(72 nodes) SCF ubiquitin ligase complex network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF15683	Uncharacterized protein, isoform B. (486 aa)
	DanaGF15988	F-box domain-containing protein. (675 aa)
	DanaGF21540	Uncharacterized protein, isoform A. (315 aa)
	DanaGF23401	Uncharacterized protein. (445 aa)
	DanaGF22718	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (75 aa)
	DanaGF24066	Uncharacterized protein. (478 aa)
	DanaGF22879	WD_REPEATS_REGION domain-containing protein. (460 aa)
	DanaGF21496	RING-type domain-containing protein. (146 aa)
	DanaGF20771	RING-type domain-containing protein. (154 aa)
	DanaGF20772	RING-type domain-containing protein. (133 aa)
	DanaGF20947	Uncharacterized protein. (419 aa)
	DanaGF20982	Uncharacterized protein, isoform A. (1280 aa)
	DanaGF21274	Uncharacterized protein. (305 aa)
	DanaGF21176	Uncharacterized protein, isoform B; Belongs to the SKP1 family. (163 aa)
	DanaGF20493	RING-type domain-containing protein. (194 aa)
	DanaGF15713	Uncharacterized protein. (357 aa)
	DanaGF15696	Uncharacterized protein. (317 aa)
	DanaGF19685	Uncharacterized protein. (244 aa)
	DanaGF15531	Uncharacterized protein. (405 aa)
	DanaGF15487	CULLIN_2 domain-containing protein; Belongs to the cullin family. (748 aa)
	DanaGF15444	Uncharacterized protein. (410 aa)
	DanaGF15431	IBR domain-containing protein. (348 aa)
	DanaGF14490	N-acetyltransferase domain-containing protein. (293 aa)
	DanaGF15406	Uncharacterized protein. (661 aa)
	DanaGF13252	F-box domain-containing protein. (568 aa)
	DanaGF11651	F-box domain-containing protein. (664 aa)
	DanaGF13243	RRM domain-containing protein. (632 aa)
	DanaGF11136	Uncharacterized protein, isoform A; Belongs to the SKP1 family. (161 aa)
	DanaGF13725	Uncharacterized protein, isoform A. (605 aa)
	DanaGF12644	Uncharacterized protein, isoform A; Belongs to the SKP1 family. (161 aa)
	DanaGF13681	Uncharacterized protein. (314 aa)
	DanaGF11745	F-box domain-containing protein. (516 aa)
	DanaGF13641	CULLIN_2 domain-containing protein; Belongs to the cullin family. (775 aa)
	DanaGF11789	Uncharacterized protein, isoform A. (637 aa)
	DanaGF11848	Uncharacterized protein; Belongs to the SKP1 family. (197 aa)
	DanaGF12565	F-box domain-containing protein. (710 aa)
	DanaGF12419	Uncharacterized protein, isoform A. (783 aa)
	Fsn	F-box/SPRY domain-containing protein 1; Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ); Belongs to the FBXO45/Fsn family. (255 aa)
	DanaGF25176	CULLIN_2 domain-containing protein; Belongs to the cullin family. (582 aa)
	DanaGF23504	Uncharacterized protein. (456 aa)
	DanaGF24660	F-box domain-containing protein. (316 aa)
	DanaGF23509	F-box domain-containing protein. (452 aa)
	DanaGF24101	B30.2/SPRY domain-containing protein. (339 aa)
	DanaGF24115	Uncharacterized protein, isoform A. (284 aa)
	DanaGF24141	F-box domain-containing protein. (415 aa)
	DanaGF23596	F-box domain-containing protein. (432 aa)
	DanaGF23620	Uncharacterized protein. (400 aa)
	DanaGF24221	Uncharacterized protein; Belongs to the SKP1 family. (155 aa)
	DanaGF10232	F-box domain-containing protein. (323 aa)
	DanaGF24894	RING-type domain-containing protein. (119 aa)
	DanaGF10166	Uncharacterized protein. (343 aa)
	DanaGF23871	Uncharacterized protein. (1276 aa)
	DanaGF24522	Uncharacterized protein. (354 aa)
	DanaGF24527	Uncharacterized protein. (666 aa)
	DanaGF18550	F-box domain-containing protein. (771 aa)
	DanaGF18514	Uncharacterized protein. (614 aa)
	DanaGF17039	Uncharacterized protein, isoform A. (438 aa)
	DanaGF16580	Uncharacterized protein. (1333 aa)
	DanaGF17149	Uncharacterized protein. (1185 aa)
	DanaGF18791	F-box domain-containing protein. (632 aa)
	DanaGF16754	Uncharacterized protein. (307 aa)
	DanaGF16815	F-box domain-containing protein. (561 aa)
	DanaGF16842	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (98 aa)
	DanaGF17402	RING-type domain-containing protein. (141 aa)
	DanaGF18683	F-box domain-containing protein. (742 aa)
	DanaGF26594	RRM domain-containing protein. (600 aa)
	DanaGF22186	Uncharacterized protein, isoform B. (141 aa)
	DanaGF23347	Uncharacterized protein, isoform C. (515 aa)
	DanaGF26426	Uncharacterized protein; Belongs to the SKP1 family. (156 aa)
	DanaGF26605	F-box domain-containing protein. (414 aa)
	DanaGF27637	Uncharacterized protein, isoform B. (250 aa)
	DanaGF20031	Uncharacterized protein, isoform D. (418 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF11136	DanaGF11789	B3MHI5	B3MG54	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein, isoform A.	0.689
DanaGF11136	DanaGF12419	B3MHI5	B3MEU0	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein, isoform A.	0.560
DanaGF11136	DanaGF12644	B3MHI5	B3MH30	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	0.900
DanaGF11136	DanaGF13252	B3MHI5	B3MIW7	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	F-box domain-containing protein.	0.584
DanaGF11136	DanaGF13641	B3MHI5	B3MGA3	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.994
DanaGF11136	DanaGF14490	B3MHI5	B3MKK5	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	N-acetyltransferase domain-containing protein.	0.426
DanaGF11136	DanaGF15406	B3MHI5	B3MKI6	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein.	0.765
DanaGF11136	DanaGF15487	B3MHI5	B3ML83	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.496
DanaGF11136	DanaGF15713	B3MHI5	B3MP86	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein.	0.422
DanaGF11136	DanaGF15988	B3MHI5	B3N124	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	F-box domain-containing protein.	0.486
DanaGF11136	DanaGF16580	B3MHI5	B3M1Z5	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein.	0.977
DanaGF11136	DanaGF16815	B3MHI5	B3LY05	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	F-box domain-containing protein.	0.962
DanaGF11136	DanaGF16842	B3MHI5	B3LXG6	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.540
DanaGF11136	DanaGF17039	B3MHI5	B3M2S1	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein, isoform A.	0.807
DanaGF11136	DanaGF17149	B3MHI5	B3M1D3	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein.	0.730
DanaGF11136	DanaGF17402	B3MHI5	B3LX43	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	RING-type domain-containing protein.	0.906
DanaGF11136	DanaGF18514	B3MHI5	B3M2V7	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	Uncharacterized protein.	0.992
DanaGF11136	DanaGF18550	B3MHI5	B3M394	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	F-box domain-containing protein.	0.560
DanaGF11136	DanaGF18683	B3MHI5	B3LX13	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	F-box domain-containing protein.	0.559
DanaGF11136	DanaGF20493	B3MHI5	B3MPU0	Uncharacterized protein, isoform A; Belongs to the SKP1 family.	RING-type domain-containing protein.	0.550