(45 nodes) Negative regulation of hippo signaling network (Drosophila ananassae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DanaGF27806	FHA domain-containing protein. (887 aa)
	DanaGF14574	Uncharacterized protein, isoform B. (757 aa)
	DanaGF12120	Non-specific serine/threonine protein kinase. (1478 aa)
	DanaGF24453	Uncharacterized protein, isoform B. (1063 aa)
	DanaGF27993	Uncharacterized protein. (204 aa)
	DanaGF12632	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (968 aa)
	DanaGF13334	Uncharacterized protein, isoform G. (3975 aa)
	DanaGF19089	Uncharacterized protein, isoform B. (710 aa)
	DanaGF11779	Uncharacterized protein, isoform AB. (1790 aa)
	DanaGF18032	Uncharacterized protein. (814 aa)
	DanaGF16155	Uncharacterized protein. (602 aa)
	DanaGF17866	Uncharacterized protein, isoform A. (1573 aa)
	DanaGF18514	Uncharacterized protein. (614 aa)
	DanaGF23912	Uncharacterized protein, isoform A. (930 aa)
	DanaGF10553	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
	DanaGF24954	Uncharacterized protein, isoform B. (184 aa)
	DanaGF24757	Uncharacterized protein, isoform A. (1332 aa)
	DanaGF24009	Non-specific serine/threonine protein kinase. (1845 aa)
	DanaGF13333	Uncharacterized protein. (4635 aa)
	DanaGF12906	Uncharacterized protein. (1882 aa)
	DanaGF13641	CULLIN_2 domain-containing protein; Belongs to the cullin family. (775 aa)
	DanaGF11717	Non-specific serine/threonine protein kinase. (1185 aa)
	DanaGF11696	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (913 aa)
	DanaGF11665	Uncharacterized protein. (353 aa)
	DanaGF11657	Uncharacterized protein. (1047 aa)
	DanaGF11645	Uncharacterized protein. (843 aa)
	DanaGF13799	Uncharacterized protein. (223 aa)
	DanaGF14597	Uncharacterized protein. (963 aa)
	DanaGF15342	Uncharacterized protein, isoform A. (1910 aa)
	DanaGF14468	Uncharacterized protein. (322 aa)
	DanaGF14875	Uncharacterized protein. (3563 aa)
	DanaGF15530	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1252 aa)
	DanaGF15221	Uncharacterized protein, isoform A. (666 aa)
	DanaGF21176	Uncharacterized protein, isoform B; Belongs to the SKP1 family. (163 aa)
	DanaGF21273	WD_REPEATS_REGION domain-containing protein. (343 aa)
	DanaGF21383	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
	DanaGF21403	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	DanaGF20860	Protein kinase domain-containing protein. (972 aa)
	DanaGF23258	N-acetyltransferase domain-containing protein. (199 aa)
	DanaGF21831	Serine/threonine-protein phosphatase. (309 aa)
	DanaGF23057	Mitogen-activated protein kinase. (365 aa)
	DanaGF19514	Uncharacterized protein; Belongs to the peptidase C19 family. (1144 aa)
	DanaGF21982	Protein kinase domain-containing protein. (1480 aa)
	DanaGF19046	Uncharacterized protein, isoform D. (1343 aa)
	DanaGF21884	Uncharacterized protein. (556 aa)

Your Current Organism:

Drosophila ananassae

NCBI taxonomy Id: 7217
Other names: D. ananassae, Drosophila annanassae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DanaGF10553	DanaGF11645	B3M4U9	B3MIH5	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.484
DanaGF11645	DanaGF10553	B3MIH5	B3M4U9	Uncharacterized protein.	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.484
DanaGF11645	DanaGF15342	B3MIH5	B3MJS4	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.448
DanaGF11645	DanaGF18514	B3MIH5	B3M2V7	Uncharacterized protein.	Uncharacterized protein.	0.574
DanaGF11645	DanaGF19514	B3MIH5	B3MXT1	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.440
DanaGF11657	DanaGF12632	B3MIF7	A0A0P8ZLZ9	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.850
DanaGF11657	DanaGF13641	B3MIF7	B3MGA3	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.448
DanaGF11657	DanaGF14597	B3MIF7	B3MJD3	Uncharacterized protein.	Uncharacterized protein.	0.901
DanaGF11657	DanaGF15342	B3MIF7	B3MJS4	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.496
DanaGF11657	DanaGF16155	B3MIF7	B3LZY7	Uncharacterized protein.	Uncharacterized protein.	0.506
DanaGF11657	DanaGF18514	B3MIF7	B3M2V7	Uncharacterized protein.	Uncharacterized protein.	0.666
DanaGF11657	DanaGF21176	B3MIF7	B3MQX8	Uncharacterized protein.	Uncharacterized protein, isoform B; Belongs to the SKP1 family.	0.418
DanaGF11665	DanaGF15530	B3MIE0	B3MLW9	Uncharacterized protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.807
DanaGF11665	DanaGF21273	B3MIE0	B3MRG1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.593
DanaGF11665	DanaGF24009	B3MIE0	B3MB20	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.488
DanaGF11717	DanaGF11779	B3MHB1	A0A0P9AET0	Non-specific serine/threonine protein kinase.	Uncharacterized protein, isoform AB.	0.593
DanaGF11717	DanaGF12632	B3MHB1	A0A0P8ZLZ9	Non-specific serine/threonine protein kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.641
DanaGF11717	DanaGF21831	B3MHB1	B3MV12	Non-specific serine/threonine protein kinase.	Serine/threonine-protein phosphatase.	0.424
DanaGF11779	DanaGF11717	A0A0P9AET0	B3MHB1	Uncharacterized protein, isoform AB.	Non-specific serine/threonine protein kinase.	0.593
DanaGF12120	DanaGF12632	A0A0P8XMW6	A0A0P8ZLZ9	Non-specific serine/threonine protein kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.422