82 items (Drosophila ananassae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF18131	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	DanaGF13635	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (575 aa)
	DanaGF18500	Uncharacterized protein, isoform C. (327 aa)
	DanaGF20585	Uncharacterized protein, isoform B. (629 aa)
	DanaGF20577	Mothers against decapentaplegic homolog. (581 aa)
	DanaGF14414	Uncharacterized protein, isoform D. (768 aa)
	DanaGF17811	Uncharacterized protein, isoform B. (2121 aa)
	DanaGF18066	Uncharacterized protein, isoform B. (433 aa)
	DanaGF18582	Uncharacterized protein, isoform B. (359 aa)
	nos	Nanos, isoform B; Belongs to the nanos family. (408 aa)
	DanaGF16329	Uncharacterized protein, isoform B; Belongs to the DEAD box helicase family. (787 aa)
	DanaGF16463	Uncharacterized protein, isoform C. (1076 aa)
	DanaGF27773	Rhomboid domain-containing protein; Belongs to the peptidase S54 family. (330 aa)
	DanaGF12013	Uncharacterized protein, isoform C. (605 aa)
	DanaGF17542	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	DanaGF18660	Uncharacterized protein, isoform A. (594 aa)
	DanaGF17434	Uncharacterized protein. (444 aa)
	DanaGF18736	Peptidase S59 domain-containing protein. (1960 aa)
	DanaGF18773	Uncharacterized protein; Belongs to the LIMR family. (529 aa)
	DanaGF16147	Uncharacterized protein, isoform B. (448 aa)
	DanaGF18860	MPN domain-containing protein. (344 aa)
	DanaGF18327	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family. (1099 aa)
	DanaGF18432	Uncharacterized protein, isoform A. (759 aa)
	DanaGF17083	Mothers against decapentaplegic homolog. (568 aa)
	Dl-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (829 aa)
	DanaGF18480	Uncharacterized protein. (882 aa)
	DanaGF16530	LEM domain-containing protein. (403 aa)
	DanaGF16497	Uncharacterized protein. (185 aa)
	DanaGF18542	Uncharacterized protein, isoform A. (1550 aa)
	DanaGF16458	Histone H2A; Belongs to the histone H2A family. (141 aa)
	DanaGF18565	Protein kinase domain-containing protein. (603 aa)
	DanaGF25200	Uncharacterized protein, isoform A. (960 aa)
	DanaGF10442	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (489 aa)
	Usp36	Ubiquitin carboxyl-terminal hydrolase 36; Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). Controls selective autophagy activation by ubiquitinated proteins; Belongs to the peptidase C19 family. (1091 aa)
	DanaGF24360	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (623 aa)
	DanaGF10199	Uncharacterized protein. (413 aa)
	DanaGF10201	PCI domain-containing protein. (445 aa)
	DanaGF10211	Uncharacterized protein, isoform A. (415 aa)
	DanaGF24954	Uncharacterized protein, isoform B. (184 aa)
	DanaGF10799	PCI domain-containing protein. (524 aa)
	DanaGF25016	UDENN FLCN/SMCR8-type domain-containing protein. (461 aa)
	mael1	Protein maelstrom 1; Involved both in the piRNA and miRNA metabolic processes. As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons. As a nuclear component, it is required for proper differentiation in [...] (424 aa)
	DanaGF12772	LEM domain-containing protein. (481 aa)
	DanaGF12812	Uncharacterized protein, isoform A. (3199 aa)
	DanaGF12821	Receptor protein-tyrosine kinase. (1439 aa)
	DanaGF12023	MamL-1 domain-containing protein. (1653 aa)
	DanaGF12987	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (1508 aa)
	DanaGF11372	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2302 aa)
	DanaGF11365	Uncharacterized protein. (182 aa)
	DanaGF12511	TGF_BETA_2 domain-containing protein. (454 aa)
	DanaGF12453	Uncharacterized protein, isoform A. (1213 aa)
	DanaGF12354	PCI domain-containing protein. (280 aa)
	DanaGF13652	PCI domain-containing protein. (403 aa)
	DanaGF11153	Uncharacterized protein, isoform A; Belongs to the argonaute family. (984 aa)
	DanaGF13780	WD_REPEATS_REGION domain-containing protein. (460 aa)
	DanaGF14581	WD_REPEATS_REGION domain-containing protein. (529 aa)
	DanaGF14047	Uncharacterized protein; Belongs to the argonaute family. (861 aa)
