(15 nodes) Sphingolipid metabolism network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF26778	Uncharacterized protein. (415 aa)
	DanaGF26652	Endo/exonuclease/phosphatase domain-containing protein. (431 aa)
	DanaGF17432	Uncharacterized protein. (332 aa)
	DanaGF17718	Uncharacterized protein, isoform A. (690 aa)
	DanaGF24262	DAGKc domain-containing protein. (659 aa)
	DanaGF13285	Uncharacterized protein. (433 aa)
	DanaGF13423	Uncharacterized protein, isoform A. (545 aa)
	DanaGF11387	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (719 aa)
	DanaGF11943	Uncharacterized protein, isoform A. (468 aa)
	DanaGF15415	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (968 aa)
	DanaGF14446	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (299 aa)
	DanaGF15596	Lipid_DES domain-containing protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. (321 aa)
	DanaGF22903	Neutral ceramidase. (706 aa)
	DanaGF22547	Uncharacterized protein, isoform A. (644 aa)
	DanaGF18993	Aminotran_1_2 domain-containing protein. (577 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF11387	DanaGF13285	B3MDM0	B3MBH6	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Uncharacterized protein.	0.918
DanaGF11387	DanaGF14446	B3MDM0	B3ML29	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.910
DanaGF11387	DanaGF15415	B3MDM0	B3MKK0	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.904
DanaGF11387	DanaGF15596	B3MDM0	B3MMQ3	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Lipid_DES domain-containing protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.	0.904
DanaGF11387	DanaGF17718	B3MDM0	B3LZJ5	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Uncharacterized protein, isoform A.	0.913
DanaGF11387	DanaGF22903	B3MDM0	B3MTB9	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Neutral ceramidase.	0.913
DanaGF11387	DanaGF26652	B3MDM0	A0A0P9AJV3	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Endo/exonuclease/phosphatase domain-containing protein.	0.926
DanaGF11387	DanaGF26778	B3MDM0	A0A0P8YKM5	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.	Uncharacterized protein.	0.912
DanaGF11943	DanaGF13285	B3MDS6	B3MBH6	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.804
DanaGF11943	DanaGF13423	B3MDS6	B3MD62	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.583
DanaGF11943	DanaGF14446	B3MDS6	B3ML29	Uncharacterized protein, isoform A.	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.	0.586
DanaGF11943	DanaGF15415	B3MDS6	B3MKK0	Uncharacterized protein, isoform A.	Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.	0.573
DanaGF11943	DanaGF15596	B3MDS6	B3MMQ3	Uncharacterized protein, isoform A.	Lipid_DES domain-containing protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.	0.627
DanaGF11943	DanaGF17432	B3MDS6	B3LWJ6	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.989
DanaGF11943	DanaGF17718	B3MDS6	B3LZJ5	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.821
DanaGF11943	DanaGF18993	B3MDS6	B3N2E8	Uncharacterized protein, isoform A.	Aminotran_1_2 domain-containing protein.	0.997
DanaGF11943	DanaGF22547	B3MDS6	B3MVR5	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.528
DanaGF11943	DanaGF22903	B3MDS6	B3MTB9	Uncharacterized protein, isoform A.	Neutral ceramidase.	0.722
DanaGF11943	DanaGF24262	B3MDS6	B3M7F2	Uncharacterized protein, isoform A.	DAGKc domain-containing protein.	0.749
DanaGF11943	DanaGF26652	B3MDS6	A0A0P9AJV3	Uncharacterized protein, isoform A.	Endo/exonuclease/phosphatase domain-containing protein.	0.637