(13 nodes) Tumor necrosis factor-mediated signaling pathway network (Drosophila ananassae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF12016	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family. (430 aa)
	DanaGF15984	Protein kinase domain-containing protein. (732 aa)
	DanaGF19567	Uncharacterized protein, isoform A. (473 aa)
	DanaGF22405	TNFR-Cys domain-containing protein. (384 aa)
	DanaGF21403	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	DanaGF20874	Protein kinase domain-containing protein. (1170 aa)
	DanaGF20974	Uncharacterized protein. (476 aa)
	DanaGF14126	Mitogen-activated protein kinase. (376 aa)
	DanaGF13242	Uncharacterized protein, isoform A. (840 aa)
	DanaGF25017	Uncharacterized protein, isoform C. (1532 aa)
	DanaGF18815	Uncharacterized protein, isoform A. (732 aa)
	DanaGF16332	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	DanaGF15056	Uncharacterized protein, isoform B. (240 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF12016	DanaGF14126	A0A0P8XNE7	B3MPN7	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family.	Mitogen-activated protein kinase.	0.753
DanaGF12016	DanaGF15056	A0A0P8XNE7	A0A0P8Y325	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family.	Uncharacterized protein, isoform B.	0.868
DanaGF12016	DanaGF15984	A0A0P8XNE7	B3N113	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein.	0.756
DanaGF12016	DanaGF22405	A0A0P8XNE7	B3MWQ7	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family.	TNFR-Cys domain-containing protein.	0.625
DanaGF13242	DanaGF15984	B3MIG0	B3N113	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.999
DanaGF13242	DanaGF16332	B3MIG0	B3LWW8	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.549
DanaGF13242	DanaGF19567	B3MIG0	B3N0R7	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.898
DanaGF13242	DanaGF20874	B3MIG0	B3MS41	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein.	0.613
DanaGF13242	DanaGF20974	B3MIG0	B3MRL9	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.995
DanaGF13242	DanaGF21403	B3MIG0	B3MS42	Uncharacterized protein, isoform A.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.661
DanaGF13242	DanaGF22405	B3MIG0	B3MWQ7	Uncharacterized protein, isoform A.	TNFR-Cys domain-containing protein.	0.594
DanaGF14126	DanaGF12016	B3MPN7	A0A0P8XNE7	Mitogen-activated protein kinase.	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family.	0.753
DanaGF14126	DanaGF15056	B3MPN7	A0A0P8Y325	Mitogen-activated protein kinase.	Uncharacterized protein, isoform B.	0.593
DanaGF14126	DanaGF15984	B3MPN7	B3N113	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.604
DanaGF14126	DanaGF16332	B3MPN7	B3LWW8	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
DanaGF14126	DanaGF20874	B3MPN7	B3MS41	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.999
DanaGF14126	DanaGF21403	B3MPN7	B3MS42	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.738
DanaGF14126	DanaGF22405	B3MPN7	B3MWQ7	Mitogen-activated protein kinase.	TNFR-Cys domain-containing protein.	0.595
DanaGF15056	DanaGF12016	A0A0P8Y325	A0A0P8XNE7	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform B; Belongs to the tumor necrosis factor family.	0.868
DanaGF15056	DanaGF14126	A0A0P8Y325	B3MPN7	Uncharacterized protein, isoform B.	Mitogen-activated protein kinase.	0.593