(5 nodes) Sterol metabolism, and Cholesterol biosynthetic process network (Drosophila ananassae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	DanaGF15902	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (390 aa)
	DanaGF16258	3-hydroxy-3-methylglutaryl coenzyme A reductase. (926 aa)
	DanaGF11467	Mevalonate kinase. (390 aa)
	DanaGF13593	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (463 aa)
	DanaGF15482	Uncharacterized protein. (186 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF11467	DanaGF13593	B3MCU1	B3MFN4	Mevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.922
DanaGF11467	DanaGF15482	B3MCU1	B3ML74	Mevalonate kinase.	Uncharacterized protein.	0.989
DanaGF11467	DanaGF15902	B3MCU1	A0A0P8ZJJ9	Mevalonate kinase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.997
DanaGF11467	DanaGF16258	B3MCU1	B3LY57	Mevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.992
DanaGF13593	DanaGF11467	B3MFN4	B3MCU1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Mevalonate kinase.	0.922
DanaGF13593	DanaGF15482	B3MFN4	B3ML74	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.738
DanaGF13593	DanaGF15902	B3MFN4	A0A0P8ZJJ9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.941
DanaGF13593	DanaGF16258	B3MFN4	B3LY57	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.999
DanaGF15482	DanaGF11467	B3ML74	B3MCU1	Uncharacterized protein.	Mevalonate kinase.	0.989
DanaGF15482	DanaGF13593	B3ML74	B3MFN4	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.738
DanaGF15482	DanaGF15902	B3ML74	A0A0P8ZJJ9	Uncharacterized protein.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.788
DanaGF15482	DanaGF16258	B3ML74	B3LY57	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.603
DanaGF15902	DanaGF11467	A0A0P8ZJJ9	B3MCU1	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	Mevalonate kinase.	0.997
DanaGF15902	DanaGF13593	A0A0P8ZJJ9	B3MFN4	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.941
DanaGF15902	DanaGF15482	A0A0P8ZJJ9	B3ML74	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	Uncharacterized protein.	0.788
DanaGF15902	DanaGF16258	A0A0P8ZJJ9	B3LY57	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.702
DanaGF16258	DanaGF11467	B3LY57	B3MCU1	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Mevalonate kinase.	0.992
DanaGF16258	DanaGF13593	B3LY57	B3MFN4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.999
DanaGF16258	DanaGF15482	B3LY57	B3ML74	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein.	0.603
DanaGF16258	DanaGF15902	B3LY57	A0A0P8ZJJ9	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.702