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KATNA1 KATNA1 GF17837 GF17837 DanaGF18411 DanaGF18411 DanaGF17044 DanaGF17044 spas spas spn-E spn-E DanaGF18565 DanaGF18565 DanaGF25191 DanaGF25191 DanaGF10451 DanaGF10451 DanaGF24509 DanaGF24509 DanaGF10050 DanaGF10050 DanaGF10567 DanaGF10567 DanaGF23857 DanaGF23857 DanaGF10581 DanaGF10581 DanaGF20124 DanaGF20124 DanaGF23742 DanaGF23742 DanaGF23724 DanaGF23724 DanaGF24298 DanaGF24298 DanaGF24048 DanaGF24048 DanaGF10956 DanaGF10956 DanaGF11025 DanaGF11025 DanaGF12936 DanaGF12936 DanaGF13525 DanaGF13525 DanaGF11326 DanaGF11326 DanaGF21023 DanaGF21023 DanaGF27767 DanaGF27767 DanaGF26355 DanaGF26355 DanaGF11924 DanaGF11924 DanaGF24939 DanaGF24939 DanaGF16007 DanaGF16007 DanaGF16329 DanaGF16329 DanaGF17549 DanaGF17549 Lhr Lhr DanaGF17453 DanaGF17453 Spc25 Spc25 DanaGF18662 DanaGF18662 DanaGF16326 DanaGF16326 DanaGF16313 DanaGF16313 DanaGF17656 DanaGF17656 DanaGF17669 DanaGF17669 DanaGF16229 DanaGF16229 DanaGF16075 DanaGF16075 DanaGF22219 DanaGF22219 DanaGF22059 DanaGF22059 DanaGF19550 DanaGF19550 DanaGF11681 DanaGF11681 DanaGF20565 DanaGF20565 DanaGF22373 DanaGF22373 DanaGF22385 DanaGF22385 DanaGF22038 DanaGF22038 DanaGF22049 DanaGF22049 DanaGF24482 DanaGF24482 DanaGF24329 DanaGF24329 DanaGF22970 DanaGF22970 DanaGF21472 DanaGF21472 DanaGF20926 DanaGF20926 brk brk DanaGF20258 DanaGF20258 DanaGF20260 DanaGF20260 DanaGF20394 DanaGF20394 DanaGF20365 DanaGF20365 DanaGF15772 DanaGF15772 DanaGF15688 DanaGF15688 DanaGF15204 DanaGF15204 DanaGF15632 DanaGF15632 DanaGF14261 DanaGF14261 DanaGF15146 DanaGF15146 DanaGF15126 DanaGF15126 DanaGF14880 DanaGF14880 DanaGF14993 DanaGF14993 DanaGF15460 DanaGF15460 DanaGF14447 DanaGF14447 DanaGF15436 DanaGF15436 DanaGF14046 DanaGF14046 DanaGF14057 DanaGF14057 DanaGF12443 DanaGF12443 DanaGF12549 DanaGF12549 DanaGF12385 DanaGF12385 DanaGF13088 DanaGF13088 DanaGF13100 DanaGF13100 DanaGF11775 DanaGF11775 DanaGF12757 DanaGF12757 DanaGF12704 DanaGF12704 DanaGF13735 DanaGF13735 DanaGF13218 DanaGF13218 DanaGF12257 DanaGF12257 DanaGF12284 DanaGF12284 DanaGF11159 DanaGF11159
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (572 aa)
GF17837MAU2 chromatid cohesion factor homolog; Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity). (639 aa)
DanaGF18411SLBP_RNA_bind domain-containing protein. (272 aa)
DanaGF17044Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (334 aa)
spasSpastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (770 aa)
spn-EProbable ATP-dependent RNA helicase spindle-E; Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons. Involved in the repression of LTR retrotransposon copia. Also involved in telomere regulation by repres [...] (1429 aa)
DanaGF18565Protein kinase domain-containing protein. (603 aa)
DanaGF25191Uncharacterized protein. (1091 aa)
DanaGF10451Peptidase C50 domain-containing protein. (635 aa)
DanaGF24509Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (487 aa)
DanaGF10050Uncharacterized protein. (575 aa)
DanaGF10567Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (887 aa)
DanaGF23857N-acetyltransferase domain-containing protein. (941 aa)
DanaGF10581NUDE_C domain-containing protein. (325 aa)
DanaGF20124Uncharacterized protein. (149 aa)
DanaGF23742Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (805 aa)
DanaGF23724VWFA domain-containing protein. (392 aa)
DanaGF24298Uncharacterized protein. (1506 aa)
DanaGF24048Uncharacterized protein, isoform A. (1268 aa)
DanaGF10956GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (307 aa)
DanaGF11025BCNT-C domain-containing protein. (236 aa)
DanaGF12936Cnd3 domain-containing protein. (1417 aa)
DanaGF13525Uncharacterized protein, isoform A. (3229 aa)
DanaGF11326Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (514 aa)
DanaGF21023Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1378 aa)
