91 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF22940	Uncharacterized protein, isoform A. (1266 aa)
	DanaGF22645	Uncharacterized protein, isoform A. (888 aa)
	DanaGF13958	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (295 aa)
	DanaGF22818	Uncharacterized protein. (900 aa)
	DanaGF22234	Uncharacterized protein. (396 aa)
	DanaGF21769	Uncharacterized protein. (612 aa)
	DanaGF19146	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1234 aa)
	DanaGF16011	ANK_REP_REGION domain-containing protein. (146 aa)
	DanaGF20767	Uncharacterized protein. (182 aa)
	DanaGF16809	RRM domain-containing protein. (1060 aa)
	DanaGF17609	Uncharacterized protein, isoform A. (535 aa)
	DanaGF18592	Uncharacterized protein, isoform C. (707 aa)
	DanaGF16437	Fork-head domain-containing protein. (652 aa)
	DanaGF23407	Uncharacterized protein, isoform B. (454 aa)
	DanaGF13879	Uncharacterized protein, isoform C; Belongs to the protein kinase superfamily. (351 aa)
	DanaGF16779	Uncharacterized protein, isoform B. (724 aa)
	DanaGF10396	Uncharacterized protein, isoform B. (1105 aa)
	DanaGF15668	Uncharacterized protein, isoform C. (1367 aa)
	DanaGF22867	Uncharacterized protein, isoform B. (781 aa)
	DanaGF17645	Uncharacterized protein, isoform B. (2207 aa)
	DanaGF10866	Uncharacterized protein, isoform B. (875 aa)
	DanaGF27626	Cyclin_C domain-containing protein. (175 aa)
	DanaGF26758	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (657 aa)
	DanaGF27276	Uncharacterized protein. (1054 aa)
	DanaGF26483	Raptor_N domain-containing protein. (1459 aa)
	DanaGF18823	Uncharacterized protein, isoform B. (1601 aa)
	DanaGF17811	Uncharacterized protein, isoform B. (2121 aa)
	DanaGF11157	Uncharacterized protein, isoform AU. (8872 aa)
	DanaGF14429	Uncharacterized protein, isoform C. (2050 aa)
	DanaGF19606	BHLH domain-containing protein. (711 aa)
	foxo	Forkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...] (600 aa)
	DanaGF17274	Uncharacterized protein. (311 aa)
	DanaGF17707	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (438 aa)
	DanaGF16155	Uncharacterized protein. (602 aa)
	DanaGF17759	USP domain-containing protein; Belongs to the peptidase C19 family. (3907 aa)
	DanaGF17217	Uncharacterized protein, isoform B. (542 aa)
	DanaGF18327	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family. (1099 aa)
	DanaGF16119	MFS domain-containing protein. (568 aa)
	DanaGF16105	Uncharacterized protein. (1107 aa)
	DanaGF18932	Uncharacterized protein. (493 aa)
	DanaGF17134	Agenet-like domain-containing protein. (711 aa)
	spas	Spastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (770 aa)
	DanaGF16456	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1098 aa)
	DanaGF24601	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (623 aa)
	DanaGF10442	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (489 aa)
	DanaGF10447	Uncharacterized protein. (274 aa)
	DanaGF10474	Protein kinase domain-containing protein. (224 aa)
	DanaGF25310	Rap-GAP domain-containing protein. (1828 aa)
	DanaGF10067	Uncharacterized protein. (192 aa)
	DanaGF10124	HTH La-type RNA-binding domain-containing protein. (1532 aa)
	DanaGF10137	Uncharacterized protein. (611 aa)
	DanaGF24365	Uncharacterized protein. (181 aa)
	DanaGF10169	BHLH domain-containing protein. (398 aa)
	DanaGF24880	Uncharacterized protein, isoform A. (841 aa)
	DanaGF10204	Uncharacterized protein. (532 aa)
	DanaGF24217	Uncharacterized protein. (770 aa)
	DanaGF25032	Uncharacterized protein. (643 aa)
	DanaGF24119	Uncharacterized protein, isoform A. (261 aa)
	DanaGF24678	IlGF domain-containing protein. (137 aa)
	DanaGF10969	Uncharacterized protein. (519 aa)
	DanaGF12130	Lactamase_B domain-containing protein. (768 aa)
	DanaGF11995	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (332 aa)
	DanaGF11965	Robl_LC7 domain-containing protein. (125 aa)
	DanaGF11396	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (326 aa)
	DanaGF13031	Uncharacterized protein. (580 aa)