	DanaGF14515	Uncharacterized protein, isoform D. (1577 aa)
	DanaGF15519	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (562 aa)
	DanaGF15083	Uncharacterized protein. (716 aa)
	DanaGF14290	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	DanaGF15595	Uncharacterized protein, isoform B; Belongs to the DEAD box helicase family. (403 aa)
	DanaGF14289	Uncharacterized protein. (1840 aa)
	DanaGF14192	Uncharacterized protein, isoform C. (840 aa)
	DanaGF14648	Ubiquitin-like domain-containing protein. (81 aa)
	DanaGF20357	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (367 aa)
	DanaGF20259	Histone H2A; Belongs to the histone H2A family. (182 aa)
	DanaGF21297	Integrin beta; Belongs to the integrin beta chain family. (864 aa)
	GF20802	Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (994 aa)
	DanaGF23202	Signal transducer and activator of transcription. (747 aa)
	DanaGF22974	Mothers against decapentaplegic homolog. (770 aa)
	DanaGF22944	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1442 aa)
	DanaGF20662	J domain-containing protein. (355 aa)
	DanaGF22104	PCI domain-containing protein. (444 aa)
	DanaGF22793	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (394 aa)
	DanaGF23153	Uncharacterized protein, isoform A. (472 aa)
	DanaGF22307	Uncharacterized protein. (736 aa)
	DanaGF22451	Tudor domain-containing protein. (1567 aa)
	Om(1E)	Optic morphology(1E). (461 aa)
	mael2	Protein maelstrom 2; Involved both in the piRNA and miRNA metabolic processes. As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons. As a nuclear component, it is required for proper differentiation in [...] (468 aa)
	DanaGF22755	Uncharacterized protein, isoform A. (608 aa)
	DanaGF19599	Uncharacterized protein. (2712 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10199	DanaGF19599	B3M6V8	B3N1W3	Uncharacterized protein.	Uncharacterized protein.	0.989
DanaGF10199	DanaGF22944	B3M6V8	B3MT39	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.900
DanaGF10199	Dl-2	B3M6V8	B3M2E0	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.459
DanaGF10201	DanaGF10799	B3M6W2	B3M853	PCI domain-containing protein.	PCI domain-containing protein.	0.996
DanaGF10201	DanaGF12354	B3M6W2	B3MFZ1	PCI domain-containing protein.	PCI domain-containing protein.	0.997
DanaGF10201	DanaGF13652	B3M6W2	B3MGC3	PCI domain-containing protein.	PCI domain-containing protein.	0.999
DanaGF10201	DanaGF14648	B3M6W2	B3MPE2	PCI domain-containing protein.	Ubiquitin-like domain-containing protein.	0.959
DanaGF10201	DanaGF18500	B3M6W2	A0A0N8P1L7	PCI domain-containing protein.	Uncharacterized protein, isoform C.	0.999
DanaGF10201	DanaGF18860	B3M6W2	B3M003	PCI domain-containing protein.	MPN domain-containing protein.	0.998
DanaGF10201	DanaGF22104	B3M6W2	B3MUR3	PCI domain-containing protein.	PCI domain-containing protein.	0.999
DanaGF10442	DanaGF15595	B3M3L7	B3MMQ2	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein, isoform B; Belongs to the DEAD box helicase family.	0.608
DanaGF10442	DanaGF17542	B3M3L7	B3LW28	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.427
DanaGF10442	DanaGF17811	B3M3L7	A0A0P8XY38	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein, isoform B.	0.835
DanaGF10442	DanaGF18327	B3M3L7	B3M0A8	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Uncharacterized protein, isoform A; Belongs to the PI3/PI4-kinase family.	0.609
DanaGF10799	DanaGF10201	B3M853	B3M6W2	PCI domain-containing protein.	PCI domain-containing protein.	0.996
DanaGF10799	DanaGF12354	B3M853	B3MFZ1	PCI domain-containing protein.	PCI domain-containing protein.	0.995
DanaGF10799	DanaGF13652	B3M853	B3MGC3	PCI domain-containing protein.	PCI domain-containing protein.	0.996
DanaGF10799	DanaGF14648	B3M853	B3MPE2	PCI domain-containing protein.	Ubiquitin-like domain-containing protein.	0.915
DanaGF10799	DanaGF18500	B3M853	A0A0N8P1L7	PCI domain-containing protein.	Uncharacterized protein, isoform C.	0.997
DanaGF10799	DanaGF18860	B3M853	B3M003	PCI domain-containing protein.	MPN domain-containing protein.	0.997