DanaGF27767Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (684 aa)
DanaGF26355Nipped-B protein. (2054 aa)
DanaGF11924Uncharacterized protein, isoform D. (2100 aa)
DanaGF24939Uncharacterized protein, isoform F. (16983 aa)
DanaGF16007Uncharacterized protein, isoform B. (1347 aa)
DanaGF16329Uncharacterized protein, isoform B; Belongs to the DEAD box helicase family. (787 aa)
DanaGF17549Uncharacterized protein, isoform B. (1001 aa)
LhrLethal hybrid rescue protein. (321 aa)
DanaGF17453Leishmanolysin-like peptidase. (696 aa)
Spc25Kinetochore protein Spc25; Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing [...] (215 aa)
DanaGF18662Uncharacterized protein. (1260 aa)
DanaGF16326Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (702 aa)
DanaGF16313Uncharacterized protein, isoform A. (738 aa)
DanaGF17656GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (284 aa)
DanaGF17669Uncharacterized protein. (388 aa)
DanaGF16229Uncharacterized protein. (620 aa)
DanaGF16075Uncharacterized protein. (586 aa)
DanaGF22219Uncharacterized protein. (721 aa)
DanaGF22059Uncharacterized protein. (854 aa)
DanaGF19550Uncharacterized protein. (1515 aa)
DanaGF11681Uncharacterized protein. (719 aa)
DanaGF20565Uncharacterized protein. (711 aa)
DanaGF22373Uncharacterized protein. (669 aa)
DanaGF22385Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1383 aa)
DanaGF22038Uncharacterized protein. (318 aa)
DanaGF22049Uncharacterized protein. (218 aa)
DanaGF24482Uncharacterized protein. (407 aa)
DanaGF24329Structural maintenance of chromosomes protein. (1404 aa)
DanaGF22970Rod_C domain-containing protein. (2093 aa)
DanaGF21472Structural maintenance of chromosomes protein. (1200 aa)
DanaGF20926Uncharacterized protein. (576 aa)
brkBrinker. (672 aa)
DanaGF20258Uncharacterized protein. (611 aa)
DanaGF20260Uncharacterized protein. (702 aa)
DanaGF20394Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (826 aa)
DanaGF20365Uncharacterized protein. (188 aa)
DanaGF15772Uncharacterized protein. (205 aa)
DanaGF15688AAA domain-containing protein; Belongs to the AAA ATPase family. (553 aa)
DanaGF15204Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (458 aa)
DanaGF15632DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1456 aa)
DanaGF14261AAA_16 domain-containing protein. (460 aa)
DanaGF15146Uncharacterized protein. (1276 aa)
DanaGF15126Uncharacterized protein, isoform B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2182 aa)
DanaGF14880Uncharacterized protein. (198 aa)
DanaGF14993Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (473 aa)
DanaGF15460Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (742 aa)
DanaGF14447Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1120 aa)
DanaGF15436SCD domain-containing protein. (1127 aa)
DanaGF14046Uncharacterized protein; Belongs to the argonaute family. (873 aa)
DanaGF14057Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (329 aa)
DanaGF12443Uncharacterized protein, isoform B. (559 aa)
DanaGF12549N-acetyltransferase domain-containing protein. (184 aa)
DanaGF12385Uncharacterized protein. (380 aa)
DanaGF13088Uncharacterized protein. (730 aa)
DanaGF13100TPR_MLP1_2 domain-containing protein. (2338 aa)
DanaGF11775Structural maintenance of chromosomes protein. (1179 aa)
DanaGF12757Uncharacterized protein. (208 aa)
DanaGF12704INCENP_ARK-bind domain-containing protein. (750 aa)
DanaGF13735Myb_DNA-bind_5 domain-containing protein. (232 aa)
DanaGF13218Uncharacterized protein. (1385 aa)
DanaGF12257Uncharacterized protein. (425 aa)
DanaGF12284Uncharacterized protein, isoform A. (1217 aa)
DanaGF11159Uncharacterized protein. (624 aa)
Your Current Organism:
Drosophila ananassae
NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae
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