (521 aa)
	DanaGF21442	Aha1_N domain-containing protein. (356 aa)
	DanaGF20641	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (651 aa)
	DanaGF20636	TPR_REGION domain-containing protein. (489 aa)
	DanaGF21637	Uncharacterized protein. (560 aa)
	DanaGF19478	Uncharacterized protein. (532 aa)
	DanaGF19555	J domain-containing protein. (334 aa)
	DanaGF19192	Uncharacterized protein. (535 aa)
	DanaGF21747	Uncharacterized protein, isoform A. (301 aa)
	DanaGF19641	Uncharacterized protein. (259 aa)
	DanaGF19283	Uncharacterized protein. (167 aa)
	DanaGF15894	Uncharacterized protein. (167 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10164	DanaGF12842	B3M6A5	B3MCA4	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.452
DanaGF10164	DanaGF13807	B3M6A5	B3MJ48	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.761
DanaGF10164	DanaGF14673	B3M6A5	B3MP22	TPR_REGION domain-containing protein.	Peptidylprolyl isomerase.	0.402
DanaGF10164	DanaGF15647	B3M6A5	B3MNG5	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.492
DanaGF10164	DanaGF15894	B3M6A5	B3N2Y5	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.452
DanaGF10164	DanaGF17599	B3M6A5	B3LX79	TPR_REGION domain-containing protein.	Uncharacterized protein, isoform A.	0.492
DanaGF10164	DanaGF17918	B3M6A5	B3M2C2	TPR_REGION domain-containing protein.	Uncharacterized protein, isoform A.	0.452
DanaGF10164	DanaGF17965	B3M6A5	B3M2S4	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.452
DanaGF10164	DanaGF18384	B3M6A5	B3M0Z7	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.452
DanaGF10164	DanaGF18385	B3M6A5	B3M0Z4	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.452
DanaGF10164	DanaGF19283	B3M6A5	B3N2S6	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.452
DanaGF10164	DanaGF20110	B3M6A5	B3M5T3	TPR_REGION domain-containing protein.	HATPase_c domain-containing protein.	0.761
DanaGF10164	DanaGF21442	B3M6A5	B3MTZ5	TPR_REGION domain-containing protein.	Aha1_N domain-containing protein.	0.624
DanaGF10164	DanaGF23063	B3M6A5	B3MTT1	TPR_REGION domain-containing protein.	CS domain-containing protein.	0.688
DanaGF10164	DanaGF23491	B3M6A5	B3MAK5	TPR_REGION domain-containing protein.	Uncharacterized protein, isoform A.	0.492
DanaGF10164	DanaGF24052	B3M6A5	B3MAG9	TPR_REGION domain-containing protein.	Uncharacterized protein, isoform A; Belongs to the heat shock protein 70 family.	0.452
DanaGF10164	DanaGF24591	B3M6A5	A0A0P8XTQ3	TPR_REGION domain-containing protein.	Uncharacterized protein, isoform B.	0.673
DanaGF10164	DanaGF24836	B3M6A5	B3M7A2	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.497
DanaGF10164	DanaGF25145	B3M6A5	B3MAB3	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.508
DanaGF10450	DanaGF10691	B3M3N1	B3M6F3	J domain-containing protein.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.481