(23 nodes) Transmembrane receptor protein serine/threonine kinase signaling pathway, and E3 ubiquitin-protein ligase, SMURF1 type network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF13635	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (575 aa)
	DanaGF20585	Uncharacterized protein, isoform B. (629 aa)
	DanaGF20577	Mothers against decapentaplegic homolog. (581 aa)
	DanaGF20147	TGF_BETA_2 domain-containing protein. (738 aa)
	DanaGF17542	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	DanaGF17083	Mothers against decapentaplegic homolog. (568 aa)
	DanaGF10539	Uncharacterized protein, isoform D. (990 aa)
	DanaGF20060	Uncharacterized protein. (266 aa)
	DanaGF24409	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (913 aa)
	DanaGF10376	Uncharacterized protein. (384 aa)
	DanaGF12817	Zinc finger FYVE domain-containing protein. (1347 aa)
	DanaGF12511	TGF_BETA_2 domain-containing protein. (454 aa)
	DanaGF12621	Uncharacterized protein, isoform A. (867 aa)
	DanaGF12221	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
	DanaGF11657	Uncharacterized protein. (1047 aa)
	DanaGF14597	Uncharacterized protein. (963 aa)
	DanaGF14981	Uncharacterized protein, isoform A. (593 aa)
	DanaGF15519	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DanaGF20979	Mothers against decapentaplegic homolog. (471 aa)
	DanaGF22974	Mothers against decapentaplegic homolog. (770 aa)
	DanaGF22823	Uncharacterized protein, isoform C. (1220 aa)
	DanaGF22529	Uncharacterized protein, isoform D. (1506 aa)
	DanaGF22262	Uncharacterized protein. (718 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10376	DanaGF10539	B3M9W5	B3M4J8	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.941
DanaGF10376	DanaGF20060	B3M9W5	B3M4T0	Uncharacterized protein.	Uncharacterized protein.	0.594
DanaGF10539	DanaGF10376	B3M4J8	B3M9W5	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.941
DanaGF10539	DanaGF11657	B3M4J8	B3MIF7	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.920
DanaGF10539	DanaGF12221	B3M4J8	B3MI97	Uncharacterized protein, isoform D.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
DanaGF10539	DanaGF13635	B3M4J8	A0A0N8P0G2	Uncharacterized protein, isoform D.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
DanaGF10539	DanaGF14597	B3M4J8	B3MJD3	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.941
DanaGF10539	DanaGF15519	B3M4J8	B3MLM4	Uncharacterized protein, isoform D.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
DanaGF10539	DanaGF17083	B3M4J8	B3M2A4	Uncharacterized protein, isoform D.	Mothers against decapentaplegic homolog.	0.864
DanaGF10539	DanaGF17542	B3M4J8	B3LW28	Uncharacterized protein, isoform D.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.432
DanaGF10539	DanaGF20060	B3M4J8	B3M4T0	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.799
DanaGF10539	DanaGF20577	B3M4J8	A0A0P8XDS3	Uncharacterized protein, isoform D.	Mothers against decapentaplegic homolog.	0.599
DanaGF10539	DanaGF20585	B3M4J8	A0A0P8XDR4	Uncharacterized protein, isoform D.	Uncharacterized protein, isoform B.	0.434
DanaGF10539	DanaGF20979	B3M4J8	B3MRL0	Uncharacterized protein, isoform D.	Mothers against decapentaplegic homolog.	0.856
DanaGF10539	DanaGF22262	B3M4J8	B3MZ49	Uncharacterized protein, isoform D.	Uncharacterized protein.	0.729
DanaGF10539	DanaGF22974	B3M4J8	B3MSY9	Uncharacterized protein, isoform D.	Mothers against decapentaplegic homolog.	0.756
DanaGF10539	DanaGF24409	B3M4J8	B3M5G3	Uncharacterized protein, isoform D.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.436
DanaGF11657	DanaGF10539	B3MIF7	B3M4J8	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.920
DanaGF11657	DanaGF12221	B3MIF7	B3MI97	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.993
DanaGF11657	DanaGF12511	B3MIF7	B3ME90	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.414