(6 nodes) Peptidyl-diphthamide metabolic process network (Drosophila ananassae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	DanaGF18658	Uncharacterized protein, isoform A. (186 aa)
	DanaGF18124	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (472 aa)
	DanaGF16743	DPH-type MB domain-containing protein. (86 aa)
	DanaGF16145	TP_methylase domain-containing protein. (281 aa)
	DanaGF16144	Uncharacterized protein. (298 aa)
	DanaGF24524	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (456 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF16144	DanaGF16743	B3M005	B3LZ50	Uncharacterized protein.	DPH-type MB domain-containing protein.	0.798
DanaGF16144	DanaGF18124	B3M005	B3LWQ5	Uncharacterized protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	0.961
DanaGF16144	DanaGF18658	B3M005	B3LWG4	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.886
DanaGF16144	DanaGF24524	B3M005	B3M4A9	Uncharacterized protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.932
DanaGF16145	DanaGF16743	B3M004	B3LZ50	TP_methylase domain-containing protein.	DPH-type MB domain-containing protein.	0.729
DanaGF16145	DanaGF18124	B3M004	B3LWQ5	TP_methylase domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	0.961
DanaGF16145	DanaGF18658	B3M004	B3LWG4	TP_methylase domain-containing protein.	Uncharacterized protein, isoform A.	0.884
DanaGF16145	DanaGF24524	B3M004	B3M4A9	TP_methylase domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.935
DanaGF16743	DanaGF16144	B3LZ50	B3M005	DPH-type MB domain-containing protein.	Uncharacterized protein.	0.798
DanaGF16743	DanaGF16145	B3LZ50	B3M004	DPH-type MB domain-containing protein.	TP_methylase domain-containing protein.	0.729
DanaGF16743	DanaGF18124	B3LZ50	B3LWQ5	DPH-type MB domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	0.996
DanaGF16743	DanaGF18658	B3LZ50	B3LWG4	DPH-type MB domain-containing protein.	Uncharacterized protein, isoform A.	0.887
DanaGF16743	DanaGF24524	B3LZ50	B3M4A9	DPH-type MB domain-containing protein.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.996
DanaGF18124	DanaGF16144	B3LWQ5	B3M005	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	Uncharacterized protein.	0.961
DanaGF18124	DanaGF16145	B3LWQ5	B3M004	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	TP_methylase domain-containing protein.	0.961
DanaGF18124	DanaGF16743	B3LWQ5	B3LZ50	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	DPH-type MB domain-containing protein.	0.996
DanaGF18124	DanaGF18658	B3LWQ5	B3LWG4	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	Uncharacterized protein, isoform A.	0.890
DanaGF18124	DanaGF24524	B3LWQ5	B3M4A9	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.	2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.	0.996
DanaGF18658	DanaGF16144	B3LWG4	B3M005	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.886
DanaGF18658	DanaGF16145	B3LWG4	B3M004	Uncharacterized protein, isoform A.	TP_methylase domain-containing protein.	0.884