	DanaGF13078	Uncharacterized protein, isoform A. (501 aa)
	DanaGF13596	Uncharacterized protein, isoform A; Belongs to the semaphorin family. (742 aa)
	DanaGF13604	Uncharacterized protein, isoform A; Belongs to the semaphorin family. (721 aa)
	DanaGF12702	Uncharacterized protein. (986 aa)
	DanaGF12229	Vang-like protein. (609 aa)
	DanaGF13235	Uncharacterized protein, isoform A; Belongs to the semaphorin family. (753 aa)
	DanaGF13772	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (3643 aa)
	DanaGF11046	Uncharacterized protein. (269 aa)
	DanaGF14540	Uncharacterized protein, isoform A; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	DanaGF14539	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
	DanaGF14538	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	DanaGF14949	Uncharacterized protein. (1216 aa)
	DanaGF15536	Sema domain-containing protein; Belongs to the semaphorin family. (1143 aa)
	DanaGF15089	Uncharacterized protein, isoform A; Cadherins are calcium-dependent cell adhesion proteins. (3097 aa)
	DanaGF14290	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	DanaGF14216	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2470 aa)
	DanaGF14206	Uncharacterized protein. (390 aa)
	DanaGF15239	Uncharacterized protein. (117 aa)
	DanaGF14124	Uncharacterized protein, isoform A. (512 aa)
	DanaGF20269	FERM domain-containing protein. (635 aa)
	DanaGF21190	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	DanaGF21013	Non-specific serine/threonine protein kinase. (581 aa)
	DanaGF20855	Uncharacterized protein. (340 aa)
	DanaGF20822	Uncharacterized protein, isoform A. (1303 aa)
	DanaGF23293	Uncharacterized protein, isoform B; Belongs to the protein kinase superfamily. (441 aa)
	DanaGF20886	Uncharacterized protein, isoform A. (181 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10067	DanaGF12229	B3M528	B3MI75	Uncharacterized protein.	Vang-like protein.	0.511
DanaGF10067	DanaGF12702	B3M528	B3MI57	Uncharacterized protein.	Uncharacterized protein.	0.415
DanaGF10067	DanaGF14290	B3M528	B3MMQ1	Uncharacterized protein.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.686
DanaGF10067	DanaGF15536	B3M528	B3MLY1	Uncharacterized protein.	Sema domain-containing protein; Belongs to the semaphorin family.	0.412
DanaGF10067	DanaGF16105	B3M528	B3M0M0	Uncharacterized protein.	Uncharacterized protein.	0.464
DanaGF10067	DanaGF16155	B3M528	B3LZY7	Uncharacterized protein.	Uncharacterized protein.	0.562
DanaGF10067	DanaGF17134	B3M528	B3M1T0	Uncharacterized protein.	Agenet-like domain-containing protein.	0.780
DanaGF10067	DanaGF18327	B3M528	B3M0A8	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family.	0.503
DanaGF10067	DanaGF19146	B3M528	B3N0S7	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.538
DanaGF10067	DanaGF20269	B3M528	B3MQC8	Uncharacterized protein.	FERM domain-containing protein.	0.438
DanaGF10067	DanaGF21769	B3M528	B3N091	Uncharacterized protein.	Uncharacterized protein.	0.660
DanaGF10067	DanaGF24880	B3M528	B3M6L6	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.475
DanaGF10067	DanaGF26483	B3M528	A0A0P8Y4C2	Uncharacterized protein.	Raptor_N domain-containing protein.	0.435
DanaGF10442	DanaGF11965	B3M3L7	B3MDG7	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Robl_LC7 domain-containing protein.	0.579
DanaGF10442	DanaGF13078	B3M3L7	B3MFJ6	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein, isoform A.	0.624
DanaGF10442	DanaGF14124	B3M3L7	B3MPP1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein, isoform A.	0.891
DanaGF10442	DanaGF14216	B3M3L7	B3MNH4	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.998
DanaGF10442	DanaGF15239	B3M3L7	B3MP27	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein.	0.902
DanaGF10442	DanaGF15668	B3M3L7	A0A0P8ZG90	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein, isoform C.	0.502
DanaGF10442	DanaGF16105	B3M3L7	B3M0M0	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein.	0.918